Search results for "Hand"

showing 10 items of 1364 documents

Combination of open field and elevated plus-maze: a suitable test battery to assess strain as well as treatment differences in rat behavior.

1998

Abstract 1. 1. A test battery consisting of a standard open field, an enriched open field and an elevated plus maze was used to study behavior in rats. 2. 2. Male rats of the strains PVG/OlaHsd (PVG) and Sprague-Dawely-Hsd (SPRD) (150–200g body wt) were used to assess interstrain differences as well as handling effects. In a subsequent experiment an other set of male PVG rats (150–200g body wt) treated either with diazepam or zolpidem was used to evaluate the test battery for pharmacological purposes. 3. 3. SPRD rats displayed higher motor activity levels and also higher levels of exploratory behavior than the PVG rats. In contrast plus-maze activity indicated more anxiety of SPRD than PVG …

Malemedicine.medical_specialtyZolpidemElevated plus mazemedicine.drug_classPyridinesMotor ActivityHandling PsychologicalAnxiolyticOpen fieldRats Sprague-DawleySpecies SpecificityInternal medicinemedicineAnimalsHypnotics and SedativesMaze LearningBiological PsychiatryPharmacologyAnalysis of VarianceDiazepamStrain (chemistry)Biological activityRats Inbred StrainsRatsZolpidemEndocrinologyAnesthesiaExploratory BehaviorSprDPsychologyDiazepammedicine.drugProgress in neuro-psychopharmacologybiological psychiatry
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Response to "The ulnar palmar perforator flap: Anatomical study and clinical application"

2014

Malemedicine.medical_specialtybusiness.industryulnar palmar perforator flapSettore MED/19 - Chirurgia PlasticaHandSurgical FlapsSurgeryFinger InjuriesHumansMedicineFemaleSurgerybusiness
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Metabolic and Functional Improvements in a Patient with Charcot-Marie-Tooth Disease Type 2 after EGCG Administration: A Case Report.

2021

Background and objectives: The aim of this study was to report a case of a patient with Charcot-Marie-Tooth disease type 2 (CMT2) treated with epigallocatechin gallate (EGCG) for 4 months in order to assess its therapeutic potential in CMT2. Materials and Methods: The study included a brother and a sister who have CMT2. The sister received 800 mg of EGCG for 4 months, while her brother received placebo for the same period of time. Both participants were assessed before and after daily administration by means of anthropometry; analysis of inflammatory and oxidation markers of interleukin-6 (IL-6) and paraoxonase 1 (PON1) in the blood sample; and motor tests: 2-min walk test (2MWT), 10-m walk…

Malemedicine.medical_specialtyepigallocatechin gallateCase ReportWalk TestDiseaseEpigallocatechin gallatePlaceboCatechinchemistry.chemical_compoundTooth diseaseCharcot-Marie-Tooth DiseaseInternal medicineMedicineHumansCharcot-Marie-Tooth disease type 2lcsh:R5-920IL-6biologyHand Strengthbusiness.industrymotor activityAryldialkylphosphataseParaoxonaseparaoxonase 1General MedicineAnthropometryPON1chemistryWalk testbiology.proteinFemalebusinesslcsh:Medicine (General)
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Psychomotor, Psychosocial and Reading Skills in Children with Amblyopia and the Effect of Different Treatments

2020

Amblyopia influences psychomotor and psychosocial skills, although not all studies are unanimous. Different treatments coexist, but the effect on those variables is not clear. This study aims to probe whether children with amblyopia have impairments in these areas and if different optometric treatments reduce them effectively. 50 children, diagnosed with amblyopia, and 33 without amblyopia participated in this study. Eye-hand coordination, psychosocial skills and reading abilities, were measured before and after three months of different treatments (patch, patch and near vision activities and perceptual learning). Results revealed lower scores in eye-hand coordination and some reading issue…

Malemedicine.medical_specialtygenetic structuresCognitive Neurosciencemedia_common.quotation_subjectBiophysicsExperimental and Cognitive PsychologyAudiologyAmblyopia050105 experimental psychologySocial Skills03 medical and health sciencesNear vision0302 clinical medicinePerceptual learningReading (process)medicineHumans0501 psychology and cognitive sciencesOrthopedics and Sports MedicineChildmedia_commonPsychomotor learningVision BinocularEye–hand coordination05 social scienceseye diseasesReadingChild PreschoolFemalePsychologyPsychosocialPsychomotor Performance030217 neurology & neurosurgeryReading skillsJournal of Motor Behavior
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Ventilation volumes with different self-inflating bags with reference to the ERC guidelines for airway management: comparison of two compression tech…

2000

The 1998 ERC-guidelines for airway-management recommend an tidal volume of 400-600 ml for adults undergoing CPR. As commercially available self-inflating bags were designed to meet former recommendations (800-1200 ml) we investigated how to meet the latest recommendations with these bags. We combined the head of a training manikin (Laerdal Medical) and a standard lung (VTTL; Michigan Instrument), adjusted to a physiological compliance and resistance. Volume was measured with a Wright spirometer (BOC). Seven self-inflating bags were investigated. Tests were carried out by ten people (five female and five male) for 5 min each using two different techniques. Technique 1: standard ventilation w…

Malemedicine.medical_specialtymedicine.medical_treatmentHand techniqueEmergency Nursinglaw.inventionlawTidal VolumeMedicineHumansTidal volumeVentilators Mechanicalbusiness.industryCompression (physics)Respiration ArtificialCardiopulmonary ResuscitationSurgeryVentilation (architecture)Practice Guidelines as TopicEmergency MedicineAirway managementFemaleOpen palm techniqueCardiology and Cardiovascular MedicinebusinessNuclear medicineSpirometerVolume (compression)Resuscitation
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Association between Obesity History and Hand Grip Strength in Older Adults-Exploring the Roles of Inflammation and Insulin Resistance as Mediating Fa…

2011

Background: To examine the association between obesity history and hand grip strength, and whether the association is partly explained by subclinical inflammation and insulin resistance. Methods:Data are from 2,021 men and women aged 55 years and older participating in the representative population-based Health 2000 Survey in Finland. Body mass and body height, maximal hand grip strength, C-reactive protein, and insulin resistance based on homeostasis model assessment (HOMA-IR) were measured in a health examination. Recalled weight at 20, 30, 40, and 50 years of age were recorded to obtain a hierarchical classification of obesity history. Obesity was defined as body mass index ≥ 30 kg/m2. R…

Malemedicine.medical_specialtyobesityAgingLogistic regressionBody Mass IndexGrip strengthInsulin resistanceSDG 3 - Good Health and Well-beingRisk FactorsInternal medicineHand strengthinsulin resistancemedicineHumansObesityProspective cohort studyFinlandAgedInflammationHand Strengthbusiness.industryMuscle strengthagingInsulin resistanceMiddle Agedmedicine.diseaseObesityConfidence intervalBody HeightC-Reactive ProteininflammationPhysical therapyJournal of Gerontology: MEDICAL SCIENCES/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingFemaleGeriatrics and GerontologybusinessBody mass index
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Three-year (2017-2019) activity report of the Replantation Service for hand amputations in Poland

2021

W pracy przedstawiono podsumowanie działalności Serwisu Replantacyjnego dla amputacji rąk w Polsce w latach 2017-2019. W analizowanym okresie, do Serwisu zgłoszono 551 przypadków amputacji i innych rozległych urazów kończyn górnych, z czego 330 zaakceptowano do operacji, a w 221 przypadkach, z różnych powodów odmówiono przyjęcia. Wśród 330 przyjętych było 165 (50%) amputacji całkowitych, 131 (40%) prawie całkowitych i 34 (10%) inne, ciężkie, zagrażające utratą kończyny urazy. W przeważającej liczbie ofiarami byli mężczyźni w młodym i średnim wieku. Najwięcej było amputacji kilku palców i kciuków - 251 (76%), następnie amputacji na poziomie śródręcza - 30 (9%), przedramienia - 23 (7%) i nadg…

Malemedicine.medical_specialtyreplantacja rękimedicine.medical_treatmentWristRevascularizationmikrochirurgiaAmputation Surgicalhand replantationAmputation TraumaticForearmwyniki leczeniamedicineHumansSurvival ratebusiness.industryHand InjuriesGeneral MedicinemicrosurgeryMicrosurgerySurgeryAmputated extremitymedicine.anatomical_structureAmputationReplantationReplantationSurgeryPolandbusinessoutcome measurementPolski Przegląd Chirurgiczny
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Global trends of hand and wrist trauma: A systematic analysis of fracture and digit amputation using the Global Burden of Disease 2017 Study

2020

BackgroundAs global rates of mortality decrease, rates of non-fatal injury have increased, particularly in low Socio-demographic Index (SDI) nations. We hypothesised this global pattern of non-fatal injury would be demonstrated in regard to bony hand and wrist trauma over the 27-year study period.MethodsThe Global Burden of Diseases, Injuries, and Risk Factors Study 2017 was used to estimate prevalence, age-standardised incidence and years lived with disability for hand trauma in 195 countries from 1990 to 2017. Individual injuries included hand and wrist fractures, thumb amputations and non-thumb digit amputations.ResultsThe global incidence of hand trauma has only modestly decreased since…

Malemedicine.medical_treatmentHandsWristburden of diseaseGlobal HealthGlobal Burden of Disease0302 clinical medicineLIFE EXPECTANCY1506030212 general & internal medicinehand injuryPOPULATIONOriginal Research030222 orthopedicseducation.field_of_studyIncidenceIncidence (epidemiology)Hand InjuriesWristsWristWrist Injuries3142 Public health care science environmental and occupational health3. Good healthPREVALENCEmedicine.anatomical_structureFemaleQuality-Adjusted Life YearsTERRITORIESdescriptive epidemiologymedicine.medical_specialtyPopulation195 COUNTRIESThumbAmputation Surgical03 medical and health sciencesAGEmedicineTraumasHumanseducationHand injurySEX-SPECIFIC MORTALITYbusiness.industryPublic Health Environmental and Occupational HealthEASTERN-EUROPEAmputationsmedicine.diseaseNumerical digitAmputationHEALTH-CAREPhysical therapyLife expectancyINJURIESbusinessFractures
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Assessment of construct validity of the Finnish versions of the Disabilities of Arm, Shoulder and Hand Instrument and the Michigan Hand Outcomes Ques…

2020

Abstract Study Design Cross-sectional study. Introduction There is a lack of information on the measurement properties of patient-reported upper extremity instruments and their association to health-related quality of life (HRQoL). Purpose of the Study This study aimed to examine and compare the measurement properties and construct validity of the Disabilities of Arm, Shoulder, and Hand (DASH) Instrument and the Michigan Hand Questionnaire (MHQ) using a heterogeneous sample of patients with hand and wrist problems. Methods Two hundred fifty consecutive patients visiting a general orthopedic outpatient clinic due to various hand/wrist problems were invited to participate in the study. A tota…

Malemusculoskeletal diseases030506 rehabilitationmedicine.medical_specialtyVisual Analog ScaleVisual analogue scalefyysinen toimintakykyPhysical Therapy Sports Therapy and Rehabilitationupper limbkädetUpper ExtremityDisability Evaluation03 medical and health sciences0302 clinical medicineQuality of lifeSurveys and QuestionnairesDashupper extremitymedicineHumansOutpatient clinictoimintarajoitteetFinlandPROMfunctionHand Strengthbusiness.industryRehabilitationConstruct validityMiddle AgedhumanitiesCross-Sectional Studiesmedicine.anatomical_structuredisabilityScale (social sciences)mittarit (mittaus)Orthopedic surgeryQuality of LifePhysical therapyUpper limbFemale0305 other medical sciencebusinesshuman activities030217 neurology & neurosurgeryJournal of Hand Therapy
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A new heterozygous mutation (D196N) in the Gs alpha gene as a cause for pseudohypoparathyroidism type IA in a boy who had gallstones

2011

Background Pseudohypoparathyroidism (PHP) is characterized by hypocalcemia and hyperphosphatemia in association with an increased secretion of parathyroid hormone (PTH) due to decreased target tissue responsiveness to PTH. Patients with PHP type Ia are not only resistant to PTH, but also to other hormones that bind to receptors coupled to stimulatory G protein (Gsalpha). PHP Ia and Albright hereditary osteodystrophy (AHO) are caused by a reduced activity of the Gsalpha protein. Heterozygous inactivating Gs alpha (GNAS) gene mutations have been identified in these patients. Methods We studied a boy with PHP Ia. During follow-up the patient developed elevated liver enzyme serum levels and abd…

Malemusculoskeletal diseasesHeterozygotemedicine.medical_specialtyErythrocytesFoot Deformities CongenitalEndocrinology Diabetes and MetabolismMutation MissenseParathyroid hormoneGallstonesGene mutationHyperphosphatemiaEndocrinologyInternal medicineChromograninsGTP-Binding Protein alpha Subunits GsGNAS complex locusHumansMedicineMissense mutationnatural sciencesAmino Acid SequenceChildConserved SequencePseudohypoparathyroidismBase SequenceSequence Homology Amino Acidbiologybusiness.industryDNAExonsGallstonesmedicine.diseasePedigreeCholesterolEndocrinologyAmino Acid SubstitutionPseudohypoparathyroidismPediatrics Perinatology and Child Healthbiology.proteinbusinessHand Deformities CongenitalHormoneJournal of Pediatric Endocrinology and Metabolism
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