Search results for "HYDRIDES"

showing 10 items of 42 documents

Hydrogels for potential colon drug release by thiol-ene conjugate addition of a new inulin derivative.

2008

Inulin was chosen as a starting polymer for biocompatible, pH-sensitive and biodegradable hydrogels. Three INUDVSA-TT hydrogels were obtained by crosslinking inulin derivatives with trimethylolpropane tris(3-mercaptopropionate) under varying conditions. The resulting hydrogels were cell compatible, as demonstrated by MTS and trypan blue exclusion assays acting on Caco-2 cells, and were biodegraded by inulinase and esterase, thus suggesting their use as colonic drug delivery systems. 2-Methoxyestradiol, an anti-cancer drug, was soaked in INUDVSA-TT hydrogels and its in vitro release and apoptotic effect on Caco-2 cells were evaluated.

Succinic AnhydridesPolymers and PlasticsCell SurvivalColonInulinBioengineeringmacromolecular substancesDNA Fragmentationcomplex mixturesBiomaterialschemistry.chemical_compoundDrug Delivery SystemsMaterials ChemistryOrganic chemistryHumansSulfhydryl CompoundsSulfonesHYDROGELS INULIN DRUG TARGETING COLON DELIVERYTrimethylolpropaneParticle SizeEstradioltechnology industry and agricultureInulinHydrogelsCombinatorial chemistry2-MethoxyestradiolMolecular WeightCross-Linking ReagentschemistrySettore CHIM/09 - Farmaceutico Tecnologico ApplicativoSelf-healing hydrogelsDrug deliveryBisbenzimidazoleLiberationTrypan blueCaco-2 CellsDrug carrierBiotechnologyConjugateMacromolecular bioscience
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Chromatographic and mass spectrometric characteristics of 20-dihydroaldosterone.

1992

The 20 alpha-reduced derivative of aldosterone, 20 alpha-dihydroaldosterone, was needed as reference compound in order to continue the studies on 18-hydroxylation in the Y-1 adrenal cell line. It was obtained by reduction of aldosterone with sodium borohydride. Analysis of the products of the reaction as methoxime trimethylsilyl (MO-TMS) derivatives by gas chromatography (GC) and GC-mass spectrometry (GC-MS) showed three possible forms of the compound. Their identification was confirmed by comparison with the products obtained by stereospecific reduction of aldosterone using 3 alpha,20 beta-hydroxysteroid dehydrogenase. Chromatographic behavior and mass spectra are given for the three forms…

Trimethylsilyl CompoundsChromatography GasTrimethylsilylClinical BiochemistryBorohydridesMass spectrometryBiochemistryHigh-performance liquid chromatographyGas Chromatography-Mass Spectrometrychemistry.chemical_compoundSodium borohydrideEndocrinologyMolecular BiologyAldosteroneChromatography High Pressure LiquidPharmacologyAldosteroneChromatographyMolecular StructureOrganic ChemistryReference StandardsDeuteriumchemistryMass spectrumGas chromatographyGas chromatography–mass spectrometryOxidation-ReductionEthersSteroids
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Macrocyclic peptides in anionic polymers of amino acid N-carboxylic anhydrides.

1976

chemistry.chemical_classificationChemistryChemical PhenomenaChemistryPolymersPolymer chemistryAnionic polymersGeneral MedicinePeptides CyclicAmino acidAnhydridesAngewandte Chemie (International ed. in English)
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Effect of nano-structuring on hydrogen sorption properties of LaNi5 systems

2010

hydrogen storage LaNi5 nanostructuring hydrides ball milling
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Hydrogen sorption properties of the CaH2-MgB2-AlB2 system

2011

hydrogen storage borohydrides RHC ball milling
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Hydrogen sorption in the CaH2+MgB2 system

2010

hydrogen storage borohydrides RHC ball milling
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Preparation and characterization of borohydrides-based reactive hydride composites (RHCs)

2011

hydrogen storage borohydrides RHCs
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Ball milling and AlB2 addition effects on the hydrogen sorption properties of the CaH2 + MgB2 system

2010

Among the borohydrides proposed for solid state hydrogen storage,Ca(BH4)2 is particularly interesting because of its favourable thermodynamics and relatively cheap price.Composite systems,whereother species are present in addition to the borohydride,show some advantages in hydrogen sorption properties with respect to the borohydrides alone,despite a reduction of the theoretical storage capacity. We have investigated the milling time influence on the sorption properties of the CaH2 +MgB2 system from which Ca(BH4)2 and MgH2 can be synthesized by hydrogen absorption process.Manometric and calorimetric measurements showed better kinetics forlong time milled samples.We found that the total subst…

hydrogen storage borohydrides ball milling hydrogen absorption sorption kinetics
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Hydrogen sorption properties of the composite system calcium hydride – magnesium boride

2010

hydrogen storage borohydrides nanostructuring ball milling RHC
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Dehydrogenation behaviour of mixed borohydrides dispersed on high specific surface area carbons

2011

hydrogen storage nanoconfinement nanoscaffolds borohydrides
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