Search results for "Heterogeneity."
showing 10 items of 388 documents
Heterogeneous network games: Conflicting preferences
2013
Proceeding at: 2nd Annual UECE Lisbon Meeting: Game Theory and Applications, took place 2010, November, 4-6, in Lisbon (Portugal). The event Web site http://pascal.iseg.utl.pt/~uece/lisbonmeetings2010/ In many economic situations, a player pursues coordination or anti-coordination with her neighbors on a network, but she also has intrinsic preferences among the available options. We here introduce a model which allows to analyze this issue by means of a simple framework in which players endowed with an idiosyncratic identity interact on a social network through strategic complements or substitutes. We classify the possible types of Nash equilibria under complete information, finding two thr…
Modeling multiple taxis: Tumor invasion with phenotypic heterogeneity, haptotaxis, and unilateral interspecies repellence
2021
We provide a short review of existing models with multiple taxis performed by (at least) one species and consider a new mathematical model for tumor invasion featuring two mutually exclusive cell phenotypes (migrating and proliferating). The migrating cells perform nonlinear diffusion and two types of taxis in response to non-diffusing cues: away from proliferating cells and up the gradient of surrounding tissue. Transitions between the two cell subpopulations are influenced by subcellular (receptor binding) dynamics, thus conferring the setting a multiscale character. We prove global existence of weak solutions to a simplified model version and perform numerical simulations for the full se…
EXOSOMES DERIVED FROM METASTATIC COLON CANCER CELLS TRANSFER MALIGNANT PHENOTYPIC TRAITS TO SURROUNDING CELLS: THEIR EMERGING ROLE IN TUMOR HETEROGEN…
2018
Several studies have clearly demonstrated that within a heterogeneous tumor mass the inter-clonal cooperation between metastatic and non-metastatic cells can facilitate the tumor progression. Recent accumulating evidence has highlighted that tumor-derived exosomes (TDEs) play a relevant role as mediator of the inter-clonal collaborative cooperation affecting the properties of both tumor and non-tumor component. In this context, our goal was to understand if exosomes derived from highly metastatic cells may influence the behaviour of less aggressive tumor cells and the properties of endothelium. We found that metastatic SW620 cells transfer through exosomes (SW620Exos) their round/amoeboid p…
18F-FDG PET for breast cancer : combined analysis of tumour perfusion and metabolism for tumour characterisation and neoadjuvant chemotherapy respons…
2020
Neoadjuvant chemotherapy (NAC) is a common treatment in patients with locally advanced or large breast cancer at diagnosis. A pathological complete response (pCR) at the end of NAC is recognized as a good surrogate marker of relapse-free survival. An early identification of the pathological response has then become a key parameter to monitor new therapeutic strategies. Studies, focusing on predictive biomarkers identification, have shown that early changes in tumour metabolism, assessed by Positron Emission Tomography (PET) using 2-desoxy-2-18F-fluoro-D-glucose (18F-FDG), allow the early assessment of the pathological response at the end of treatment. However, given the diversity of breast …
Latent Class Approach to Estimate the Willingness to Pay for Transit User Information
2012
The aim of analysis is to understand how unreliable information influences user behaviour and how much it discourages public transport use. For this purpose, a Stated Preference Survey was carried out in order to know the preferences of public transport users relating to information needs and uncertainty on the information provided by Advanced Traveller Information System (ATIS). The perceived uncertainty is defined as information inaccuracy. In our study, we consider- ed the difference between forecasted or scheduled waiting time at the bus stop and/or metro station provided by ATIS, and that experienced by user, to catch the bus and/or metro. A questionnaire was submitted to an appropriat…
Determinants of Team Performance in Business Organizations
2013
Elektroniskā versija nesatur pielikumus
Kawasaki disease in Sicily: clinical description and markers of disease severity
2016
Background: Kawasaki disease (KD) is an acute systemic vasculitis of small and middle size arteries; 15-25 % of untreated patients and 5 % of patients treated with intravenous immunoglobulin (IVIG) develop coronary artery lesions (CAL). Many studies tried to find the most effective treatment in the management of resistant KD and to select the risk factors for CAL. Our data are assessed on children from west Sicily, characterized by a genetic heterogeneity. Methods: We studied the clinical data of 70 KD Sicilian children (36 males: 51 %; 34 females: 49 %), analysed retrospectively, including: demographic and laboratory parameters; echocardiographic findings at diagnosis, at 2, 6 and 8 weeks,…
A heterogeneous and reconfigurable machine-vision system
1995
This paper describes a new machine-vision system, a HERMIA heterogeneous and reconfigurable machine for image analysis. The architecture topology of the HERMIA machine is reconfigurable; moreover, the integration of its special modules allows a search for optimal strategies to solve vision problems. The general architecture and the hardware implementation are described. The software environment of the HERMIA machine provides a full iconic interface and a pictorial language oriented to vision in multiprocessor architectures. The preliminary system evaluation and applications are shown. © 1995 Springer-Verlag.
Interpreting Heterogeneous Geospatial Data Using Semantic Web Technologies
2016
International audience; The paper presents work on implementation of semantic technologies within a geospatial environment to provide a common base for further semantic interpretation. The work adds on the current works in similar areas where priorities are more on spatial data integration. We assert that having a common unified semantic view on heterogeneous datasets provides a dimension that allows us to extend beyond conventional concepts of searchability, reusability, composability and interoperability of digital geospatial data. It provides contextual understanding on geodata that will enhance effective interpretations through possible reasoning capabilities. We highlight this through …
A Federated Approach for Interoperating AEC/FM Ontologies
2016
International audience; Over the last few years, the benefits of applying ontologies (semantic graph modelling) for Architecture, Engineering, Construction and Facility Management (AEC/FM) industry have been recognized by several researchers and industry stakeholders. One of the main motivations is because it eases AEC data manipulation and representation. However, a research question that still remains open is how to take advantage of semantic web technologies to interoperate the AEC/FM and other ontologies in a flexible and dynamical way in order to solve data structure heterogeneity problem. Because of this, we propose in this paper to apply a rule-based federated architecture to answer …