Search results for "Hdl"
showing 8 items of 298 documents
CETP levels rather than polymorphisms as markers of coronary risk: Healthy athlete with high HDL-C and coronary disease—effectiveness of probucol
2006
Establishing cut-off values for apolipoprotein B and non-HDL-C according to LDL-C values in a South European population
2012
SUMMARY Background: Low-density lipoprotein cholesterol (LDL-C) remains the primary target of therapy in most strategies of dyslipidaemia management focused on cardiovascular disease prevention. Different guidelines have identified specific LDL-C cut-off points as targets for therapeutic intervention. Many clinical situations characterised by dyslipidaemia and elevated triglycerides are common in our environment and in overall industrialised countries. Thus, lipid goals based only on LDL-C could misclassify an important percentage of subjects. The objective of the present study was to establish cut-off point values for apoB and non-HDL-C in relation to the identified LDL-C cut-off points fo…
Triglycerides, HDL cholesterol and atherogenic dyslipidaemia in the 2019 European guidelines for the management of dyslipidaemias.
2019
In general, both European and American clinical guidelines have addressed the management of atherogenic dyslipidaemia in an unconvincing and even superficial way, largely because of the available therapeutic limitations. Consequently, this type of dyslipidaemia is underdiagnosed, under-treated, and under-controlled. Given the recent presentation of the 2019 guidelines of the European Atherosclerosis Society and the European Society of Cardiology on the management of dyslipidaemias, it seems appropriate to examine its position with respect to atherogenic dyslipidaemia and/or its main components, the increase in triglyceride-rich lipoproteins, and the decrease of high-density lipoprotein chol…
Constitutive androstane receptor activation stimulates faecal bile acid excretion and reverse cholesterol transport in mice.
2010
The constitutive androstane receptor (CAR) is a nuclear receptor expressed in the liver and involved in xenobiotic metabolism. The aim of this study was to assess whether pharmacological CAR activation could affect neutral sterol and bile acid elimination under conditions of cholesterol overload.Wild type, Car-/-, ApoE-/-, and low-density lipoprotein receptor (Ldlr)-/- mice fed a western-type diet were treated with the CAR agonist TCPOBOP.CAR activation was associated with a decrease in faecal cholesterol output related to the repression of the Abcg5/g8 cholesterol transporters. In contrast, TCPOBOP treatment induced a marked increase (up to three fold, p0.01) in the elimination of faecal b…
Positive association of high-density lipoprotein cholesterol with lumbar and femoral neck bone mineral density in postmenopausal women.
2021
Abstract Objective Experimental studies suggest that lipids affect bone metabolism. We aimed to elucidate whether lipid levels are associated with bone mineral density (BMD) in a cohort of postmenopausal women. Design A cross-sectional study of participants in the Chronic Ailment Reduction after MENopause (CARMEN) cohort. Women underwent assessment of clinical and analytical parameters, including fasting lipid levels. BMD was assessed at both lumbar spine and hip. Homogeneity in the cohort was optimized by filtering out a series of confounding variables with a known impact on bone. Main outcome measures Association of BMD at lumbar spine and femoral neck with lipid levels. Results A total o…
Ravinnon vaikutus happo-emästasapainoon ja rasva-aineenvaihduntaan levossa sekä kestävyyskuormituksessa eri-ikäisillä miehillä ja naisilla
2012
Johdanto. On todettu, että ruokavaliolla voidaan vaikuttaa elimistön happo-emästasapainoon. Elimistön happamuus on yhteydessä fyysiseen suorituskykyyn, mutta lisäksi mm. diabeteksen, sepelvaltimotaudin, keskivartalolihavuuden ja syöpien riskiin. pH:n lasku eli happamuuden lisääntyminen heikentää lihasten voimantuottokykyä ja välittömän energianlähteen adenosiinitrifosfaatin (ATP) muodostumista ja käyttöä. Kasvispitoisen ruokavalion on todettu nostavan virtsan pH:ta ja lisäksi laskevan veren kokonaiskolesteroli- sekä LDL (low density lipoprotein) -kolesterolin pitoisuuksia. Tutkimuksen tarkoitus. Tämän tutkimuksen tarkoituksena oli selvittää normaaliproteiinisen kasvisravinnon (EMÄS, PRAL 0)…
Supercooled Water Confined in a Silica Xerogel: Temperature and Pressure Dependence of Boson Peak and of Mean Square Displacements
2013
A silica xerogel can be obtained from an alcoxide precursor (TMOS, tetramethylortosilcate) via the sol-gel method: TMOS hydrolysis and subsequent polycondensation yields a solid, disordered, porous SiO2 matrix (average pore dimensions ~20Å). Inside the pores water is trapped and the hydration level h=gr[H2O]/gr[SiO2] can be easily controlled. The presence and temperature dependence of the boson peak (BP) in xerogel confined supercooled water was studied with inelastic neutron scattering (spectrometer IN6 at ILL, Grenoble) in xerogel samples having h=0.4 and h=0.2. After careful subtraction of the contributions arising from the matrix and from quasi-elastic scattering, the BP contribution wa…
Reāla laika stereo attēlu korekcija, izmantojot programmējamos loģikas masīvus
2018
Bakalaura darba mērķis ir veikt lēcas radiālo kropļojumu labošanas un attēlu izlīdzināšanas algoritmu izpēti, kā arī veikt to implementāciju programmējamos loģikas masīvos, kā sastāvdaļu no stereo redzes sistēmas, kas paredzēta attēla dziļuma karšu veidošanai. Autors aprakstīs risinājumu algoritmus un, lai demonstrētu Bakalaura darba ietvaros izvirzītās problēmas iespējamo risinājumu, izmantojot programmējamos loģikas masīvus, darba autors veiks praktiskās daļas izstrādi, kas sastāvēs no lēcas radiālo kropļojumu labošanas un attēlu izlīdzināšanas algoritmu implementācijām VHDL valodā. Darbs sastāv no 55 lappusēm, 18 attēliem, 2 tabulām un 7 pielikumiem. Darbā izmantoti 23 literatūras avoti.