Search results for "Human heart"
showing 3 items of 13 documents
Letter by Sacha and Feusette Regarding Article, “Dynamic Edematous Response of the Human Heart to Myocardial Infarction: Implications for Assessing M…
2018
We have read with a great interest the article by Fernandez-Jimenez et al presenting a bimodal edematous reaction of reperfused myocardium after ST-segment elevation myocardial infarction (STEMI).1 According to the study, the initial edema emerges early and disappears by 24 hours; however, the second edema appears between days 4 and 7 after reperfusion. The authors conclude that the assessment of …
Sustained reentry in a 3d regionally ischemic human heart. A simulation study
2016
In this work, we have studied the vulnerable window and propagation patterns in a human heart during acute ischemia. A 3-D biventricular model of a human heart with realistic heterogeneity and fiber orientations has been considered. The ischemic region was located in the anterior left ventricular wall mimicking the occlusion of the circumflex artery. The electrical activity of the tissue was modeled with the monodomain model along with a modified version of the ten Tusscher 2006 ionic model. The model predicts the generation of sustained re-entrant activity in the form of a rotor around the ischemic zone. Patterns in the form of figure-of-eight were also observed within the vulnerable windo…
Effect of Scar Development on Fast Electrophysiological Models of the Human Heart: In-Silico Study on Atlas-Based Virtual Populations
2011
The main goal of this work is to study the effect of scar development in the electrophysiological function of the human left ventricle by statistically analyzing large-scale simulation data including hypertrophic and dilated hearts. Electrophysiological simulations are obtained by solving the classical Eikonal equation in both the ventricular tissue and a customized Purkinje system. This Purkinje system is obtained assuming a geodesic rule to connect different Purkinje-myocardial junctions into a tree-like structure. Infarction shape and function is modeled with taking into account the occlusion in coronary arteries. Infarct, core and border zones of the scar are estimated by calculating bl…