Search results for "Hindrances"
showing 5 items of 5 documents
Design of enzyme-mediated controlled release systems based on silica mesoporous supports capped with ester-glycol groups
2012
[EN] An ethylene glycol-capped hybrid material for the controlled release of molecules in the presence of esterase enzyme has been prepared. The final organic-inorganic hybrid solid S1 was synthesized by a two-step procedure. In the first step, the pores of an inorganic MCM-41 support (in the form of nanoparticles) were loaded with [Ru(bipy) 3]Cl 2 complex, and then, in the second step, the pore outlets were functionalized with ester glycol moieties that acted as molecular caps. In the absence of an enzyme, release of the complex from aqueous suspensions of S1 at pH 8.0 is inhibited due to the steric hindrance imposed by the bulky ester glycol moieties. Upon addition of esterase enzyme, del…
Ergonomics Awareness and Employee Performance: An Exploratory Study
2017
The study examined the effects of ergonomics on employee performance by ascertaining the level of ergonomics awareness in Nigerian organizations, identifying the factors hindering the use of ergonomic, and the best practices and methods adopted by various organizations across industries. Despite a knowledge of importance to a growing number of researchers in Nigeria, there is still a dearth in knowledge of ergonomics design and its implementation in Nigeria. This can be observed in the low level of its adoption. The study adopted an exploratory approach through the review of literature. It was seen that several factors have hindered the efficient implementation of ergonomics in Nigeria whic…
Modeling of the role of conformational dynamics in kinetics of the antigen-antibody interaction in heterogeneous phase.
2012
[EN] A novel approach that may potentially be used to study biomolecular interactions including the simultaneous determination of structural and kinetic binding parameters is described in this Article for the first time. It allows a rigid distinction between the possible reaction mechanisms of biomolecular recognition, induced fit and conformational selection. The relative importance of the two pathways is determined not by comparing rate constants but the structural aspects of the interaction instead. So the exact location of antigen molecules with respect to the capture antibody is depicted experimentally, avoiding the use of X-ray crystallography. The proposed pattern is applied to study…
Exploring the relationships between high involvement work system practices, work demands and emotional exhaustion: a multi-level study.
2016
This study explores the impact of enacted high involvement work systems (HIWS) practices on employee emotional exhaustion. This study hypothesized that work overload and job responsibility mediate the relationship between HIWS practices (ability, motivation, opportunity and work design HIWS practices) and employee emotional exhaustion. A total of 360 employees (nested within 49 work units) rated their feelings of work overload, job responsibility and emotional exhaustion. The line managers from these work units rated the enacted HIWS practices. Results indicate that ability- and motivation HIWS practices are positively related to work overload, and ability-, motivation- and work design HIWS…
Contact formation in random networks of elongated objects
2014
The effect of steric hindrance is an important aspect of granular packings as it gives rise to, e.g., limitations on the densities of ordered and disordered packings, both of which are essentially defined by the geometry of the constituents. Here we focus on random packing of rods via deposition and their distributions of contact number and segment length. Such statistical properties are relevant for mechanical properties of the structures, but the (quite large) steric effects on them have not been addressed in previous studies. We therefore develop a theory that describes the statistical properties of rod packings, while taking into account that the deposited rods cannot overlap and thus i…