Search results for "Hunting"

Guerra ideológica

2007

Impacto de la enfermedad de Huntington en la familia

2012

Se describen las alteraciones estructurales y emocionales de las familias con uno o más miembros enfermos de Huntington, en función de los diferentes síntomas, del afectado (descendientes, progenitores) y de las diferentes etapas. Consideramos que los servicios de ayuda a la familia deben estar compuestos por profesionales expertos en las necesidades específicas de esta enfermedad y que deben ayudar a planificar y diseñar las ayudas de manera individual, adecuada y flexible. Esta ayuda debe centrarse en superar el impacto de la enfermedad, en proporcionar información relevante, en buscar soluciones prácticas, en dar apoyo emocional, en diseñar los cuidados necesarios en cada caso y etapa, y…

Demos también buenas noticias

2006

Integrismo político en EEUU / 3. El peligro hispano

2004

Diseased Social Predators

2017

Social predators benefit from cooperation in the form of increased hunting success, but may be at higher risk of disease infection due to living in groups. Here, we use mathematical modeling to investigate the impact of disease transmission on the population dynamics benefits provided by group hunting. We consider a predator-prey model with foraging facilitation that can induce strong Allee effects in the predators. We extend this model by an infectious disease spreading horizontally and vertically in the predator population. The model is a system of three nonlinear differential equations. We analyze the equilibrium points and their stability as well as one- and two-parameter bifurcations. …

Palaeogenomics of Upper Palaeolithic to Neolithic European hunter-gatherers

2023

Acknowledgements: The authors thank G. Marciani and O. Jöris for comments on archaeology; C. Jeong, M. Spyrou and K. Prüfer for comments on genetics; M. O’Reilly for graphical support for Fig. 5 and Extended Data Fig. 9; the entire IT and laboratory teams at the Department of Archaeogenetics of MPI-SHH for technical assistance; M. Meyer and S. Nagel for support with single-stranded library preparation; K. Post, P. van Es, J. Glimmerveen, M. Medendorp, M. Sier, S. Dikstra, M. Dikstra, R. van Eerden, D. Duineveld and A. Hoekman for providing access to human specimens from the North Sea (The Netherlands); M. D. Garralda and A. Estalrrich for providing access to human specimens from La Riera (S…

Predatory habits of the grasshopper-hunting waspStizus continuus(Hymenoptera: Crabronidae): diet preference, predator–prey size relationships and for…

2009

In a coastal salt-marsh of Spain, the digger wasp Stizus continuus primarily hunted for grasshoppers of the genus Heteracris, revealing (at least in the period of the study and in this area) this wasp to be almost monophagous. In contrast, grasshoppers of the genus Acrotylus were ignored by the wasps in spite of their high abundance in the environment. We hypothesize that this bias occurred because Acrotylus is found more often on the soil and on grasses, while Heteracris is nearly only found on Sarcocornia bushes, which probably represent the habitat mostly exploited by the wasps for hunting. The greater variance in size of the prey collected by larger females produced weak wasp–prey size …

Ubiquitin-independent function of optineurin in autophagic clearance of protein aggregates.

2013

Summary Aggregation of misfolded proteins and the associated loss of neurons are considered a hallmark of numerous neurodegenerative diseases. Optineurin is present in protein inclusions observed in various neurodegenerative diseases including amyotrophic lateral sclerosis (ALS), Huntington's disease, Alzheimer's disease, Parkinson's disease, Creutzfeld-Jacob disease and Pick's disease. Optineurin deletion mutations have also been described in ALS patients. However, the role of optineurin in mechanisms of protein aggregation remains unclear. In this report, we demonstrate that optineurin recognizes various protein aggregates via its C-terminal coiled-coil domain in a ubiquitin-independent m…

Expression of genes encoding the calcium signalosome in cellular and transgenic models of Huntington's disease

2013

Huntington's disease (HD) is a hereditary neurodegenerative disease caused by the expansion of a polyglutamine stretch in the huntingtin (HTT) protein and characterized by dysregulated calcium homeostasis. We investigated whether these disturbances are correlated with changes in the mRNA level of the genes that encode proteins involved in calcium homeostasis and signaling (i.e., the calciosome). Using custom-made TaqMan low-density arrays containing probes for 96 genes, we quantified mRNA in the striatum in YAC128 mice, a model of HD, and wildtype mice. HTT mutation caused the increased expression of some components of the calcium signalosome, including calretinin, presenilin 2, and calmyri…

AAV Vector–mediated RNAi of Mutant Huntingtin Expression Is Neuroprotective in a Novel Genetic Rat Model of Huntington's Disease

2008

We report the characterization of a new rapid-onset model of Huntington's disease (HD) generated by adeno-associated virus (AAV) vector–mediated gene transfer of N-terminal huntingtin (htt) constructs into the rat striatum. Expression of exon 1 of mutant htt containing 70 CAG repeats rapidly led to neuropathological features associated with HD. In addition, we report novel data relating to neuronal transduction of AAV vectors that modulated the phenotype observed in this model. Quantitative reverse transcriptase–polymerase chain reaction (RT–PCR) revealed that AAV vector–mediated expression in the striatum increased by >100-fold as compared to the endogenous htt level. Moreover, AAV vectors…