Search results for "Head"

showing 10 items of 1640 documents

Dental approach of orofacial pain in head and neck cancer patients

2018

Background Orofacial pain (OFP) is an undesirable sensation frequently associated with head and neck cancer (HNC) and its treatment. OFP negatively impacts the quality of life of oncological patients. The approach to OFP diagnosis and management can differ if the patient visits a dentist or physician. The aim of this study was to present a case series of HNC with OFP managed by a dentist team and to discuss its role in the management of OFP. Material and methods We recruited twenty-two adult patients with OFP and previous diagnosis of HNC referred to an academic dental clinic from 2015 to 2017. Results Nociceptive was more frequent than mixed and neuropathic pain, however 54,4% of the cases…

Orofacial painmedicine.medical_specialtyOral Medicine and PathologyAdult patientsbusiness.industryResearchHead and neck cancer030206 dentistry:CIENCIAS MÉDICAS [UNESCO]medicine.disease03 medical and health sciences0302 clinical medicineDental clinic030220 oncology & carcinogenesisInternal medicineUNESCO::CIENCIAS MÉDICASNeuropathic painSensationmedicinemedicine.symptombusinessHead and neckGeneral DentistryJournal of Clinical and Experimental Dentistry
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Effectiveness and Duration of Plantar Pressure Off-loading by Two Designs of Felt Padding: A Preliminary Study.

2019

Background: The aim of this study was to observe the pressure changes in the felt padding used to off-load pressure from the first metatarsal head, the effects obtained by different designs, and the loss of effectiveness over time. Method: With a study population of 17 persons, two types of 5-mm semicompressed felt padding were tested: one was C-shaped, with an aperture cutout at the first metatarsophalangeal joint, and the other was U-shaped. Pressures on the sole of the foot were evaluated with a platform pressure measurement system at three time points: before fitting the felt padding, immediately afterward, and 3 days later. Results: In terms of decreased mean pressure on the first met…

OrthodonticsMaleMetatarsophalangeal JointAdolescentbusiness.industryFootPlantar pressureFirst metatarsalFoot OrthosesGeneral MedicineEquipment DesignWalkingMiddle AgedPaddingYoung AdultDuration (music)PressureMedicineHead (vessel)HumansFemalebusinessFoot OrthosesMetatarsal BonesJournal of the American Podiatric Medical Association
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Waiting for a head count

1997

OrthodonticsMultidisciplinaryHead (vessel)PsychologyNature
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Frontal Diameter of the Tibia Head: A Comparison of Results from Computed Tomography and Anthropometric Measurements

2009

Orthodonticsmedicine.medical_specialtymedicine.diagnostic_testbusiness.industrymedicineHead (vessel)Computed tomographyTibiaAnthropometrybusinessSurgery
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Placchetta a rilievo con testa maschile

2019

Studio di una lamina di osso con una testa maschile del Museo Archeologico Regionale "A. Salinas" di Palermo. A study of a little bone plate with a male head of the Regional Archaeological Museum "A. Salinas" in Palermo.

Osso piccola lamina testa maschile Museo "A. Salinas"Settore L-ANT/07 - Archeologia ClassicaBone Little plate Male head Museum "A. Salinas"
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A rare case of peri-implant distal radius fracture☆

2021

A peri-implant fracture near the volar plate of distal radius represent a very rare injury. The main factor of this lesion is high energy trauma on the wrist. We report a case of a 61-year-old woman with a peri-implant fracture located just proximally to the plate and a fracture of the ulnar head that occurred after a simple fall. The patient was surgically treated by plate and screws removal. The fracture was fixed using a longer volar plate for the radial fracture and a plate for the head ulnar fracture. Different factors such as osteoporosis, BMI and screw position could influence the fracture pattern. However, considering growing use of plates for distal radius fracture fixation, the fr…

Osteoporosislcsh:SurgeryUlnar headCase ReportWristCritical Care and Intensive Care MedicinePeri-implant radius fracture03 medical and health sciencesFixation (surgical)0302 clinical medicineRare caseSettore MED/33 - Malattie Apparato LocomotoreMedicineOrthopedics and Sports MedicineWrist fractureOrthodontics030222 orthopedicsScrew positionbusiness.industry030208 emergency & critical care medicinelcsh:RD1-811medicine.diseaseRadius and ulna fracturebody regionsmedicine.anatomical_structureRadius hardware substitutionEmergency MedicineDistal radius fractureImplantbusinessTrauma Case Reports
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Periodontal therapy for patients before and after radiotherapy : a review of the literature and topics of interest for clinicians

2018

Background To review and discuss important topics regarding periodontal treatment pre- and post-radiotherapy for head and neck cancer in human patients; to discuss the references for adequate techniques, the appropriate moment for tooth extractions and periodontal management; and to discuss the prevention of osteoradionecrosis. Material and Methods Thirty-nine studies including original studies, randomized clinical trials (RCTs) and reviews were searched in online databases MEDLINE (PubMed) and the Cochrane library. No year of publication restriction was applied. Results Language was restricted to English, and the following Medical Subject Heading terms were used: radiotherapy, radiation th…

Osteoradionecrosismedicine.medical_treatmentMEDLINEDentistryReviewCochrane Librarylaw.invention03 medical and health sciences0302 clinical medicineScaling and root planingRandomized controlled triallawmedicineHumansDental CareGeneral DentistryPeriodontal DiseasesOral Medicine and Pathologybusiness.industryHead and neck cancer030206 dentistrymedicine.disease:CIENCIAS MÉDICAS [UNESCO]Radiation therapyOtorhinolaryngologyDental extractionOsteoradionecrosisHead and Neck Neoplasms030220 oncology & carcinogenesisUNESCO::CIENCIAS MÉDICASSurgerybusiness
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Studie zur intraarteriellen Mono- und Polychemotherapie von Mundh�hlen- und Oropharynxkarzinomen: Methotrexat (MTX) im Vergleich zur Kombination Vinc…

1982

In einer vergleichenden Studie wurde bei Karzinomen der Mundhohle und des Oropharynx der zytostatische Effekt einer intraarteriellen Monotherapie mit Methotrexat (MTX) einer Polychemotherapie mit Vincristin-Methotrexat-Bleomycin-Cisplatin (VMBP) gegenubergestellt.

Otorhinolaryngologybusiness.industryHead and neck surgeryMedicineGeneral MedicinebusinessNuclear medicineArchives of Oto-Rhino-Laryngology
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MCC1019, a selective inhibitor of the Polo-box domain of Polo-like kinase 1 as novel, potent anticancer candidate

2019

Polo-like kinase (PLK1) has been identified as a potential target for cancer treatment. Although a number of small molecules have been investigated as PLK1 inhibitors, many of which showed limited selectivity. PLK1 harbors a regulatory domain, the Polo box domain (PBD), which has a key regulatory function for kinase activity and substrate recognition. We report on 3-bromomethyl-benzofuran-2-carboxylic acid ethyl ester (designated: MCC1019) as selective PLK1 inhibitor targeting PLK1 PBD. Cytotoxicity and fluorescence polarization-based screening were applied to a library of 1162 drug-like compounds to identify potential inhibitors of PLK1 PBD. The activity of compound MC1019 against the PLK1…

PBD Polo box domainMTD maximal tolerance doseCDC25 cell division cycle 25HIF-1α hypoxia-inducible factor 1 αMST microscale thermophoresisIC50 50% inhibition concentrationMFP M phase promoting factorPARP-1 poly(ADP-ribose) polymerase-10302 clinical medicineFOXO forkhead box ONec-1 necrostatin 1CDC2 cell division cycle protein 2 homologGeneral Pharmacology Toxicology and PharmaceuticsMitotic catastropheCDK cyclin-dependent kinase0303 health sciencesChemistryPolo-like kinaseMono-targeted therapyCell cycleBUBR1 budding uninhibited by benzimidazole-related 1Polo box domain030220 oncology & carcinogenesisPLK1 Polo-like kinaseNecroptosisSpindle damagePLK1IHC immunohistochemistryOriginal articleNecroptosisCell cyclePLK1APC/C anaphase-promoting complex/cyclosomePLK3ABC avidin-biotin complexPI propidium iodide03 medical and health sciencesFBS fetal bovine serumPDB Protein Data BankKd the dissociation constantKinase activity030304 developmental biologyAkt/PKB signaling pathwayCell growthlcsh:RM1-950LC3 light chain 3lcsh:Therapeutics. PharmacologyCancer researchDAPKs death-associated protein kinase3-MA 3-methyladenineDAPI 4′6-diamidino-2-phenylindoleSAC spindle assembly checkpointActa Pharmaceutica Sinica B
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Is 2-deoxy-2-[(18)F]fluoro-D-glucose PET/CT acquisition from the upper thigh to the vertex of skull useful in oncological patients?

2015

Aim:To assess whether performing routinely 2-deoxy-2-[18F]fluoro-D-glucose PET/CT (18FDG PET/CT) scanfrom the upper thigh to the vertex of skull is clinically relevant. Materials and Methods: 3502 (1634 female; mean-age 60+16) consecutive patients undergoing 18 FDG PET/CT were retrospectively analyzed. Patients were divided in 10 groups according to primar y malignancy. Chi-square analysis was used to assess differences among proportions. A p value < 0.05 was considered significant. Results: 18 FDG PET/CT was positive in head district in 130/3502 (3,7%) patients. In all patients lesions were unknown before PET/CT examination. PET/CT showed 158 positive brain/head uptake in the 130 patients.…

PET/CTbrainArticlesheadPET/CT; brain; head; whole-body acquisitionwhole-body acquisitionTranslational medicine @ UniSa
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