Search results for "Hand"

showing 10 items of 1364 documents

Inside Cover: Synthesis and Application of β-Substituted Pauson-Khand Adducts: Trifluoromethyl as a Removable Steering Group (Angew. Chem. Int. Ed. 2…

2013

chemistry.chemical_compoundTrifluoromethylchemistryStereochemistryPauson–Khand reactionRegioselectivityCover (algebra)General ChemistrySteering groupCatalysisAdductAngewandte Chemie International Edition
researchProduct

E-Ring extended estrone derivatives: introduction of 2-phenylcyclopentenone to the estrone D-ring via an intermolecular Pauson–Khand reaction

2006

Abstract An expedient synthetic route to E-ring extended estrone derivatives is reported. Estrone-derived cyclopentenones were accessed by an intermolecular Pauson–Khand (PK) cycloaddition. It was found that electron donating and withdrawing substituents in the arylalkyne increased and decreased the yields of PK products, respectively. The stereochemistry of the products was elucidated by X-ray and NMR studies.

chemistry.chemical_compoundchemistryStereochemistryPauson–Khand reactionOrganic ChemistryDrug DiscoveryIntermolecular forceRegioselectivityEstroneBiochemistryCycloadditionTetrahedron Letters
researchProduct

RELATIONSHIP BETWEEN SECOND HAND SMOKE (SHS) EXPOSURE AND ATOPY IN SOCIAL DISADVANTAGED ASTHMATIC CHILDREN

2014

childrenscondhand smoke atopy asthma childrenatopyasthmascondhand smoke
researchProduct

Severe Perinatal Hypoxic-Ischemic Brain Injury Induces Long-Term Sensorimotor Deficits, Anxiety-Like Behaviors and Cognitive Impairment in a Sex-, Ag…

2019

Perinatal brain injury (PBI) leads to neurological disabilities throughout life, from motor deficits, cognitive limitations to severe cerebral palsy. Yet, perinatal brain damage has limited therapeutic outcomes. Besides, the immature brain of premature children is at increased risk of hypoxic/ischemic (HI) injury, with males being more susceptible to it and less responsive to protective/therapeutical interventions. Here, we model in male and female C57BL/6 mice, the impact of neonatal HI and the protective effects of neonatal handling (NH), an early life tactile and proprioceptive sensory stimulation. From postnatal day 1 (PND1, modeling pre-term) to PND21 randomized litters received either…

cognitionsensory stimulationCognitive NeurosciencePhysiologyBrain damageCorpus callosumlcsh:RC321-571Cerebral palsy03 medical and health sciencesBehavioral Neuroscience0302 clinical medicineAtrophyCognitionmedicinesexAnimal modelneonatal hypoxic ischemic injurylcsh:Neurosciences. Biological psychiatry. Neuropsychiatry030304 developmental biologyOriginal Research0303 health sciencesBehaviorSensory stimulation therapyNeocortexbusiness.industrybehaviorPutamenanimal modelNeophobiagender medicineNeonatal handlingmedicine.diseaseSensory stimulationmedicine.anatomical_structureNeuropsychology and Physiological PsychologyNeonatal hypoxic ischemic injuryneonatal handlingSexGender medicinemedicine.symptombusiness030217 neurology & neurosurgeryNeuroscienceFrontiers in Behavioral Neuroscience
researchProduct

L'ESTENSIONE DEI PERMESSI RETRIBUITI PER L'ASSISTENZA AI DISABILI NEL DECRETO “CURA ITALIA”

2020

Il contributo esamina le principali questioni interpretative e applicative scaturenti dalla disciplina di cui all'art. 24 d.l. n. 18 del 2020, in tema di permessi aggiuntivi per l'assistenza ai disabili in condizione di handicap grave. Particolare attenzione è dedicata ai limiti che consentono la fruizione dei benefici straordinari al personale sanitario, per il quale sono previste limitazioni che richiedono un complesso e assai incerto bilanciamento fra diritti fondamentali della persona.

congedi l. n. 104/1992 handicap grave covid-19 decreto cura italia d.l. n. 18/2020
researchProduct

L'évolution du régime de responsabilité du transporteur maritime de marchandises en droit togolais

2018

contrat de transport international de marchandises[SHS.DROIT] Humanities and Social Sciences/Lawlégislations maritimesresponsabilitéTogoTransporteur maritime de marchandisesRègles de Hambourg[SHS] Humanities and Social Sciencesrègles de Rotterdamobligations
researchProduct

Contrattualistica sportiva

2010

Il lavoro analizza la disciplina del contratto di lavoro sportivo, del contratto di sponsorizzazione, del contratto di merchandising e del contratto di vendita dei diritti televisivi

contratto di lavoro sportivo sponsorizzazione merchandising vendita dei diritti televisiviLavoro sportivo sponsorizzazione merchandising diritti televisiviSettore IUS/01 - Diritto Privato
researchProduct

Handicap et contre-transfert

2014

International audience

contre-transfert[SHS.PHIL] Humanities and Social Sciences/Philosophy[ SHS.PHIL ] Humanities and Social Sciences/Philosophy[SHS.PHIL]Humanities and Social Sciences/PhilosophyComputingMilieux_MISCELLANEOUShandicap
researchProduct

Geometrinen hahmottaminen sosiaalisena, vuorovaikutteisena ja kehollisena toimintana

2022

Matematiikan ja luonnontieteiden oppimista käsittelevässä tutkimuksessa on viime aikoina korostettu kehon, kognition ja vuorovaikutuksen läheistä yhteyttä. Tässä artikkelissa pohdimme, millä tavoin geometrinen hahmottaminen on sosiaalista, vuorovaikutteista ja materiaalien välittämää kehollista toimintaa. Tarkastelemme eräässä kouluajan ulkopuolella järjestetyssä STEAM-työpajassa kerättyä videoaineistoa keskustelunanalyysin menetelmin. Työpajassa alakouluikäiset oppilaat saivat tehtäväkseen koota pareittain jalkapallon geometrisen representaation 4DFrame-rakennussarjan muoviputkista ja -kiinnikkeistä. Tapaustutkimuksemme osoittaa, miten tämän kaltaisen ohjatun rakennustehtävän aikana katse,…

conversation analysisoppiminenmatematiikkamathematicskeskustelunanalyysiluonnontieteetperceptionhands-on workshopsSTEAM-opetusembodied learningsosiaalinen vuorovaikutusopetuskehollinen oppiminenArtikkeleitahahmottaminenkokemusoppiminenhahmottaminen STEAM-opetus geometria kehollinen oppiminen hands on -työpajat keskustelunanalyysigeometriaKasvatus
researchProduct

Anticipatory postural adjustments during joint action coordination

2019

International audience; There is a current claim that humans are able to effortlessly detect others’ hidden mental state by simply observing their movements and transforming the visual input into motor knowledge to predict behaviour. Using a classical paradigm quantifying motor predictions, we tested the role of vision feedback during a reach and load-lifting task performed either alone or with the help of a partner. Wrist flexor and extensor muscle activities were recorded on the supporting hand. Early muscle changes preventing limb instabilities when participants performed the task by themselves revealed the contribution of the visual input in postural anticipation. When the partner perfo…

coordinationPosturelcsh:MedicineActivationSocio-culturaleReaching MovementsArticleTimesocial behaviorCorticesMedical researchextensor muscleMotor controlLS5_1[SDV.MHEP.AHA]Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO]Posture coordination extensor muscle flexor muscle social behaviorlcsh:Scienceflexor muscleSupplementary Motor Arealcsh:RHandAcquisitionPremotorlcsh:QPerception[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]Load-Lifting Task[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
researchProduct