Search results for "Hip"

BENEFICIOS RELACIONALES, SATISFACCIÓN Y LEALTAD EN EL COMERCIO MINORISTA: UNA COMPARATIVA INTERSECTORIAL

2009

RESUMENEn el contexto del marketing de relaciones, resulta de gran importancia para el establecimiento minorista identificar el tipo de beneficios de la relación que influye en mayor medida sobre sus resultados en términos de satisfacción del cliente y lealtad hacia el minorista, de manera que se garantice una relación continua y satisfactoria. Dichos beneficios pueden tener distinto peso en función del tipo de actividad llevada a cabo por el minorista. El presente trabajo pretende analizar empíricamente un modelo que refleje los distintos tipos de beneficios relacionales obtenidos por los clientes, así como los beneficios obtenidos por la organización en términos de lealtad del consumidor …

The politics of citizenship tests : time, integration and the contingent polity

2011

Delivery of proteins into living cells by reversible membrane permeabilization with streptolysin-O

2001

The pore-forming toxin streptolysin O (SLO) can be used to reversibly permeabilize adherent and nonadherent cells, allowing delivery of molecules with up to 100 kDa mass to the cytosol. Using FITC-labeled albumin, 10 5 –10 6 molecules were estimated to be entrapped per cell. Repair of toxin lesions depended on Ca 2+ -calmodulin and on intact microtubules, but was not sensitive to actin disruption or to inhibition of protein synthesis. Resealed cells were viable for days and retained the capacity to endocytose and to proliferate. The active domains of large clostridial toxins were introduced into three different cell lines. The domains were derived from Clostridium difficile B-toxin and Clo…

Metabotropic glutamate receptors activate phospholipase D in astrocytes through a protein kinase C-dependent and Rho-independent pathway.

2003

Metabotropic glutamate receptors (mGluRs) are G protein-coupled receptors that mediate phospholipase D (PLD) activation in brain, but the mechanism underlying this response remains unclear. Here we used primary cultures of astrocytes as a cell model to explore the mechanism that links mGluRs to PLD. Glutamate activated both phospholipase C (PLC) and PLD with equal potency and this effect was mimicked by L-cysteinesulfinic acid, a putative neurotransmitter previously shown to activate mGluRs coupled to PLD, but not PLC, in adult brain. PLD activation by glutamate was dependent on Ca(2+) mobilization and fully blocked by both protein kinase C (PKC) inhibitors and PKC down-regulation, suggesti…

Chronic ethanol exposure alters the levels, assembly, and cellular organization of the actin cytoskeleton and microtubules in hippocampal neurons in …

2010

The organization and dynamics of microtubules (MTs) and the actin cytoskeleton are critical for the correct development and functions of neurons, including intracellular traffic and signaling. In vitro ethanol exposure impairs endocytosis, exocytosis, and nucleocytoplasmic traffic in astrocytes and alters endocytosis in cultured neurons. In astrocytes, these effects relate to changes in the organization and/or function of MTs and the actin cytoskeleton. To evaluate this possibility in hippocampal cultured neurons, we analyzed if chronic ethanol exposure affects the levels, assembly, and cellular organization of both cytoskeleton elements and the possible underlying mechanisms of these effec…

Family Well-Being Under Pressure: Rhythmanalysis Applied to Post Pandemic Family Dynamics

2022

This contribution deals with the centrality of family relationships for the production of individual well-being, both on a cognitive level, i.e. as an influence on satisfaction with one’s own life and, therefore, as the outcome of a cognitive evaluation, and on an experiential and emotional level, i.e. as an influence on moment-to-moment experience. It starts from an analysis of subjective well-being, arriving at a concept of relational well-being, whilst proposing an approach of rhythmanalysis as a tool for understanding the changes occurring in family dynamics in the post-Covid era.

Access to European Institutions

2022

In this publication, I talk about the right of access to European institutions

L’amicizia politica nell’Ottocento: Giuseppe Mazzini e Francesco Crispi

2014

Giuseppe Mazzini and Francesco Crispi were very close friends. Their relationship is a typical case of political friendship in the nineteenth century. The first one was the political teacher and the living icon of Italian republicans. After the Unity, Crispi decided to leave republican side and to support constitutional parliament, even if under monarchy, unlike Mazzini, who wished conspire against the reign. This astonishing choice divided him from his old teacher Mazzini, and this loud breach between two great friends and democrat leaders broke the Left too.

Un dieu peut-il mourir ? Enquête sur la fin des cultes dans l’Antiquité gréco-romainedirigé par Karin Mackowiak et Christian Stein

2018

Bartomeu de Tresbens, physician and astrologer in the service of king Peter the Ceremonious and the infant John: between the service to the Crown and…

2018

Bartomeu de Tresbens was a physician, astrologer and philosopher at the service of two kings of the Crown of Aragon, Peter IV the Ceremonious and his son, Duke John, the future John I the Hunter, between 1360 and 1375, approximately. His major work of astrological content has hardly been studied, except for the Llibre de les nativitats (Book of Nativities). Similarly, most of his biography is not known. The documents, which are mainly the correspondence of its relationship with the monarchy, are preserved, but also other records that connect him to the municipalities of Barcelona and Cervera. Particularly in the latter case, Tresbens was tempted by the municipal authorities for being the ph…