Search results for "Histatin"

showing 3 items of 3 documents

Human infant saliva peptidome is modified with age and diet transition.

2012

Abstract In order to describe developmental changes in human salivary peptidome, whole saliva was obtained from 98 infants followed longitudinally at 3 and 6 months of age. Data on teeth eruption and diet at the age of 6 months were also recorded. Salivary peptide extracts were characterised by label-free MALDI-MS. Peptides differentially expressed between the two ages, and those significantly affected by teeth eruption or introduction of solid foods were identified by MALDI TOF–TOF and LC ESI MS–MS. Out of 81 peaks retained for statistical analysis, 26 were overexpressed at the age of 6 months. Exposure to solid foods had a more pronounced effect on profiles (overexpression of nine peaks) …

AdultMalemedicine.medical_specialtySalivaAgingProteomeBiophysicsBiology01 natural sciencesBiochemistryTooth Eruption03 medical and health sciencesstomatognathic systemInternal medicinemedicineHumansStatistical analysisWhole salivaSalivary Proteins and PeptidesSalivaComputingMilieux_MISCELLANEOUS030304 developmental biology0303 health sciencesChromatographyTransition (genetics)010401 analytical chemistryInfantFeeding Behavior0104 chemical sciencesEndocrinologySolid foodHistatinSalivary ProteinsFemalePeptides[SDV.AEN]Life Sciences [q-bio]/Food and NutritionJournal of proteomics
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Salivary and gingival crevicular fluid histatin in periodontal health and disease

2013

Objectives: Histatin, with its anti bacterial, anti protease, and wound closure stimulating property might influence the pathogenesis of periodontal disease. This study assessed the presence of histatin in gingival crevicular fluid (GCF); the levels of salivary and GCF histatin in periodontal disease. Material and methods: It was a cross sectional study that included systemically healthy forty five subjects (22 males and 23 females) between the age group of 20 to 45 years. Based on Gingival Index (Loe and Silness ,1963) and Russell’s Periodontal Index they were grouped as 15 healthy (Group 1), 15 gingivitis (Group 2), and 15 periodontitis (Group 3) subjects. Whole pooled unstimulated saliva…

PeriodontitisSalivabusiness.industryResearchSignificant differenceDentistryOdontologíaDiseasemedicine.disease:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludCrevicular fluidGingivitisstomatognathic systemHistatinUNESCO::CIENCIAS MÉDICASMedicinePeriodontologymedicine.symptomAnti bacterialbusinessGeneral Dentistry
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Conformation and concerted dynamics of the integrin-binding site and the C-terminal region of echistatin revealed by homonuclear NMR

2005

Copyright © by Portland Press. The final version of record is available at http://www.biochemj.org/bj/default.htm

Protein ConformationStereochemistryIntegrinNMR protein dynamics determinationTripeptideBiochemistryHomonuclear moleculeOff-resonance rotating-frame Overhauser enhancement spectroscopy (off-resonance ROESY)Protein structureSide chainAnimalsNuclear Magnetic Resonance BiomolecularMolecular BiologyIntegrin bindingRGD motifchemistry.chemical_classificationBinding Sites:CIENCIAS DE LA VIDA::Bioquímica [UNESCO]ChemistryEchistatin integrinSnakesUNESCO::CIENCIAS DE LA VIDA::BioquímicaCell BiologyRGD disintegrin; Echistatin; Integrin; NMR protein dynamics determination; Off-resonance rotating-frame Overhauser enhancement spectroscopy (off-resonance ROESY)Protein Structure TertiaryAmino acidRGD disintegrinDocking (molecular)EchistatinIntercellular Signaling Peptides and ProteinsPeptidesResearch ArticleProtein Binding
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