Search results for "Host"
showing 10 items of 1982 documents
Parasite virulence when the infection reduces the host immune response.
2010
Parasite infections often induce a reduction in host immune response either because of a direct manipulation of the immune system by the parasite or because of energy depletion. Although infection-induced immunodepression can favour the establishment of the parasite within the host, a too severe immunodepression may increase the risk of infection with opportunistic pathogens, stopping the period over which the parasite can be transmitted to other hosts. Here, we explore how the risk of contracting opportunistic diseases affects the survival of the amphipod Gammarus pulex infected by the acanthocephalan Pomphorhynchus laevis . Previous work with this system has shown that upon infection, G.…
Density-dependent effects on parasite growth and parasite-induced host immunodepression in the larval helminth Pomphorhynchus laevis.
2011
SUMMARYLarval helminths exploit the physiology of their intermediate hosts: first, as a resource for energy and space and second by altering the immune system activity to ensure their survival. Whereas the growth pattern under parasite competition has been investigated, the effect of multiple infections on the level of parasite-induced immunodepression in a trophically transmitted helminth has been neglected. In this study, amphipodsGammarus pulexwere infected in the laboratory by the acanthocephalanPomphorhynchus laevisto investigate how parasite density in the intermediate host affected (i) cystacanth growth and (ii) the level of parasite-induced alterations of the host immune defences, t…
Bacterial load and inflammatory response in sputum of alpha-1 antitrypsin deficiency patients with COPD
2019
Bruno Balbi,1 Claudia Sangiorgi,1 Isabella Gnemmi,1 Ilaria Ferrarotti,2 Davide Vallese,1 Elena Paracchini,1 Lorena Delle Donne,1 Luciano Corda,3 Paolo Baderna,4 Angelo Corsico,2 Mauro Carone,1 Paola Brun,5 Francesco Cappello,6,7 Fabio LM Ricciardolo,8 Paolo Ruggeri,9 Sharon Mumby,10 Ian M Adcock,10 Gaetano Caramori,9 Antonino Di Stefano11Istituti Clinici Scientifici Maugeri, IRCCS, Division of Pneumology and Laboratory of Cytoimmunopathology of the Heart and Lung, Veruno, Italy; 2Department of Internal Medicine and Medical Therapy, University of Pavia, Pavia, Italy; 3Medicina Respiratoria, Seconda Medicina Interna, Spedali Civili, Brescia, Italy; 4Division of Pneumology, Aosta Hospital, Aos…
Intestinal Helminth Fauna of Bottlenose DolphinTursiops truncatusand Common DolphinDelphinus delphisfrom the Western Mediterranean
2012
We report on the intestinal helminth fauna of 15 bottlenose dolphins Tursiops truncatus and 6 short-beaked common dolphins Delphinus delphis from the western Mediterranean. Eight helminth species were found in bottlenose dolphin, i.e., the digeneans Synthesium tursionis, Brachycladium atlanticum, and Pholeter gastrophilus, the nematode Anisakis sp., and the cestodes Tetrabothrius forsteri, Diphyllobothrium sp., Strobilocephalus triangularis, and tetraphyllidean plerocercoids. Brachycladium atlanticum, S. triangularis , and tetraphyllidean plerocercoids are new host records. No T. forsteri had previously been reported in Mediterranean bottlenose dolphins. Three species of helminths were reco…
A new species of the genus Spiroxys (Nematoda: Gnathostomatidae) from Madagascan pleurodiran turtles (Pelomedusidae)
2008
AbstractSpiroxys ankarafantsika, sp. nov. is described from Madagascar in two species of freshwater turtles, Pelusios castanoides and Pelomedusa subrufa. Spiroxys ankarafantsika differs from other species of the genus in having pseudolabial teeth only on the median lobes and no other cuticular prominences, a smooth cuticular collar, deirides as cervical minute spine-like projections, and a gubernaculum without tubes. This is the first record of a nominal species of the genus Spiroxys from the Ethiopian region.
Oh sister, where art thou? Spatial population structure and the evolution of an altruistic defence trait.
2014
The evolution of parasite virulence and host defences is affected by population structure. This effect has been confirmed in studies focusing on large spatial scales, whereas the importance of local structure is not well understood. Slavemaking ants are social parasites that exploit workers of another species to rear their offspring. Enslaved workers of the host species Temnothorax longispinosus have been found to exhibit an effective post-enslavement defence behaviour: enslaved workers were observed killing a large proportion of the parasites’ offspring. As enslaved workers do not reproduce, they gain no direct fitness benefit from this ‘rebellion’ behaviour. However, there may be an indir…
Ant Societies Buffer Individual-Level Effects of Parasite Infections
2012
Parasites decrease host fitness and can induce changes in host behavior, morphology, and physiology. When parasites exploit social insects, they influence not only infected individuals but also the society as a whole. Workers of the ant Temnothorax nylanderi are an intermediate host for the cestode Anomotaenia brevis. We studied a heavily parasitized population and found that, although parasite infection had strong and diverse consequences for individual workers, colony fitness remained unchanged. At the individual level, we uncovered differences among the three worker types, infected and healthy workers from parasitized colonies and healthy workers from nonparasitized colonies. Infected wo…
Linking Human Milk Oligosaccharides, Infant Fecal Community Types, and Later Risk To Require Antibiotics
2020
Human milk is the sole and recommended nutrition for the newborn infant and contains one of the largest constituents of diverse oligosaccharides, dubbed human milk oligosaccharides (HMOs). Preclinical and clinical association studies indicate that HMOs have multiple physiological functions largely mediated through the establishment of the gut microbiome. Until recently, HMOs were not available to investigate their role in randomized controlled intervention trials. To our knowledge, this is the first report on the effects of 2 HMOs on establishing microbiota in newborn infants. We provide a detailed description of the microbiota changes observed upon feeding a formula with 2 HMOs in comparis…
Acanthocephalan size and sex affect the modification of intermediate host colouration
2009
Parasitology, 136 (8)
Altered Protein Expression in the Ileum of Mice Associated with the Development of Chronic Infections with Echinostoma caproni (Trematoda)
2015
Background Echinostoma caproni (Trematoda: Echinostomatidae) is an intestinal trematode that has been extensively used as experimental model to investigate the factors determining the expulsion of intestinal helminths or, in contrast, the development of chronic infections. Herein, we analyze the changes in protein expression induced by E. caproni infection in ICR mice, a host of high compatibility in which the parasites develop chronic infections. Methodology/Principal Findings To determine the changes in protein expression, a two-dimensional DIGE approach using protein extracts from the intestine of naïve and infected mice was employed; and spots showing significant differential expression…