Search results for "Hazard"

Timing, Complications, and Safety of Tracheotomy in Critically Ill Patients With COVID-19

2021

Importance: The current coronavirus disease 2019 (COVID-19) pandemic has led to unprecedented needs for invasive ventilation, with 10% to 15% of intubated patients subsequently requiring tracheotomy. Objective: To assess the complications, safety, and timing of tracheotomy performed for critically ill patients with COVID-19. Design, Setting, and Participants: This prospective cohort study assessed consecutive patients admitted to the intensive care unit (ICU) who had COVID-19 that required tracheotomy. Patients were recruited from March 16 to April 10, 2020, at a tertiary referral center. Exposures: A surgical tracheotomy was performed for all patients following recommended criteria for use…

Multi-method evaluation of denudation rates in small mediterranean catchments

2015

The paper presents the results of the research tasks of the Quantitative Geomorphology Working Group (of the Italian Association of Physical Geography and Geomorphology) focused on multi-method evaluation of denudation rates in small catchments of Italy. Several study areas are compared with the goal of quantifying the morphodynamic evolution in different response times and with traditional and innovative techniques. The final aims are the direct erosion monitoring, the geomorphic analysis for the comprehension of drainage basin morphodynamics, up to the geomorphological hazard evaluation. The catchments are key Mediterranean areas particularly sensitive to climatic and anthropic modificati…

2017

From 2000 to 2015, tsunamis and storms killed more than 430,000 people worldwide and affected a further >530 million, with total damages exceeding US$970 billion. These alarming trends, underscored by the tragic events of the 2004 Indian Ocean catastrophe, have fueled increased worldwide demands for assessments of past, present, and future coastal risks. Nonetheless, despite its importance for hazard mitigation, discriminating between storm and tsunami deposits in the geological record is one of the most challenging and hotly contended topics in coastal geoscience. To probe this knowledge gap, we present a 4500-year reconstruction of “tsunami” variability from the Mediterranean based on str…

Using topographical attributes to evaluate gully erosion proneness (susceptibility) in two mediterranean basins: advantages and limitations

2015

Empirical multivariate predictive models represent an important tool to estimate gully erosion susceptibility. Topography, lithology, climate, land use and vegetation cover are commonly used as input for these approaches. In this paper, two multivariate predictive models were generated for two gully erosion processes in San Giorgio basin (Italy) and Mula River basin (Spain) using only topographical attributes as independent variables. Initially, nine models (five for San Giorgio and four for Mula) with pixel sizes ranging from 2 to 50 m were generated, and validation statistics were calculated to estimate the optimal pixel size. The best models were selected based on model performance using…

Mapping temporally-variable exposure to flooding in small Mediterranean basins using land-use indicators

2011

Abstract This article deals with mapping exposure (or external vulnerability) to flood risk in two typical Mediterranean ephemeral streams: the Barranco de Carraixet and the Rambla de Poyo. The floodplains of both streams are within the metropolitan area of the city of Valencia (Spain’s third largest city). Following the Mediterranean model, they are very fertile areas (with intense periurban and highly productive agriculture) which have recently absorbed the great urban expansion of the metropolis. Hydrologically these basins remain dry for most of the year, but become particularly dangerous during flash-flood events. They generate a risk pattern highly dependent on exposure since, in gene…

Pegylated liposomal doxorubicin in the management of ovarian cancer

2014

Ovarian cancer is the leading cause of death among gynecological tumors. Carboplatin/paclitaxel represents the cornerstone of front-line treatment. Instead, there is no consensus for management of recurrent/progressive disease, in which pegylated liposomal doxorubicin (PLD) ± carboplatin is widely used. We performed a systematic review and metaanalysis to evaluate impact of PLD-based compared with no-PLD-based regimens in the ovarian cancer treatment. Data were extracted from randomized trials comparing PLD-based treatment to any other regimens in the January 2000-January 2013 time-frame. Study end-points were overall survival (OS), progression free survival (PFS), response rate (RR), CA125…

Walnut Consumption, Plasma Metabolomics, and Risk of Type 2 Diabetes and Cardiovascular Disease

2021

BACKGROUND: Walnut consumption is associated with lower risk of type 2 diabetes (T2D) and cardiovascular disease (CVD). However, it is unknown whether plasma metabolites related to walnut consumption are also associated with lower risk of cardiometabolic diseases. OBJECTIVES: The study aimed to identify plasma metabolites associated with walnut consumption and evaluate the prospective associations between the identified profile and risk of T2D and CVD. METHODS: The discovery population included 1833 participants at high cardiovascular risk from the PREvención con DIeta MEDiterránea (PREDIMED) study with available metabolomics data at baseline. The study population included 57% women (baseli…

Incentive Schemes, Private Information and the Double-Edged Role of Competition for Agents

2013

This paper examines the effect of imperfect labor market competition on the efficiency of compensation schemes in a setting with moral hazard and risk-averse agents, who have private information on their productivity. Two vertically differentiated firms compete for agents by offering contracts with fixed and variable payments. The superior firm employs both agent types in equilibrium, but the competitive pressure exerted by the inferior firm has a strong impact on contract design: For high degrees of vertical differentiation, i.e. low competition, low-ability agents are under-incentivized and exert too little effort. For high degrees of competition, high-ability agents are over-incentivized…

Are you a good employee or simply a good guy? Influence costs and contract design

2013

We develop a principal–agent model with a moral hazard problem in which the principal has access to a hard signal (the level of output) and a soft behavioral signal (the supervision signal) about the agent's level of effort. In our model, the agent can initiate influence activities and manipulate the behavioral signal. These activities are costly for the principal as they detract the agent from the productive task. We show that the agent's ability to manipulate the behavioral signal leads to low-powered incentives and increases the cost of implementing the efficient equilibrium as a result. Interestingly, the fact that manipulation activities entail productivity losses may lead to the desig…

MEMS-Based System for Structural Health Monitoring and Earthquake Observation in Sicily

2021

The implementation of systems for Structural Health Monitoring and Earthquake Observation is increasing in the last years owing to the development of new technologies which enable low-cost and small-size devices to be installed in large-scale or high-density applications. This paper introduces the implementation of monitoring systems, either for structural health assessment and earthquake observation. The applications are based in Sicily (Italy), a region characterized by a high seismic hazard and where the buildings are often old and vulnerable. The system relies on a MEMS (Micro Electro-Mechanical Systems) sensor, a 3-axial accelerometer which has been specifically selected in order to en…