Search results for "Histology"

Protocolo de diagnóstico histológico para muestras de pacientes con melanoma cutáneo. Documento de consenso de la SEAP y la AEDV para el Registro Nac…

2020

Resumen: El presente texto es una propuesta de protocolo de diagnóstico histológico para el melanoma cutáneo realizada a instancias del Registro Nacional de Melanoma de la Academia Española de Dermatología y Venereología. Tras una búsqueda bibliográfica, un grupo de ocho panelistas (siete patólogos) decidieron entre 36 variables del tumor primario, el ganglio centinela y la linfadenectomía incluir un total de 30 variables mediante el método de Delphi modificado. Se han consensuado las variables que deberían contener un informe histológico de melanoma cutáneo para que puedan ser utilizadas en el Registro de Melanoma o servir de modelo para los distintos Servicios de Anatomía Patológica a la …

Protocolo de diagnóstico histológico para muestras de pacientes con melanoma cutáneo. Documento de consenso de la SEAP y la AEDV para el Registro Nac…

2021

This article describes a proposed protocol for the histologic diagnosis of cutaneous melanoma developed for the National Cutaneous Melanoma Registry managed by the Spanish Academy of Dermatology and Venereology (AEDV). Following a review of the literature, 36 variables relating to primary tumors, sentinel lymph nodes, and lymph node dissection were evaluated using the modified Delphi method by a panel of 8 specialists (including 7 pathologists). Consensus was reached on the 30 variables that should be included in all pathology reports for cutaneous melanoma and submitted to the Melanoma Registry. This list can also serve as a model to guide routine reporting in pathology departments.

Iris Claw Phakic Lens—Intermediate and Long-term Corneal Endothelial Changes

1994

OBJECTIVE: To study the alterations in the corneal endothelial layer two years after the implantation of iris claw phakic lenses. STUDY DESIGN: Prospective study of postoperative results with a minimum follow-up of 6 months, maximum of two years and a mean of 14 months. SETTING: Department of Ophthalmology, ‘La Fe’ University Hospital, Department of Surgery of Valencia School of Medicine, Valencia, Spain. PATIENTS: Ninety eyes of 70 patients presenting high myopia who underwent anterior chamber phakic lens implantation with iris fixation IOLs in the last two years. MAIN OUTCOME MEASURES: Non-contact specular microscopy with video image system was used to perform examination of the corneal e…

Dermatosis Neglecta or Terra Firma-Forme Dermatosis

2012

The Harderian Gland of the Djungarian Hamster (<i>Phodopus sungorus</i>): Light- and Electron-Microscopical Investigations

1993

The Harderian gland of the Djungarian hamster Phodopus sungorus was investigated by light and electron microscopy in adult animals of both sexes, held under either long or short photoperiods. These glands have a tubuloalveolar structure. Epithelial cells were seen as small cylindric cells with a large, round nucleus located basally, many small vacuoles distributed throughout the cytoplasm (type I cells) or as rather broad cells with larger vacuoles (type II cells). The ratio of both cell types differed from 1:1 to 2:1 (type I:type II), regardless of the animal’s sex. In the electron microscope, abundant smooth endoplasmic reticulum of the vesicular type and rod-like or oval-shaped mitochond…

LATE-BREAKING ABSTRACT: Comparative studies on bronchuswall-thickness by histologic and computed tomographic measurements of porcine lungs

2015

Aims: Histologic slides are commonly used as template in the evaluation and development of medical imaging methods.Diseases like Asthma and COPD show characteristic changes in airway morphology and airway measurement by computed tomography is a promising diagnostic approach.However,shrinkage caused by fixation and histological processing is known in lung tissue.In this study,the thickness of bronchus walls in paraffin and frozen sections as well as in CT and MicroCT were compared. Methods: Airway measurements of swine lungs were performed after freezing in ventilated condition in liquid nitrogen by measuring the wall thickness of 7 bronchi via CT and MicroCT as well as in frozen and paraffi…

On the value and limitations of liver histology in assessing non-alcoholic steatohepatitis

2020

Biochemical and histological alterations of cellular metabolism from jerboa (Jaculus orientalis) by 2,4-dichlorophenoxyacetic acid: Effects on d-3-hy…

2007

?; International audience; 2,4-Dichlorophenoxyacetic acid (2,4D) is one of the widely used herbicide of the phenoxy family with possible startling number of adverse effects on species other than the weeds which is designed to kill. The effects of 2,4D were investigated in jerboa (Jaculus orientalis), a wild animal of subdesert highlands. The jerboas have been daily treated intraperitonally with 2,4D 3 mg/kg body weight for 4 weeks. Plasmatic markers, and antioxidants defences systems were assessed and histological alterations were evaluated. The in vivo and in vitro effects of 2,4D on the mitochondrial D-3-hydroxybutyrate dehydrogenase (BDH) were also determined. Our results showed a strong…

Improvement of quality of life during treatment with anabolic therapy: Results of a multicenter study

2012

Efficacy and safety of daily treatment with parathyroid hormone were evaluated in a typical Italian population with severe post-menopausal osteoporosis eligible to anabolic treatment (Nota 79 AIFA). Materials and methods: 204 ambulatory female patients (median age: 72.6±8.3 years; height: 155.3±6.5 cm; weight: 61.1±11.9 Kg) with severe post-menopausal osteoporosis have been enrolled in this study accordingly to summary of product characteristics and Italian reimbursement criteria for osteoporosis drugs (Nota 79 AIFA), between January 2008 and April 2009 (Last Patient Out: October 2010). 146 (71.57%) out of these patients completed the study.6 visits were planned in the study protocol: basel…

The Val432Leu polymorphism of the CYP1B1 gene is associated with differences in estrogen metabolism and bone density.

2009

Polymorphisms of the CYP450 genes that encode for the enzymes that metabolize estrogen are linked to hormone-related cancers. We investigated the impact of two polymorphisms of the CYP1B1 gene previously reported to be associated with hormone-related disorders on estrogen metabolism and bone mineral density (BMD), another hormone-dependent condition, in women from different ethnic backgrounds. Four hundred sixty-eight postmenopausal Caucasian women, 220 from St. Louis, MO, USA (mean age=63.5+/-0.53 years) and 248 from Palermo, Italy (mean age=72.9+/-0.44 years) participated in the study. Measurements of urinary estrogen metabolites by enzyme-linked immunoassay, serum estradiol by ultrasensi…