Search results for "Heart"
showing 10 items of 3201 documents
Side effects and complications of intraosseous anesthesia and conventional oral anesthesia
2011
Objective: To analyze the side effects and complications following intraosseous anesthesia (IA), comparing them with those of the conventional oral anesthesia techniques. Material and method: A simple-blind, prospective clinical study was carried out. Each patient underwent two anesthetic techniques: conventional (local infiltration and locoregional anesthetic block) and intraosseous, for respective dental operations. In order to allow comparison of IA versus conventional anesthesia, the two operations were similar and affected the same two teeth in opposite quadrants. Heart rate was recorded in all cases before injection of the anesthetic solution and again 30 seconds after injection. The …
Rationale and design of dal-VESSEL: a study to assess the safety and efficacy of dalcetrapib on endothelial function using brachial artery flow-media…
2011
Dalcetrapib increases high-density lipoprotein cholesterol (HDL-C) levels through effects on cholesteryl ester transfer protein (CETP). As part of the dalcetrapib dal-HEART clinical trial programme, the efficacy and safety of dalcetrapib is assessed in coronary heart disease (CHD) patients in the dal-VESSEL study (ClinicalTrials.gov identifier: NCT00655538), the design and methods of which are presented here. RESEARCH DESIGN AND STUDY METHOD: Men and women with CHD or CHD risk equivalent, with HDL-C levels50 mg/dL were recruited for a 36-week, double-blinded, placebo-controlled trial. After a pre-randomisation phase of up to 8 weeks, patients received dalcetrapib 600 mg/day or placebo in …
A Comparative Study of Blood Lactate Tests in Swimming*
1989
Three different modes of lactate tests were studied. Eleven male competitive swimmers performed the tests (n.100 m, n.300 m, 2.100m + 2.400 m) within 5 days. Swimming velocity (V) vs blood lactate (BLa) and V vs heart rate (HR) curves were averaged. In V vs BLa comparisons, the BLa values of 4 mmol.l-1 in 2.400 m, 3 mmol.l-1 in n.300 m, and 2 mmol.l-1 in n.100 m modes were found to correspond to the same V. Although the resting BLa values were similar before the testing occasions, the initial BLa value in very easy swimming was lower in the n.300 m than in the n.100 m mode. The elimination of lactate most probably caused this difference. The highest BLa value was measured in the n.100 m (14…
Elevated concentration of oxidized LDL together with poor cardiorespiratory and abdominal muscle fitness predicts metabolic syndrome in young men
2013
Metabolic syndrome (MetS) is associated with increased oxidized LDL (ox-LDL), systemic inflammation, and poor cardiorespiratory fitness. We examined affiliations of these factors and the effect of muscular fitness on MetS in young healthy men.Physical fitness, ox-LDL, tumor necrosis factor α (TNFα), interleukin-6 (IL-6) and serum lipids were measured in a nationally representative sample of Finnish young men with and without MetS. Participants (mean age 25.1years) performed tests of maximal oxygen uptake (VO₂max) and muscle fitness, and were divided into MetS (n=54, IDF 2007 criteria) and non-MetS (n=790). Age, smoking and leisure-time physical activity were used as covariates (ANCOVA).The …
Rosiglitazone Causes Endothelial Dysfunction in Humans
2011
We explored the impact of rosiglitazone on endothelial function in normal volunteers and its interaction with glyceryl trinitrate (GTN)-induced abnormalities in endothelial function. We hypothesized that rosiglitazone would have a neutral effect on endothelial function in normal volunteers and would favorably modify endothelial dysfunction induced by GTN.In this double-blind, randomized, placebo-controlled study, 44 participants were randomized to placebo, rosiglitazone (4 mg twice daily), transdermal GTN (0.6 mg/h), or both GTN and rosiglitazone. After 7 days of treatment, participants underwent measures of forearm blood flow during brachial artery infusion of acetylcholine (Ach). Serum gl…
Cardiovascular effects of impulse noise, road traffic noise, and intermittent pink noise at LAeq = 75 dB, as a function of sex, age, and level of anx…
1992
In a previous paper, in which the experimental conditions of the present research are fully described (Parrot et al., this issue), heart rate (HR) was studied in 60 male and in 60 female subjects in response to a pile-driver noise (P), a gunfire noise (G), a road traffic noise (T), and an intermittent pink noise (R), all noises being emitted at the same LAeq = 75 dB for 15 min. Digital pulse level (PL) responses were concomitantly surveyed by the use of pulse oximetry, allowing continuous arterial oxygen saturation (SaO2) readings. An index of pulse reactivity (PRI) could be calculated. Arterial blood pressure was measured 7 times from the beginning to the end of each trial. At rest, within…
What happens when we get angry? Hormonal, cardiovascular and asymmetrical brain responses
2010
This study aimed to evaluate neuroendocrine and cardiovascular responses together with changes in brain asymmetry following an anger mood induction laboratory task. Previous research has shown an increase in heart rate and blood pressure when anger is experienced. Increased testosterone and decreased cortisol in response to anger and aggressive behavior have also been reported. With regard to asymmetrical frontal brain activity and emotion, the valence model links negative affect (as anger) to the right hemisphere while the motivational direction model links approach-related emotions (as anger) to the left hemisphere. From the subjective perception and from the neuroendocrine and cardiovasc…
Cardiovascular effects of impulse noise, road traffic noise, and intermittent pink noise at LAeq = 75 dB, as a function of sex, age, and level of anx…
1992
This study aimed at comparing for their cardiovascular effects: a pile-driver noise (P), a gunfire noise (G), a road traffic noise (T), an intermittent pink noise (R). All noises were presented at the same LAeq = 75 dB for 15 min each. Some 120 subjects were divided into 8 subgroups of 15 subjects each: OM (men between 40 and 50 years of age), OF (women, same age range), YM (men, between 15 and 20 years of age), YF (women, same age range), AM (typically anxious men, 20–25 years of age), AF (typically anxious women, same age range), NM (typicall anxiety-free men, same age range), and NF (typically anxiety-free women, same age range). Heart rate (HR), digital pulse level, and arterial blood p…
Concurrent validation of the OMNI-resistance exercise scale of perceived exertion with Thera-band resistance bands.
2012
The concurrent validity of the OMNI-Resistance Exercise Scale (OMNI-RES) of perceived exertion for use with elastic bands was studied during isotonic resistance exercises. Twenty healthy, physically active subjects completed both familiarization and testing sessions. The criterion variables were myoelectric activity, recorded by electromyography, and heart rate, recorded by a heart rate monitor. The subjects performed 2 separate sets of 15 repetitions in each of the 2 testing sessions and for each of the exercises applied (i.e., frontal and lateral raises). One set was carried out with the separation between the hands gripping the elastic band allowing that 15 repetition maximum to be perfo…
Reliability of different models to assess heart rate recovery after submaximal bicycle exercise.
2011
Abstract Objectives : Different models to assess HR recovery have been developed but knowledge of their reliability is poor at different submaximal exercise intensities and recovery durations. Our aim was to determine the reliability of HR recovery after a test on a cycle ergometer. Design : Twenty-one healthy individuals performed a submaximal exercise at 65% and 80% HR max followed by passive recovery. The exercise was repeated (retest) within 2 weeks to assess reliability. Method : HR recovery was assessed by 8 models, based on monoexponential kinetics or absolute recovery (recovered HR at fix time points). Intraclass correlation coefficient (ICC) and standard error of measurement (SEM, …