Search results for "Hydrodynamics"

Bio-predictive tablet disintegration: Effect of water diffusivity, fluid flow, food composition and test conditions

2013

Abstract Food intake may delay tablet disintegration. Current in vitro methods have little predictive potential to account for such effects. The effect of a variety of factors on the disintegration of immediate release tablets in the gastrointestinal tract has been identified. They include viscosity of the media, precipitation of food constituents on the surface of the tablet and reduction of water diffusivity in the media as well as changes in the hydrodynamics in the surrounding media of the solid dosage form. In order to improve the predictability of food affecting the disintegration of a dosage form, tablet disintegration in various types of a liquefied meal has been studied under stati…

On the Consistency Restoring in SPH

2009

Smoothed particles hydrodynamics numerical simulations of droplets walking on viscous vibrating liquid

2016

We study the phenomenon of the "walking droplet", by means of numerical fluid dynamics simulations using the Smoothed Particle Hydrodynamics numerical method. This phenomenon occurs when a millimetric drop is released on the surface of an oil of the same composition, contained in a tank and subjected to vertical oscillations of frequency and amplitude very close to the Faraday instability threshold. At appropriate values of the parameters of the system under study, the oil droplet jumps permanently on the surface of the vibrating liquid forming a localized wave-particle system, reminding the behaviour of a wave particle quantum system as suggested by de Broglie. In our study, we made releva…

Inflow/outflow pressure boundary conditions for smoothed particle hydrodynamics simulations of incompressible flows

2017

Abstract Open Boundary treatment is a well-known issue in the Smoothed Particle Hydrodynamics (SPH) method, mainly when the truly Incompressible (ISPH) approach is employed. In the paper a novel method is proposed to set pressure boundary conditions in the computational domain inlets and outlets, without requiring the velocity profile assignment. The new technique allows to treat in the same way inflow and outflow sections, effectively dealing with the release of new particles at inlets and the deactivation of the ones leaving the domain through the outlets. Several 3D numerical tests, both in the laminar and turbulent regimes, are carried out to validate the proposed numerical scheme consi…

Grouping behaviour impacts on the parasitic pressure and squamation of sharks

2022

The evolution of grouping behaviour involves a complex trade-off of benefits and costs. Among the latter, an increase in the risk of parasitic transmission is a well-documented phenomenon that has likely promoted the evolution of defensive mechanisms in aquatic vertebrates. Here, we explore the relationship between grouping behaviour, parasitic richness (∼parasitic pressure), and the evolution of potential defensive traits in the squamation of sharks through phylogenetic, standard and zero-inflation regression models. Our results demonstrate that sharks that frequently aggregate show increased parasitic pressure, which may constitute an agent of selection. Accordingly, their squamation is c…

DNA delivery to 'ex vivo' human liver segments.

2011

Hydrodynamic injection is an efficient procedure for liver gene therapy in rodents but with limited efficacy in large animals, using an 'in vivo' adapted regional hydrodynamic gene delivery system. We study the ability of this procedure to mediate gene delivery in human liver segments obtained by surgical resection. Watertight liver segments were retrogradely injected from hepatic vein with a saline solution containing a plasmid bearing the enhanced green fluorescent protein (eGFP) gene, under different conditions of flow rate (1, 10 and 20 ml s(-1)) and final perfused volume. Samples were cultured for 1 to 2 days and used for microscopy and molecular analysis of gene expression. The fluore…

Relativistic simulations of rotational core collapse : II. Collapse dynamics and gravitational radiation

2002

We have performed hydrodynamic simulations of relativistic rotational supernova core collapse in axisymmetry and have computed the gravitational radiation emitted by such an event. Details of the methodology and of the numerical code have been given in an accompanying paper. We have simulated the evolution of 26 models in both Newtonian and relativistic gravity. Our simulations show that the three different types of rotational supernova core collapse and gravitational waveforms identified in previous Newtonian simulations (regular collapse, multiple bounce collapse, and rapid collapse) are also present in relativistic gravity. However, rotational core collapse with multiple bounces is only …

Searches for transverse momentum dependent flow vector fluctuations in Pb-Pb and p-Pb collisions at the LHC

2017

The measurement of azimuthal correlations of charged particles is presented for Pb-Pb collisions at $\sqrt{s_{\rm NN}}=$ 2.76 TeV and p-Pb collisions at $\sqrt{s_{\rm NN}}=$ 5.02 TeV with the ALICE detector at the CERN Large Hadron Collider. These correlations are measured for the second, third and fourth order flow vector in the pseudorapidity region $|��|<0.8$ as a function of centrality and transverse momentum $p_{\rm T}$ using two observables, to search for evidence of $p_{\rm T}$-dependent flow vector fluctuations. For Pb-Pb collisions at 2.76 TeV, the measurements indicate that $p_{\rm T}$-dependent fluctuations are only present for the second order flow vector. Similar results hav…

Magnetorotational core collapse of possible GRB progenitors – II. Formation of protomagnetars and collapsars

2020

We assess the variance of the post-collapse evolution remnants of compact, massive, low-metallicity stars, under small changes in the degrees of rotation and magnetic field of selected pre-supernova cores. These stellar models are commonly considered progenitors of long gamma-ray bursts. The fate of the proto-neutron star (PNS) formed after collapse, whose mass may continuously grow due to accretion, critically depends on the poloidal magnetic field strength at bounce. Should the poloidal magnetic field be sufficiently weak, the PNS collapses to a black hole (BH) within a few seconds. Models on this evolutionary track contain promising collapsar engines. Poloidal magnetic fields smooth over…

Termination of the magnetorotational instability via parasitic instabilities in core-collapse supernovae

2016

The magnetorotational instability (MRI) can be a powerful mechanism amplifying the magnetic field in core-collapse supernovae. Whether initially weak magnetic fields can be amplified by this instability to dynamically relevant strengths is still a matter of debate. One of the main uncertainties concerns the process that terminates the growth of the instability. Parasitic instabilities of both Kelvin-Helmholtz and tearing-mode type have been suggested to play a crucial role in this process, disrupting MRI channel flows and quenching magnetic field amplification. We perform two-dimensional and three-dimensional sheering-disc simulations of a differentially rotating protoneutron star layer in …