Search results for "Hardy"

Modeling of Hardy-Weinberg Equilibrium Using Dynamic Random Networks in an ABM Framework

2023

Hardy-Weinberg equilibrium is the fundamental principle of population genetics. In this article, we present a new NetLogo model called “Hardy-Weinberg Basic model v 2.0”, characterized by a strict adherence to the original assumptions made by Hardy and Weinberg in 1908. A particularly significant feature of this model is that the algorithm does not make use of the binomial expansion formula. Instead, we show that using a procedure based on dynamic random networks, diploid equilibrium can be achieved spontaneously by a population of agents reproducing sexually in a Mendelian fashion. The model can be used to conduct simulations with a wide range of initial population sizes and genotype distr…

Un approccio bayesiano per lo studio dell’associazione gene-ambiente in assenza di equilibrio di Hardy-Weinberg in un contesto multivariabile: studio…

2009

Testing for goodness rather than lack of fit of an X–chromosomal SNP to the Hardy-Weinberg model

2019

The problem of checking the genotype distribution obtained for some diallelic marker for compatibility with the Hardy-Weinberg equilibrium (HWE) condition arises also for loci on the X chromosome. The possible genotypes depend on the sex of the individual in this case: for females, the genotype distribution is trinomial, as in the case of an autosomal locus, whereas a binomial proportion is observed for males. Like in genetic association studies with autosomal SNPs, interest is typically in establishing approximate compatibility of the observed genotype frequencies with HWE. This requires to replace traditional methods tailored for detecting lack of fit to the model with an equivalence test…

Hardy’s inequality and the boundary size

2002

We establish a self-improving property of the Hardy inequality and an estimate on the size of the boundary of a domain supporting a Hardy inequality.

Intrinsic Hardy–Orlicz spaces of conformal mappings

2014

We define a new type of Hardy-Orlicz spaces of conformal mappings on the unit disk where in place of the value |f(x)| we consider the intrinsic path distance between f(x) and f(0) in the image domain. We show that if the Orlicz function is doubling then these two spaces are actually the same, and we give an example when the intrinsic Hardy-Orlicz space is strictly smaller.

In between the inequalities of Sobolev and Hardy

2016

We establish both sufficient and necessary conditions for the validity of the so-called Hardy–Sobolev inequalities on open sets of the Euclidean space. These inequalities form a natural interpolating scale between the (weighted) Sobolev inequalities and the (weighted) Hardy inequalities. The Assouad dimension of the complement of the open set turns out to play an important role in both sufficient and necessary conditions. peerReviewed

Muckenhoupt $A_p$-properties of distance functions and applications to Hardy-Sobolev -type inequalities

2017

Let $X$ be a metric space equipped with a doubling measure. We consider weights $w(x)=\operatorname{dist}(x,E)^{-\alpha}$, where $E$ is a closed set in $X$ and $\alpha\in\mathbb R$. We establish sharp conditions, based on the Assouad (co)dimension of $E$, for the inclusion of $w$ in Muckenhoupt's $A_p$ classes of weights, $1\le p<\infty$. With the help of general $A_p$-weighted embedding results, we then prove (global) Hardy-Sobolev inequalities and also fractional versions of such inequalities in the setting of metric spaces.

Noncommutative Davis type decompositions and applications

2018

We prove the noncommutative Davis decomposition for the column Hardy space $\H_p^c$ for all $0<p\leq 1$. A new feature of our Davis decomposition is a simultaneous control of $\H_1^c$ and $\H_q^c$ norms for any noncommutative martingale in $\H_1^c \cap \H_q^c$ when $q\geq 2$. As applications, we show that the Burkholder/Rosenthal inequality holds for bounded martingales in a noncommutative symmetric space associated with a function space $E$ that is either an interpolation of the couple $(L_p, L_2)$ for some $1<p<2$ or is an interpolation of the couple $(L_2, L_q)$ for some $2<q<\infty$. We also obtain the corresponding $\Phi$-moment Burkholder/Rosenthal inequality for Orlicz functions that…

Fractional Hardy-Sobolev type inequalities for half spaces and John domains

2018

As our main result we prove a variant of the fractional Hardy-Sobolev-Maz'ya inequality for half spaces. This result contains a complete answer to a recent open question by Musina and Nazarov. In the proof we apply a new version of the fractional Hardy-Sobolev inequality that we establish also for more general unbounded John domains than half spaces.

Vector-Valued Hardy Spaces

2019

Given a Banach space X, we consider Hardy spaces of X-valued functions on the infinite polytorus, Hardy spaces of X-valued Dirichlet series (defined as the image of the previous ones by the Bohr transform), and Hardy spaces of X-valued holomorphic functions on l_2 ∩ B_{c0}. The chapter is dedicated to study the interplay between these spaces. It is shown that the space of functions on the polytorus always forms a subspace of the one of holomorphic functions, and these two are isometrically isomorphic if and only if X has ARNP. Then the question arises of what do we find in the side of Dirichlet series when we look at the image of the Hardy space of holomorphic functions. This is also answer…