Search results for "Holisme"

showing 9 items of 9 documents

The Effects of N-Acetylcysteine on the Rat Mesocorticolimbic Pathway: Role of mGluR5 Receptors and Interaction with Ethanol

2021

N-acetylcysteine (NAC) is a prodrug that is marketed as a mucolytic agent and used for the treatment of acetaminophen overdose. Over the last few decades, evidence has been gathered that suggests the potential use of NAC as a new pharmacotherapy for alcohol use disorder (AUD), although its mechanism of action is already being debated. In this paper, we set out to assess both the potential involvement of the glutamate metabotropic receptors (mGluR) in the possible dual effect of NAC administered at two different doses and NAC’s effect on ethanol-induced activation. To this aim, 30 or 120 mg/kg of NAC was intraperitoneally administered to rats with the presence or absence of the negative allo…

0301 basic medicinePharmaceutical ScienceglutamatePharmacologyAcetylcysteine03 medical and health sciencesPharmacy and materia medica0302 clinical medicineNeurochemicalDrug Discoverymental disordersmedicinealcoholismMetabotropic glutamate receptor 5ChemistryCommunicationRGlutamate receptor<i>N</i>-acetylcysteineN-acetylcysteineRS1-441030104 developmental biologyMetabotropic receptorMTEPMechanism of actionMetabotropic glutamate receptorAlcoholismeMedicineMolecular Medicinemedicine.symptomTecnologia farmacèuticaMedicaments030217 neurology & neurosurgerymedicine.drugPharmaceuticals
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Physiological and Psychological Effects of a High Dose of Alcohol in Young Men and Women

2014

The objective of this study was to evaluate the effects of a high dose of alcohol on physiological and psychological parameters in young men and women with a previous history of alcohol consumption. Systolic and diastolic blood pressure, heart rate, state anxiety, attention, time estimation and manual dexterity were registered before (phase 1) and after (phase 2) intake of alcohol (38.4 g) or a non-alcoholic beverage. Trait anxiety was registered in phase 2 only. The results showed that acute consumption of a high dose of alcohol: i) improves attention in men (although the performance of alcohol consumers was not better than that of non-consumers); ii) blocks the systolic blood pressure hab…

Alcoholisme
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Forms and functions of Hundertwasser's writings

2018

The research focuses on the abundant writing of Hundertwasser and its place in the positioning of this actor of artistic renewal. He is recognized for his singular "work-life", since, aiming to upset society, he has expanded his field, from painting to ecology, via architecture. Starting from the geohistorical context, from the pictorial background of the beginning of the 20th century, the theories of 20th-century German scientists and "prophets" and the emergence of environmental movements, it is a question of studying the many poems, stories, speeches, manifestos, interventions in the media and comments, where Hundertwasser exposes and develops his convictions. The aim is to show that the…

Artistic avant-GardeÉcologie[SHS.LITT]Humanities and Social Sciences/LiteratureFar EastEcologyHolismAvant-Gardes artistiquesManifestes[SHS.LITT] Humanities and Social Sciences/LiteratureProse & poésieProse & poetryHolismeManifestosExtrême-Orient
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L'enfocament centrat en la persona des de la perspectiva holística i ecològica

2016

espanolDesde una vision global de la realidad humana, el articulo aborda la complejidad de la sinergia de la tendencia actualizante, para alcanzar el desarrollo y propone, desde la perspectiva holistica y ecologica, unas reflexiones epistemologicas y metodologicas, para afrontar la complejidad de los fenomenos humanos. Las consideraciones realizadas nos conducen al dialogo y la comunicacion, como el instrumento mas eficaz para el estudio de lo humano. Finalmente se presentan los resumenes de algunos trabajos realizados desde esta perspectiva. catalaDes d’una visio global de la realitat humana, l’article aborda la complexitat de la sinergia de la tendencia actualitzant de l’organisme, per ac…

Enfocament Centrat en la Persona epistemologia mètode fenomenològic holisme ecologia ArtículoGeneral Earth and Planetary Sciences:PSICOLOGÍA [UNESCO]UNESCO::PSICOLOGÍAGeneral Environmental Science
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Bipolar disorder comorbid with alcohol use disorder: focus on neurocognitive correlates

2015

Bipolar disorder (BD) and alcohol use disorders (AUDs) are usually comorbid, and both have been associated with significant neurocognitive impairment. Patients with the BD-AUD comorbidity (dual diagnosis) may have more severe neurocognitive deficits than those with a single diagnosis, but there is paucity of research in this area. To explore this hypothesis more thoroughly, we carried out a systematic literature review through January 2015. Eight studies have examined the effect of AUDs on the neurocognitive functioning of BD patients. Most studies found that BD patients with current or past history of comorbid AUDs show more severe impairments, especially in verbal memory and executive cog…

PHYSIOLOGY (MEDICAL)medicine.medical_specialtyStagingPhysiologyBipolar disorderneurocognitionAddictionReviewAlcohol use disorderComorbiditylcsh:PhysiologyAlcohol use disordersComorbiditatalcohol use disordersPhysiology (medical)mental disordersmedicineManic-depressive illnessBipolar disorderPsychiatryPHYSIOLOGYNeurocognitionbipolar disorderTrastorn bipolarlcsh:QP1-981business.industryCognitionsystems biologystagingmedicine.diseaseComorbidityAlcoholismcomorbiditySystems Biology.Systematic reviewAlcoholismeDual diagnosisaddictionVerbal memorybusinessSystems biologyNeurocognitive
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AUDIT, AUDIT-C y AR2I para evaluar el Binge Drinking en universitarios españoles

2020

La identificación de los jóvenes que realizan un consumo intensivo de alcohol (CIA) es una prioridad en el ámbito de la prevención e intervención, dadas las consecuencias bio-psico-sociales que genera. Objetivo. Verificar qué versión del AUDIT constituye el instrumento de screening más adecuado en esta población, partiendo de una operacionalización más precisa del CIA. Método. Se ha realizado un muestreo de conveniencia en el que han participado 190 jóvenes consumidores de alcohol entre 18 y 22 años (73.7% mujeres), que cumplimentaron un autoregistro de consumo de alcohol, el AUDIT y AR2I. Resultados. El análisis de conglomerados por sexos muestra 5 grupos de jóvenes CIA, en función de la e…

Psychiatry and Mental healthHealth (social science)JovesAlcoholismeDevelopmental and Educational Psychology
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Predictors of weekly alcohol drinking and alcoholrelated problems in binge-drinking undergraduates

2015

Texto en inglés e español Las importantes implicaciones que genera el consumo intensivo de alcohol entre los jóvenes justifican el interés por determinar qué factores predicen su aparición. Concretamente, en este estudio se analiza el papel de la personalidad y edad de inicio en el consumo de alcohol en la predicción del consumo semanal de alcohol, y de todas estas variables en la predicción del número de consecuencias asociadas al consumo en jóvenes universitarios. Se evalúan 213 consumidores intensivos de primer curso de la Universidad Complutense de Madrid. Todos ellos cumplimentaron un autoregistro de consumo, el BIS-11, el NEO-FFI y el IECI de consecuencias asociadas a la ingesta. Los …

Universitarios binge drinkingAlcohol Efectes fisiològicsJovesMedicine (miscellaneous)ConsecuenciasUniversity studentsPsychiatry and Mental healthConsumo intensivo de alcoholAlcoholismePersonalidadEdad inicioConsequencesDrinking onsetPersonality
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Epistemologia empirista sense dogmes

1989

Josep Lluís Blasco critica en aquest article la concepció fonamentista del coneixement, d’arrel cartesiana i basada, sobretot, en el dogma empirista que afirma que els enunciats, als que classifica segons la dicotomia analític-sintètic, poden tenir confirmació o refutació aïlladament, en suposar un atomisme semàntic que defensa que tot enunciat amb significat és reductible a un enunciat sobre la experiència immediata. Per tal de realitzar la seua crítica, que té com a blanc principal l’empirisme tradicional, el Wittgenstein del Tractatus i el positivisme lògic, Blasco es basa en Quine, Tarsky i el segon Wittgenstein i defensa un holisme semàntic, ontològic i epistemològic. Segons el holisme…

holisme epistemològicUNESCO::FILOSOFÍAholisme semànticholisme ontològic:FILOSOFÍA [UNESCO]atomisme semànticempirismefonamentismepositivisme lògicdicotomia analític-sintètic
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L'euro à la lumière des théories monétaires holistes contemporaines

2008

The thesis begins by explaining, in a first part, the genealogy of a heterodox tradition called “holist monetary approach”, which refuses dichotomic theories and the classical conception of the veil of money. It shows the proximities of these positions with a tradition consisting in thinking money as a “total social fact” involving far more than the three usual economic functions attributed to money. Recent research works conducted in France around Aglietta and Orléan fit in with this tradition. The thesis also leans on theories developed in Keynes' wake, sharing with the “social fact” approaches a holist methodology. The latter involves a main focus on macroeconomic analysis, which is, in …

institutionnalismepolitique monétaireBanque Centrale EuropéenneEuromonetary policy[SHS.ECO]Humanities and Social Sciences/Economics and FinanceEuropean Central Bankmacroéconomie post-keynésiennepost-Keynesian macroeconomics[ SHS.ECO ] Humanities and Social Sciences/Economies and financesholisminstitutionalismholisme[SHS.ECO] Humanities and Social Sciences/Economics and Finance
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