Search results for "Histomorphometry"
showing 3 items of 3 documents
Drilling dimension effects in early stages of osseointegration and implant stability in a canine model
2015
Background: This study histologically evaluated two implant designs: a classic thread design versus another specifically designed for healing chamber formation placed with two drilling protocols. Material and Methods: Forty dental implants (4.1 mm diameter) with two different macrogeometries were inserted in the tibia of 10 Beagle dogs, and maximum insertion torque was recorded. Drilling techniques were: until 3.75 mm (regular-group); and until 4.0 mm diameter (overdrilling-group) for both implant designs. At 2 and 4 weeks, samples were retrieved and processed for histomorphometric analysis. For torque and BIC (bone-to-implant contact) and BAFO (bone area fraction occupied), a general-linea…
Profilin 1 negatively regulates osteoclast migration in postnatal skeletal growth, remodeling, and homeostasis in mice
2019
ABSTRACT Profilin 1 (Pfn1), a regulator of actin polymerization, controls cell movement in a context‐dependent manner. Pfn1 supports the locomotion of most adherent cells by assisting actin‐filament elongation, as has been shown in skeletal progenitor cells in our previous study. However, because Pfn1 has also been known to inhibit migration of certain cells, including T cells, by suppressing branched‐end elongation of actin filaments, we hypothesized that its roles in osteoclasts may be different from that of osteoblasts. By investigating the osteoclasts in culture, we first verified that Pfn1‐knockdown (KD) enhances bone resorption in preosteoclastic RAW264.7 cells, despite having a compa…
Osseointegration of miniscrews: a histomorphometric evaluation.
2007
SUMMARY Mini-implants and miniscrews are commonly used in orthodontics to provide additional temporary intraoral anchorage. Partial osseointegration represents a distinct advantage in orthodontic applications, allowing effective anchorage to be combined with easy insertion and removal. This article reports the histomorphometric fi ndings of the osseointegration of bracket screw bone anchors (BSBAs). In an experimental animal study, four BSBAs were inserted in the alveolar process of the lower jaw in each of fi ve male beagle dogs, aged 6.5 months from the same mother. Eleven screws were lost during the study, nine of them due to lack of primary stability. One screw was removed at the end of…