Search results for "Hf"
showing 10 items of 909 documents
The Influence of Entrepreneurial Learning in New Firms’ Performance: A Study in Costa Rica
2014
The creation of new firms is important for the economy, and entrepreneurial learning is essential for the performance of new firms. We contribute to existing knowledge by combining these two topics and considering a third one: The role of multinational companies (MNCs) as a source of learning for the entrepreneur. This approach has rarely been taken in the literature. We investigated the performance of a group of young companies created by former employees of MNCs and their relationship with entrepreneurial learning in such companies. The study was based on a sample of 175 former employees of MNCs in Costa Rica, who founded their own firm between 2001 and 2007. The control group was formed …
La actitud del vendedor ante las innovaciones tecnológicas y su influencia en su desempeño en las ventas
2017
El objetivo de este trabajo es determinar cómo la actitud que tienen los vendedores ante la tecnología puede representar un factor decisivo en la implementación de los procesos de automatización de la fuerza de ventas (AFV). Se parte del modelo de aceptación tecnológica (tam, por su sigla en inglés), que asume que la actitud viene determinada por la utilidad percibida y por la facilidad de uso de esta, e introducimos como novedad en el modelo su relación con el desempeño. Se contrasta el modelo conceptual en una muestra de vendedores colombianos a través de un modelo de ecuaciones estructurales. Los resultados establecen que la percepción de la facilidad de uso de la tecnología influye posi…
Impact evaluation of EU funds: Examples in infrastructure projects
2011
Being one of investment areas within EU Cohesion policy the sector of public infrastructure frequently faces the issue of efficiency. This issue largely arises from the lack of theoretical and practical concepts on how the evaluation techniques could achieve rigorous estimations of the investment impact on the current processes in the sector. The present paper seeks to contribute to these discussions by defining crucial problems in developing rigorous estimations relevant to public infrastructure projects and setting the assumptions. The research method is comparative and logical analysis of the theoretical concepts, methods and conclusions, published in scientific literature including poli…
Effectiveness and safety of a new helmet CPAP configuration allowing tidal volume monitoring in patients with COVID-19.
2021
Abstract Background High generated tidal volumes (Vt) have been correlated with higher risk of self-induced lung injury and worse clinical outcome. This study aimed to evaluate the effectiveness and safety of a new helmet continuous positive airway pressure delivered (h-CPAP) configuration allowing Vt monitoring in patients affected by COVID-19. Methods This prospective observational study was performed in the respiratory intermediate care unit of University Hospital in Turin, Italy, between March 24th, and June 15th, 2020. Included patients were treated with CPAP via a single-limb intentional leak configuration by a turbine-driven ventilator, provided with a dedicated patch. Effectiveness …
Early pronation, protective lung ventilation and use of awake-prone-HFNO therapy after extubation in near-fatal drowning
2023
the lack of comparative studies and of multicenter trials still makes the treatment of the lung injured drowned patient a challenge for intensivists. Although the outcome of drowned patients is related to the potential neurological sequalae, AHRF remains the main concern. Ventilation guidelines for drowning patients are mainly adapted from AHRF patients and may not reflect the needs of this particular population. Our result confirms that early pronation, in cases of lack of improvement of oxygenation, might be the correct strategy.14 In addition, HFNO and awake prone position might have a role in avoiding reintubation while maintaining adequate pulmonary gas exchanges.
Timing of Renal Replacement Therapy for Severe Acute Kidney Injury in Critically Ill Patients
2019
Acute kidney injury (AKI) affects many ICU patients and is responsible for increased morbidity and mortality. Although lifesaving in many situations, renal replacement therapy (RRT) may be associated with complications, and the appropriate timing of its initiation is still the subject of intense debate. An early initiation strategy can prevent some metabolic complications, whereas a delayed one may allow for renal function recovery in some patients without need for this costly and potentially dangerous technique. For years, most of the knowledge on this issue stemmed from observational studies or small randomized controlled trials. Recent randomized controlled trials have indicated that a w…
Systemic Thrombolytic Therapy for Acute Pulmonary Embolism: Who Is a Candidate?
2017
Pulmonary embolism (PE) is a major cause of both acute and long-term morbidity for a large number of patients worldwide, and massive PE is frequently fatal. Right ventricular (RV) dysfunction is a key determinant of prognosis in the acute phase of PE. Patients with clinically overt RV failure, that is, with cardiogenic shock or persistent hypotension at presentation (acute high-risk PE), are clearly in need of immediate reperfusion treatment with systemic thrombolysis or, alternatively, surgical or catheter-directed techniques. On the other hand, within the large group of patients presenting without hemodynamic instability, the bleeding risk of full-dose intravenous thrombolytic treatment h…
Synthesis and electronic aspects of tetrahydrobenzothienopyrimidine derivatives
2015
Abstract The chemistry of thiophenes, pyrimidines, triazolopyrimidines and benzothiophenes has drawn much attention because of their biological activities. Their interesting properties are connected with their complex π-electron delocalisation effects. Herein the synthesis, crystal and molecular structures at 100 K and DFT calculated structures of three tetrahydrobenzothienopyrimidine derivatives are reported i.e. 4-hydrazino-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidine which was a substrate for 2-phenyl-8,9,10,11-tetrahydro[1]benzothieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine and 3-methyl-9,10,11,12-tetrahydro-2H-[1]benzothieno[2′,3′:4,5]pyrimido[1,6-b][1,2,4]triazin-2-one. Moreover t…