Search results for "History"

showing 10 items of 18523 documents

Ancient cattle genomics, origins, and rapid turnover in the Fertile Crescent

2019

Cattle were domesticated ∼10,000 years ago, but analysis of modern breeds has not elucidated their origins. Verdugo et al. performed genome-wide analysis of 67 ancient Near Eastern Bos taurus DNA samples. Several populations of ancient aurochs were progenitors of domestic cows. These genetic lineages mixed ∼4000 years ago in a region around the Indus Valley. Interestingly, mitochondrial analysis indicated that genetic material likely derived from arid-adapted Bos indicus (zebu) bulls was introduced by introgression.Science, this issue p. 173Genome-wide analysis of 67 ancient Near Eastern cattle, Bos taurus, remains reveals regional variation that has since been obscured by admixture in mode…

0301 basic medicine010506 paleontologyMitochondrial DNA[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and Prehistory1103Human Migration12041105IntrogressionZoologyGenomics01 natural sciencesDNA Mitochondrial[SHS]Humanities and Social SciencesDomesticationEvolution Molecular03 medical and health sciencesBronze AgeAnimals[SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry Molecular Biology/Biochemistry [q-bio.BM]Domestication0105 earth and related environmental sciences[SDV.EE]Life Sciences [q-bio]/Ecology environment[SDV.GEN]Life Sciences [q-bio]/GeneticsMultidisciplinaryGenomebiologyHuman migrationbusiness.industryGenomicsAurochsZebubiology.organism_classificationhumanities030104 developmental biologyFertilityCattlebusiness
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Overview of the History of the Cranial Nerves: From Galen to the 21st Century

2018

Throughout history the description and classification of the cranial nerves has been linked to the development and characteristics of anatomy and the role that it played as a tool in providing rationality to medicine, together with social, cultural, religious, and philosophical factors. Anatomists were interested in the cranial nerves, but they disagreed on their number and their paths. We can divide the history of the cranial nerves into three different periods: the first, early or macroscopic period; the second or microscopic period; and the third period or ontogenesis and genoarchitecture. The main aim of this article is to show how the description and knowledge of the cranial nerves wer…

0301 basic medicine03 medical and health sciences030104 developmental biology0302 clinical medicineHistologyHistoryCranial nervesAnatomyAnatomyDoctoral dissertation030217 neurology & neurosurgeryEcology Evolution Behavior and SystematicsBiotechnologyThe Anatomical Record
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A reconciliation with Darwin? Divergent views on evolutionism in Erich Wasmann and Jaime Pujiula, biologists and Jesuits

2016

A diferencia del cas Galileu, l’esglesia Catolica ha gestionat amb discrecio el pensament evolucionista i les obres de Charles Darwin. Entre els cientifics catolics, hi trobem defensors d’un evolucionisme amanit amb remarcables excepcions relacionades amb l’origen divi de la vida i de l’especie humana. L’entomoleg i jesuita Erich Wasmann arriba a la conclusio que la teoria evolutiva podia donar explicacio a les seues observacions sobre els mirmecofils i adopta un evolucionisme catolicament matisat que Ernst Haeckel considerava fraudulent pero molt perillos. El bioleg i jesuita catala Jaume Pujiula segui l’obra de Wasmann tot i prenent posicions ideologiques mes radicals que la de l’entomole…

0301 basic medicine03 medical and health sciences030104 developmental biologyMultidisciplinaryCharles darwinHistory and Philosophy of ScienceDarwin (ADL)PhilosophyEvolutionismHumanitiesMètode Revista de difusió de la investigació
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History and reality of the genus 'Homo' : what is it and why do we think so?

2017

Paleoanthropologists who worry about how nature is organized into species, and about what we should call them, are very often accused by their peers of «just arguing about names». This implies that basic taxonomy is a boring clerical operation that should be dispensed with as quickly as possible or even ignored, so that we can get to the really interesting questions about human evolution. Yet the reality is that we shall never understand the events of the intricate human evolutionary play if we cannot accurately identify the actors who participated in that drama. This article looks briefly at how our current supremely woolly concept of the genus Homo has come about, as background for urging…

0301 basic medicine03 medical and health sciences030104 developmental biologyMultidisciplinaryHistory and Philosophy of ScienceHuman evolutionBiologyHumanitiesDramaEpistemology
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Out of a creative jumble of ideas in the middle of last Century: Wiener, interdisciplinarity, and all that

2015

Is Biophysics an interdisciplinary science? In order to answer this rhetorical question, it can be useful to look back at history of disciplines, as well as that of the scientific institutions helping their development. In this contribution some aspects of the unusual hodgepodge of concepts involving Biophysics, the legacy of Cybernetics, cognitive science and the central figure of Norbert Wiener are presented and discussed.

0301 basic medicine030103 biophysicsChemistryOrganic ChemistryBiophysicsInterdisciplinarityHistory 20th CenturyBiochemistryEpistemology03 medical and health sciencesBiophysicRhetorical questionHumansCyberneticsCyberneticCyberneticsOrder (virtue)Human
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"The human use of human beings": Interdisciplinarity, transdisciplinarity and all that in biophysics and beyond.

2017

Abstract Biophysics, just by looking at its name, indicates an interdisciplinary scientific activity, although the notion of interdisciplinarity, as such, seems to be not widely or specifically discussed by biophysicists. The same seems to have happened as well in the early stages of the development of cybernetics, notably in Norbert Wiener's writings. This situation seems to contrast with what has happened in subsequent developments of cybernetics ideas, notably in general system theory and cognitive sciences. After a few general reflections on the notion of interdisciplinarity, its sophisticated variants and the path leading to the birth of cognitive science, we shall refer to Wiener's th…

0301 basic medicine030103 biophysicsSettore INF/01 - InformaticaChemistryOrganic ChemistryInterdisciplinarityBiophysicsSettore MAT/01 - Logica MatematicaHistory 20th CenturyBiochemistry03 medical and health sciencesBiophysicHuman useTransdisciplinarityWienerBiophysicsCyberneticsHumansCyberneticSocial responsibilityCyberneticsScientific activityHumanInterdisciplinarityBiophysical chemistry
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Consequences of single-locus and tightly linked genomic architectures for evolutionary responses to environmental change

2020

AbstractGenetic and genomic architectures of traits under selection are key factors influencing evolutionary responses. Yet, knowledge of their impacts has been limited by a widespread assumption that most traits are controlled by unlinked polygenic architectures. Recent advances in genome sequencing and eco-evolutionary modelling are unlocking the potential for integrating genomic information into predictions of population responses to environmental change. Using eco-evolutionary simulations, we demonstrate that hypothetical single-locus control of a life history trait produces highly variable and unpredictable harvesting-induced evolution relative to the classically applied multi-locus mo…

0301 basic medicineAcademicSubjects/SCI011400106 biological sciencesLinkage disequilibriumMultifactorial Inheritanceevolutionary simulationEnvironmental changeGenetic LinkageJhered/401 natural sciencesGenetics (clinical)recombination rate0303 health scienceseducation.field_of_studystructural genomic variationInheritance (genetic algorithm)Adaptation PhysiologicalBiological Evolutionclimate changePerspectiveTraitympäristönmuutoksetBiotechnologyPopulationevoluutioEnvironmentBiology010603 evolutionary biologyLife history theory03 medical and health sciencesVDP::Matematikk og Naturvitenskap: 400::Basale biofag: 470GeneticsEvolutionary dynamicseducationMolecular BiologySelection (genetic algorithm)030304 developmental biologygeenitModels GeneticGenetic Driftilmastonmuutoksetgenetic architectureGenetic architectureEditor's Choice030104 developmental biologyEvolutionary biologyperimäGene-Environment InteractionAdaptationlinkage disequilibrium
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Women's socioeconomic position in ontogeny is associated with improved immune function and lower stress, but not with height

2020

AbstractImmune function, height and resource accumulation comprise important life history traits in humans. Resource availability models arising from life history theory suggest that socioeconomic conditions influence immune function, growth and health status. In this study, we tested whether there are associations between family income during ontogeny, adult height, cortisol level and immune response in women. A hepatitis B vaccine was administered to 66 young Latvian women from different socioeconomic backgrounds, and blood samples were then collected to measure the level of antibodies that the women produced in response to the vaccination. Cortisol levels were measured from plasma sample…

0301 basic medicineAdultHepatitis B vaccineHydrocortisoneOntogenyBiological anthropologyPhysiologylcsh:MedicineBiologyFamily incomeEvolutionary ecologyArticleLife history theory03 medical and health sciencesYoung Adult0302 clinical medicineImmune systemHumansWomenHepatitis B Antibodieslcsh:ScienceSocioeconomic statusMultidisciplinarylcsh:RImmunityLatviaVaccination030104 developmental biologySocial ClassSocioeconomic Factorsbiology.proteinFemalelcsh:QAntibody030217 neurology & neurosurgeryStress PsychologicalCortisol ; Immune function ; Life history theory ; Sexual dimorphism ; Stress
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The torso integration hypothesis revisited in Homo sapiens: Contributions to the understanding of hominin body shape evolution.

2018

Objectives: Lower thoracic widths and curvatures track upper pelvic widths and iliac blades curvatures in hominins and other primates (torso integration hypothesis). However, recent studies suggest that sexual dimorphism could challenge this assumption in Homo sapiens. We test the torso integration hypothesis in two modern human populations, both considering and excluding the effect of sexual dimorphism. We further assess covariation patterns between different thoracic and pelvic levels, and we explore the allometric effects on torso shape variation. Material and Methods: A sex-balanced sample of 50 anatomically connected torsos (25 Mediterraneans, 25 Sub-Saharan Africans) was segmented fro…

0301 basic medicineAdultMaleBlack PeopleComputed tomographyBiologyModels BiologicalWhite PeopleAnthropology Physical03 medical and health sciencesSexual dimorphismImaging Three-DimensionalmedicineBody SizeHumans0601 history and archaeologyMorphometricsGeometric morphometricsAllometrySex Characteristics060101 anthropologymedicine.diagnostic_testintegumentary systemAnthropometryTorso06 humanities and the artsAnatomyTorsoBiological EvolutionSexual dimorphismbody regions030104 developmental biologymedicine.anatomical_structureBody shapeHomo sapiensAnthropologyFemaleAllometryAnatomyTomography X-Ray ComputedAmerican journal of physical anthropology
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Clinical course of sly syndrome (mucopolysaccharidosis type VII).

2016

WOS: 000377110800007

0301 basic medicineAdultMalePediatricsmedicine.medical_specialtyAdolescentMucopolysaccharidosisSly syndromeHepatosplenomegalyMetabolic disordersMucopolysaccharidosis VIIMedical and Health Sciences03 medical and health sciencesYoung Adult0302 clinical medicineHydrops fetalisSurveys and QuestionnairesmedicineGeneticsHumansMedical history1506Clinical geneticsFamily historyPreschoolChildGenetics (clinical)GlucuronidaseGenetics & Hereditybusiness.industryGenotype-Phenotype CorrelationsMucopolysaccharidosis VIIInfantEnzyme replacement therapyBiological Sciencesmedicine.diseaseLysosomal Storage Diseases030104 developmental biologyPhenotypeClinical genetics Genetics Metabolic disordersChild PreschoolFemalemedicine.symptombusiness030217 neurology & neurosurgeryMPS ; lysosomal storage disease ; β-glucuronidase
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