Search results for "High-density"

showing 10 items of 139 documents

Effect of rat plasma high density lipoprotein with or without apolipoprotein E on the cholesterol uptake and on the induction of the corticosteroid b…

1991

Abstract High density lipoprotein (HDL) has been shown to induce the cellular accumulation of cholesterol esters and the biosynthesis of 21-hydroxysteroids (corticosteroids) newborn rat adrenocortical cells cultivated in serum-free medium. In order to identify the component(s) of HDL responsible for these effects, we investigated the ability of rat HDL subfractions and HDL with or without apolipoprotein E to deliver cholesterol to cells and to stimulate the steroid biosynthetic pathways in adrenal cultured cells. The total cholesterol uptake from HDL 2 was greater than that observed with HDL rich in apolipoprotein E (HDL 1 and HDL c ). Furthermore, the increase of the ratio between 21-hydro…

Apolipoprotein Emedicine.medical_specialtyApolipoprotein Bmedicine.medical_treatmentBiologySteroidMicechemistry.chemical_compoundApolipoproteins EHigh-density lipoproteinBiosynthesisAdrenal Cortex HormonesCorticosteroneInternal medicinemedicineAnimalsMolecular BiologyCells CulturedCholesterolnutritional and metabolic diseasesCell BiologyRatsLipoproteins LDLCholesterolEndocrinologyAnimals NewbornchemistryAdrenal Cortexbiology.proteinlipids (amino acids peptides and proteins)Apolipoprotein C2Lipoproteins HDLBiochimica et Biophysica Acta (BBA) - Molecular Cell Research
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Effects of dietary fiber intake on risk factors for cardiovascular disease in subjects at high risk

2009

Background: Epidemiological studies and feeding trials with supplements suggest that fibre intake is associated with a reduction in cardiovascular risk. However, the effects of changes in dietary fibre on risk factor levels have not been evaluated in free-living individuals. Thus, the effects of changes in dietary fibre intake on cardiovascular risk factors were assessed over 3 months in free-living high-risk subjects. Methods: 772 high-risk subjects (age 69±5 years) were assigned to a low-fat diet or two Mediterranean-style diets. All participants received behavioural and nutritional education, including recommendations for increasing the consumption of vegetables, fruits, and legumes. Cha…

Blood GlucoseMale030309 nutrition & dieteticsEpidemiologyBlood lipidsPhysiology030204 cardiovascular system & hematologyDiet Mediterraneanchemistry.chemical_compound0302 clinical medicineHigh-density lipoproteinUNESCO::CIENCIAS MÉDICAS ::Salud públicaDiet Fat-Restricted2. Zero hunger0303 health sciencesEvidence-Based MedicineMiddle Aged:CIENCIAS MÉDICAS [UNESCO]Cardiovascular diseaseDietary fiberHigh risk subjects3. Good healthC-Reactive ProteinCardiovascular diseasesCholesterolEstudi de casosCardiovascular DiseasesUNESCO::CIENCIAS MÉDICASCohortCytokinesFemalemedicine.medical_specialtyWaistDiet therapyC-reactive proteinARTHEROSCLEROSIS03 medical and health sciencesInternal medicinemedicineFibra alimentàriaHumans:CIENCIAS MÉDICAS ::Salud pública [UNESCO]Blood glucoseDietary fiber ; Risk factors ; Cardiovascular disease ; High risk subjectsRisk factorEpidemiologiaAgedNutritionCholesterolbusiness.industryMalalties cardiovascularsCholesterol HDLPublic Health Environmental and Occupational HealthCholesterol LDLAtherosclerosisBlood pressureEndocrinologychemistryRisk factorsCase studiessense organsbusinessEnergy Intake
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Effects of oral niacin on endothelial dysfunction in patients with coronary artery disease: Results of the randomized, double-blind, placebo-controll…

2009

High-density-lipoproteins-cholesterol (HDL-C) is invertedly related to the incidence of cardiovascular events. Recent studies suggest that HDL-C directly improves endothelial function. Nicotinic acid (niacin) effectively raises serum HDL-C. We therefore hypothesized that treatment with niacin improves endothelial dysfunction in patients with coronary artery disease (CAD). One hundred seven patients with CAD were randomly assigned to double-blinded treatment for 12 weeks with extended-release (ER)-niacin 1000 mg/day (N) or placebo (C), respectively. Flow-mediated dilation (FMD) of the brachial artery, nitroglycerin-mediated endothelium-independent dilation (NMD) and serum lipid concentration…

Blood GlucoseMalemedicine.medical_specialtyBrachial ArteryVasodilator AgentsAdministration OralCoronary Artery DiseasePlaceboNiacinGastroenterologyCoronary artery diseaseNitroglycerinchemistry.chemical_compoundHigh-density lipoproteinDouble-Blind MethodInternal medicinemedicine.arterymedicineHumansProspective StudiesPhosphorylationEndothelial dysfunctionBrachial arteryTriglyceridesAgedUltrasonographyVascular diseasebusiness.industryCholesterol HDLMicrofilament Proteinsnutritional and metabolic diseasesCholesterol LDLMiddle AgedPhosphoproteinsmedicine.diseaseVasodilationB vitaminsTreatment OutcomeEndocrinologychemistryDelayed-Action PreparationsFemalelipids (amino acids peptides and proteins)Endothelium VascularCardiology and Cardiovascular MedicinebusinessCell Adhesion MoleculesBiomarkersNiacinAtherosclerosis
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Associations Between Built Environment Characteristics and Walking in Older Adults in a High-Density City: A Study From a Chinese Megacity

2020

The built environment is an important factor affecting physical activity, especially walkability. Walkability is used to characterize the user friendliness of outdoor physical activity. However, studies on walkability and physical activity are mainly concentrated on low-density Western cities. Study on the walkability of high-density cities in Asia, especially with the elderly, is seriously lacking. And walkability is often used as a composite indicator. This study mainly re-examines the relationship between the common indicators of walkability (population density, street connectivity, land-use mix, and retail density), transport-related walking, and leisure-time walking with older adults i…

ChinaAsiaPhysical activityUser friendlinesswalking03 medical and health sciences0302 clinical medicineResidence CharacteristicsEnvironmental healthHumansElderly peopleleisure-time walking030212 general & internal medicineBuilt EnvironmentCitiesolder adultsBuilt environmentAgedOriginal Researchwalkabilitylcsh:Public aspects of medicine030503 health policy & servicesPublic Health Environmental and Occupational Healthlcsh:RA1-1270Middle AgedComposite indicatorhigh-density citytransport-related walkingMegacityGeographyWalkabilityEnvironment DesignPublic Health0305 other medical sciencehuman activitiesStatistical correlationFrontiers in Public Health
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Identification of off-flavor compounds in high-density polyethylene (HDPE) with different amounts of abscents

1998

The use of synthetic pipes for drinking water distribution has increased. High desnity polyethylene (HPDE) is preferred because of its favorable mechanical properties, ease of handling during manufacturing, and low permeability to external contaminants. Off-flavor drinking water is a problem with plastic pipes. The compounds causing off-flavors are mainly carbonyl compounds. A combined zeolite called Abscents is used to eliminate odors and to remove odor-causing compounds. In this study, four different amounts of Abscents were added to raw HDPE pellets, and the influence on the off-flavor properties were analyzed. When the maximum amount of Abscents was added, almost all the carbonyl compou…

ChromatographyPolymers and PlasticsPelletsConcentration effectGeneral ChemistryPolyethylenechemistry.chemical_compoundchemistryOdorMaterials ChemistryHigh-density polyethyleneGas chromatographyZeoliteFlavorPolymer Engineering & Science
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A comprehensive experimental study of the rheological behaviour of HDPE.

1986

Extensional properties of four high density polyethylenes with different molecular weights and molecular weight distributions are presented. The samples have already been well characterized in shear and non-isothermal extensional flow. The data were collected at 180 °C for elongational rates between 3 · 10−1 and 10−4s−1. Some qualitative and quantitative generalizations of the results are given.

End effectMaterials scienceShear (geology)RheologyShear viscosityPolymer chemistryHigh densityGeneral Materials ScienceDie swellHigh-density polyethyleneComposite materialCondensed Matter PhysicsExtensional definitionRheologica Acta
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Leisure time physical activity is associated with improved HDL functionality in high cardiovascular risk individuals: a cohort study.

2020

Abstract Aims Physical activity has consistently been shown to improve cardiovascular health and high-density lipoprotein-cholesterol levels. However, only small and heterogeneous studies have investigated the effect of exercise on high-density lipoprotein functions. Our aim is to evaluate, in the largest observational study to date, the association between leisure time physical activity and a range of high-density lipoprotein functional traits. Methods The study sample consisted of 296 Spanish adults at high cardiovascular risk. Usual leisure time physical activity and eight measures of high-density lipoprotein functionality were averaged over two measurements, one year apart. Multivariabl…

EpidemiologyEventsLeisure timephysical activity030204 cardiovascular system & hematologyCohort Studieschemistry.chemical_compound0302 clinical medicineRisk FactorsValidationHigh-density-lipoproteinAmpk0303 health sciencesbiologyCholesterolCardiovascular Diseaseslipids (amino acids peptides and proteins)Cardiology and Cardiovascular MedicineCohort studyAdultlifestyleActivity questionnairemedicine.medical_specialtyHDL functionCardiovascular healthPhysical activity03 medical and health sciencesLeisure ActivitiesInternal medicineCholesterylester transfer proteinmedicineHumansHdl functionalityExercise030304 developmental biologyCholesterolbusiness.industryPhysical activityProteinCholesterol HDLbiomarkersLifestyleHeart-diseaseCholesterol Ester Transfer ProteinschemistryDiabetes Mellitus Type 2Heart Disease Risk Factorsbiology.proteinbusinessBiomarkersEuropean journal of preventive cardiology
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A Genome-Wide Detection of Copy Number Variations Using SNP Genotyping Arrays in Braque Français Type Pyrénées Dogs

2019

Simple Summary Copy number variations (CNVs) are important sources of variation in mammalian species. In this study, we used a single nucleotide polymorphisms (SNP) array to detect CNVs in Braque Français, type Pyrénées dogs (BRA). Results overlapped moderately in comparison with previous studies on CNVs in dogs, leading to the identification of 16 novel CNVRs. Several genes were annotated in the CNV regions (CNVRs) detected, some of which related to muscle structure development. This breed is known to be excellent upland game birds dogs. The selection for such hunting behavior could have driven the presence of these genes into the CNVRs. Copy number variations may be of interest to study a…

False discovery rateSingle-nucleotide polymorphismComputational biologyBiologyGenomeSettore AGR/17 - Zootecnica Generale E Miglioramento Genetico03 medical and health sciencesBraque Français type Pyrénées dogcopy number variation (CNV) canine high-density SNP array; Braque Français type Pyrénées dogsGenetic variationlcsh:Zoologycanine high-density SNP arrayCopy-number variationlcsh:QL1-991030304 developmental biology0303 health scienceslcsh:Veterinary medicineGeneral VeterinaryMuscle cell differentiationCommunication030302 biochemistry & molecular biologycanine high-density SNP array; Braque Français type Pyrénées dogsSNP genotypingcopy number variation (CNV) canine high-density SNP arraycopy number variation (CNV)Veterinary (all)lcsh:SF600-1100Animal Science and ZoologyBraque Français type Pyrénées dogsSNP arrayAnimals
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Using organoclay to promote morphology refinement and co-continuity in high-density polyethylene/polyamide 6 blends – Effect of filler content and po…

2010

We investigate the gradual changes of the microstructure of two blends of high-density polyethylene (HOPE) and polyamide 6 (PA6) at opposite composition filled with increasing amounts of an organo-modified clay. The filler locates preferentially inside the polyamide phase, bringing about radical alterations in the micron-scale arrangement of the polymer phases. When the host polyamide represents the major constituent, a sudden reduction of the average sizes of the polyethylene droplets was observed upon addition of even low amounts of organoclay. A morphology refinement was also noticed at low filler contents when the particles distributes inside the minor phase. In this case, however, keep…

Filler (packaging)NanocompositeMaterials scienceNanocompositeImmiscible blendPolymers and PlasticsImmiscible blendsOrganic ChemistryPolyethylenechemistry.chemical_compoundNanocomposite; Immiscible blends; MicrostructurechemistryPhase (matter)PolyamideMaterials ChemistryOrganoclayHigh-density polyethylenePolymer blendComposite materialNanocomposite Immiscible blends MicrostructureMicrostructure
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Effects of persistent physical activity and inactivity on coronary risk factors in children and young adults. The Cardiovascular Risk in Young Finns …

1994

The tracking of physical activity and its influence on selected coronary heart disease risk factors were studied in a 6-year (original survey in 1980, with follow-ups in 1983 and 1986) study of Finnish adolescents and young adults as part of the Cardiovascular Risk in Young Finns Study. The subjects in this analysis were aged 12, 15, and 18 years at baseline. Physical activity was assessed with a standardized questionnaire, and a sum index was derived from the product of intensity, frequency, and duration of leisure time physical activity. Complete data on physical activity index from each study year were available on 961 participants. Significant tracking of physical activity was observed …

GerontologyMaleAdolescentEpidemiologyCross-sectional studymedicine.medical_treatmentPhysiologyPhysical exercise03 medical and health scienceschemistry.chemical_compound0302 clinical medicineHigh-density lipoproteinRisk FactorsMedicineHumansInsulin030212 general & internal medicineObesityYoung adultRisk factorChildExerciseFinlandTriglyceridebusiness.industryInsulinSmoking030229 sport sciencesmedicine.diseaseObesityLipidsDietCross-Sectional StudieschemistryCardiovascular DiseasesRegression AnalysisFemalebusinessFollow-Up StudiesAmerican journal of epidemiology
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