Search results for "Healthy subjects"

showing 10 items of 193 documents

Assessment of corneal morphological changes induced by the use of daily disposable contact lenses.

2015

To assess the effect of different disposable soft contact lenses upon corneal thickness, and upon anterior and posterior corneal curvatures using a dual-Scheimpflug imaging based device.Twenty-eight young, healthy subjects wore four different types of daily disposable soft contact lenses on four different days: Dailies Total1, Proclear 1 Day, Clariti 1-Day and 1-Day Acuvue Moist. The lenses had different material and water content. Pachymetry maps and keratometry values were obtained using the Galilei G4 twice a day: one before putting the lens on and one after an eight-hour period of contact-lens wear. Measurements were also recorded without any contact lenses being worn during a day.Clari…

AdultMaleVisual Acuitylaw.inventionCorneaYoung AdultlawMyopiaMedicineHumansDisposable EquipmentKeratometerCorneal curvaturebusiness.industryHealthy subjectsCorneal TopographyGeneral MedicineEquipment DesignContact Lenses Hydrophiliceye diseasesContact lensLens (optics)OphthalmologyOptometryDaily disposableFemalesense organsThickeningbusinessOptometryFollow-Up StudiesContact lensanterior eye : the journal of the British Contact Lens Association
researchProduct

Reference interval by the indirect approach of serum thyrotropin (TSH) in a Mediterranean adult population and the association with age and gender.

2019

Abstract Background The serum concentration of thyrotropin (TSH) represents a first-line test in diagnostic algorithms. The estimation of TSH reference intervals (RIs) is still a matter of debate due to the high prevalence of subclinical disease making difficult the definition of truly healthy subjects. The aim of this study was to estimate TSH RIs in healthy subjects and to evaluate the effect of age and gender on TSH concentration. Methods Forty-four thousand one hundred and fifty-six TSH data were collected between July 2012 and April 2018 at the Department of Laboratory Medicine, University-Hospital, Palermo. Common and sex-specific RIs were estimated by Arzideh’s indirect method after …

AdultMaleendocrine systemThyroid Hormonesendocrine system diseasesAdolescentClinical BiochemistryAdult populationThyroid GlandPhysiologyThyrotropin030209 endocrinology & metabolismThyroid Function Testslaboratory information systemAge and gender03 medical and health sciences0302 clinical medicineSex FactorsReference ValuesPrevalenceMedicineHumansthyroid diseaseHigh prevalenceTSHbusiness.industryMediterranean RegionThyroid diseaseBiochemistry (medical)Healthy subjectsAge FactorsDiagnostic algorithmsGeneral Medicinereference intervalMiddle Agedmedicine.diseaseindirect methodHealthy VolunteersReference intervalsThyroxine030220 oncology & carcinogenesisFree triiodothyronineTriiodothyronineBiological AssayFemalebusinesshormones hormone substitutes and hormone antagonistsClinical chemistry and laboratory medicineReferences
researchProduct

Gender differences on oxidative stress markers and complement component C3 plasma values after an oral unsaturated fat load test

2020

Abstract Objective Post-prandial lipaemia (PL), oxidative stress (OS), and complement component C3 (C3) values are related to the atherosclerosis process. The post-prandial response of C3 after an oral fat load test (OFLT) using unsaturated fat is poorly addressed. The aim of this study was to analyze and compare the post-prandial response of OS markers and C3 values in men and women after an OFLT using unsaturated fat. Methods The study included a total of 22 healthy subjects with normal lipids and normal blood glucose (11 men and 11 pre-menopausal women). An oral unsaturated fat load test (OFLT: 50 g fat per m2 body surface) was performed using a commercial liquid preparation of long chai…

AdultMalemedicine.medical_specialty030209 endocrinology & metabolismmedicine.disease_cause03 medical and health scienceschemistry.chemical_compoundSex Factors0302 clinical medicineInternal medicinemedicineHumansPharmacology (medical)TriglyceridesFasting stateGeneral Environmental Science030219 obstetrics & reproductive medicineGlutathione Disulfidebusiness.industryUnsaturated fatHealthy subjectsGeneral EngineeringComplement C3FastingGlutathioneMiddle AgedPostprandial PeriodGlutathioneLipidsFats UnsaturatedOxidized GlutathioneOxidative StressEndocrinologychemistryGeneral Earth and Planetary SciencesFemaleCardiology and Cardiovascular MedicineNormal blood glucosebusinessLong chainBiomarkersOxidative stressClínica e Investigación en Arteriosclerosis (English Edition)
researchProduct

Surface electrical stimulation of the quadriceps femoris in patients affected by haemophilia A.

2006

Eighteen sessions of surface electrical stimulation was applied to the quadriceps femoris of the left leg of ten male subjects affected by severe haemophilia A, while ten healthy subjects constituted the control group. The isometric strength, the electromyographic activity and the diameter of the rectus femoris were measured in both legs before and after a six-week treatment period. After the treatment, the people affected by haemophilia showed a gain in strength by 13.8% in the stimulated leg and by 17.1% in the non-stimulated one. No changes were detected in the electromyographic activity. On the contrary, the diameter of the rectus femoris of the stimulated leg increased in 24.34%, while…

AdultMalemedicine.medical_specialtyAdolescentHaemophilia AStimulationElectric Stimulation TherapyIsometric exerciseHaemophiliaHemophilia AQuadriceps MusclePhysical medicine and rehabilitationIsometric ContractionmedicineHumansIn patientGenetics (clinical)business.industryHealthy subjectsHematologyGeneral MedicineMiddle Agedmedicine.diseaseTreatment periodAnesthesiaCase-Control StudiesSevere haemophilia AbusinessHaemophilia : the official journal of the World Federation of Hemophilia
researchProduct

Handling forces for the use of different inhaler devices.

2019

Abstract Age and comorbidities can impact on the success of handling an inhaler. In this pilot study, we assessed finger strength in 62 participants (aged 5–17 years [n = 20], 18–65 years [n = 22] and > 65 years [n = 20]) by using different types of inhalers with integrated sensors (Respimat®, Breezhaler®, Aerolizer®, Genuair®, Diskus®, Ellipta®, HandiHaler®, Turbohaler® and a pressurized metered-dose inhaler [Atrovent®]). Parameters under investigation included the spontaneous and maximum achievable force and torque required to operate devices. Satisfaction with individual inhalers, and the relationship between satisfaction and strength, were also assessed. There was a marked difference in…

AdultMalemedicine.medical_specialtyAdolescentPharmaceutical SciencePilot Projects02 engineering and technology030226 pharmacology & pharmacyFingers03 medical and health sciencesYoung Adult0302 clinical medicineAge groupsRheumatic DiseasesAdministration InhalationMedicineHumansChildAgedAged 80 and overHand Strengthbusiness.industryInhalerNebulizers and VaporizersHealthy subjectsAge FactorsRheumatic diseaseEquipment DesignMiddle Aged021001 nanoscience & nanotechnologyPatient preferenceDry-powder inhalerPatient SatisfactionCase-Control StudiesChild PreschoolPhysical therapyFemale0210 nano-technologybusinessInternational journal of pharmaceutics
researchProduct

Comparison of Peak Cough Flows Measured by Pneumotachograph and a Portable Peak Flow Meter

2004

To compare peak cough flows (PCF) obtained with a pneumotachograph (PCFp) with those measured using a portable peak flow meter (PCFm) in a population of healthy subjects and patients with neuromuscular disease.A total of 30 healthy subjects and 32 medically stable patients with neuromuscular diseases were studied. Using an oronasal mask connected, in a randomized order, to a pneumotachograph and to a portable peak flow meter, PCFp and PCFm were measured as every subject performed maximal cough efforts from total lung capacity.PCFp measurements were 377.70 +/-179.28 liters/min and PCFm measurements were 377.50 +/- 172.98 liters/min (not significant). The two measurements were correlated (r =…

AdultMalemedicine.medical_specialtyAdolescentPopulationPeak Expiratory Flow RatePhysical Therapy Sports Therapy and RehabilitationmedicineHumansLung volumeseducationAgededucation.field_of_studybusiness.industryRehabilitationHealthy subjectsNeuromuscular DiseasesMiddle AgedSurgeryClinical PracticePortable peak flow meterCoughFemaleFlowmetersNuclear medicinebusinessAmerican Journal of Physical Medicine & Rehabilitation
researchProduct

Influence of age and sex on aortic distensibility assessed by MRI in healthy subjects

2010

International audience; Abstract: Magnetic resonance imaging (MRI) is particularly well adapted to the evaluation of aortic distensibility. The calculation of this parameter, based on the change in vessel cross-sectional area per unit change in blood pressure, requires precise delineation of the aortic wall on a series of cine-MR images. Firstly, the study consisted in validating a new automatic method to assess aortic elasticity. Secondly, aortic distensibility was studied for the ascending and descending thoracic aortas in 26 healthy subjects. Two homogeneous groups were available to evaluate the influence of sex and age (with an age limit value of 35 years). The automatic postprocessing …

AdultMalemedicine.medical_specialtyAgingPopulationBiomedical EngineeringBiophysics030204 cardiovascular system & hematology030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicineSex FactorsAutomatic processingmedicine.arteryInternal medicineElastic ModulusAscending aortaImage Interpretation Computer-Assistedmedicine[INFO.INFO-IM]Computer Science [cs]/Medical ImagingHumansRadiology Nuclear Medicine and imagingHealthy subjectseducationAortaAortaeducation.field_of_studymedicine.diagnostic_test[ INFO.INFO-IM ] Computer Science [cs]/Medical Imagingbusiness.industryMagnetic resonance imagingMagnetic Resonance ImagingElasticityBlood pressureDescending aortaCirculatory systemCardiologycardiovascular systemElasticity Imaging TechniquesAortic stiffnessFemaleRadiologybusinessMRI
researchProduct

Corneal Thickness Response after Anesthetic Eye Drops: Our Own Results and Meta-Analysis.

2017

We aimed to test if there are different patterns in the central corneal thickness (CCT) response after instilling oxybuprocaine anesthetic eye drops and also to determine whether there is a significant change in the CCT. CCT was measured in 60 eyes of 60 healthy subjects before and during the hour after oxybuprocaine 0.4% eye drops were instilled. In addition, a systematic review and meta-analysis were carried out in order to answer the following PICO (patient, intervention, comparison, and outcome) question: What effect do anesthetic eye drops have on CCT values? We found no significant changes in the mean CCT values during the hour’s observation (ANOVA, p=0.209), and the meta-analysis rev…

AdultMalemedicine.medical_specialtyArticle Subjectgenetic structureslcsh:MedicineGeneral Biochemistry Genetics and Molecular BiologyCornea03 medical and health sciences0302 clinical medicineOphthalmologyMedicineHumans030212 general & internal medicineProspective StudiesOxybuprocaineAnesthetics LocalGeneral Immunology and Microbiologybusiness.industrylcsh:RHealthy subjectsGeneral Medicineeye diseasesHealthy VolunteersMeta-analysisAnesthetic030221 ophthalmology & optometryFemaleAnalysis of variancesense organsOphthalmic SolutionsbusinessProcainemedicine.drugResearch ArticleBioMed research international
researchProduct

Static posturography with dynamic tests. Usefulness of biomechanical parameters in assessing vestibular patients.

2012

Abstract Introduction and objective Posturography allows us in evaluating postural control. This study showed the posturographic parameters that were useful for assessing the functional ability to maintain balance in our sample of vestibular patients. Material and methods Of a total of 89 patients, 59 were healthy subjects and 30 had a peripheral vestibular disorder. The subjects were studied using the posturographic NedSVE/IBV system, combining static (Romberg) and dynamic (stability limits and rhythmic weight shifts) tests. We then compared the measurements found in the groups. Results Normal subjects showed significantly lower oscillations than our patients in all of the posturographic p…

AdultMalemedicine.medical_specialtyAudiologyPostural controlPhysical medicine and rehabilitationPeripheral vestibular disorderNystagmus PhysiologicCaloric TestsMedicineHumansFunctional abilityPostural BalanceBalance (ability)AgedVestibular systembusiness.industryPosturographyHealthy subjectsGeneral MedicineMiddle AgedVestibular Function TestsBiomechanical PhenomenaVestibular DiseasesWeight shiftAudiometry Pure-ToneFemalebusinessActa otorrinolaringologica espanola
researchProduct

An Eighteen-Minute Submaximal Exercise Test to Assess Cardiac Fitness in Response to Aerobic Training

2018

Romagnoli, M, Alis, R, Sanchis-Gomar, F, Lippi, G, and Arduini, A. An 18-minute submaximal exercise test to assess cardiac fitness in response to aerobic training. J Strength Cond Res 32(10): 2846-2852, 2018-We aimed to evaluate the utility of a submaximal heart rate recovery (HRR) test to monitor changes in cardiac fitness after aerobic training. Twenty healthy subjects were assigned to a control (n = 10) or a training (n = 10) group. Subjects in the training group performed 8 weeks of bicycle training, followed by 8 weeks of detraining. Heart rate recovery was assessed after exercises at 65% and 80% HRmax. The HRR test was performed at weeks 0 (W0), 4 (W4), 8 (W8), and 16 (W16) in the tra…

AdultMalemedicine.medical_specialtyCardiac FitnessPhysical Therapy Sports Therapy and RehabilitationSubmaximal exerciseRecovery periodHeart RateHeart ratemedicineHumansAerobic exerciseAerobic TrainingOrthopedics and Sports MedicineExercisebusiness.industryAMAXHealthy subjectsGeneral MedicineMiddle AgedTest (assessment)Highly sensitiveExercise Cardiac Fitness Aerobic TrainingCardiorespiratory FitnessExercise TestPhysical therapyFemalebusinesshuman activitiesPhysical Conditioning HumanJournal of Strength and Conditioning Research
researchProduct