Search results for "Hydroxymethyl"

showing 3 items of 313 documents

Inhibition of Protein Isoprenylation Impairs Rho-Regulated Early Cellular Response to Genotoxic Stress

2000

Activation of c-Jun N-terminal kinases (JNKs) and nuclear factor-kappaB (NF-kappaB) are early cellular responses to genotoxic stress involved in the regulation of gene expression. Pretreatment of cells with the hydroxymethyl glutaryl-CoA reductase inhibitor lovastatin blocked stimulation of JNK1 activity by UV irradiation and by treatment with the alkylating compound methyl methanesulfonate but did not affect activation of extracellular signal-regulated kinase 2 by UV light. Lovastatin also attenuated UV-induced degradation of the NF-kappaB inhibitor IkappaBalpha. The effects of lovastatin on UV-triggered stimulation of JNK1 as well as on IkappaBalpha degradation were reverted by cotreatmen…

rho GTP-Binding ProteinsProtein PrenylationStimulationClostridium difficile toxin BCHO CellsGenotoxic StressBiologychemistry.chemical_compoundCricetinaemedicineAnimalsHumansMitogen-Activated Protein Kinase 8LovastatinPharmacologyMutagenicity TestsKinaseFarnesyltransferase inhibitorNF-kappa BMethyl methanesulfonateCell biologyIκBαchemistryMolecular MedicineLovastatinHydroxymethylglutaryl-CoA Reductase InhibitorsMitogen-Activated Protein KinasesHeLa CellsSignal Transductionmedicine.drugMolecular Pharmacology
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Task-Specific Organic Salts and Ionic Liquids Binary Mixtures: A Combination to Obtain 5-Hydroxymethylfurfural From Carbohydrates

2019

The increase in energy demand and depletion of fossil fuels are among major issues of modern society. Valorization and transformation of raw materials in products of industrial value represents a challenge. This justifies the growing interest of scientific research towards the identification of suitable media and methodologies able to pursue above goals, paying attention to matter of sustainability. On this subject, we studied sulfonic-acid functionalized diimidazolium salts as catalysts for the conversion of fructose and sucrose to 5-hydroxymethylfurfural (5-HMF) in an ionic liquid mixture. In general, using these salts allowed us to obtain 5-HMF in good yields from both substrates in mild…

task-specific organic saltsGreen chemistryCarbohydrate conversionSalt (chemistry)02 engineering and technologyRaw materialSulfonic acidIonic liquid010402 general chemistry01 natural sciences5-HMFCatalysislcsh:Chemistryionic liquidschemistry.chemical_compoundOrganic chemistryReactivity (chemistry)Sustainable chemistryOriginal Researchchemistry.chemical_classification5-hydroxymethylfurfuralTask Specific Ionic LiquidBiomass conversionChemistryGeneral ChemistrySettore CHIM/06 - Chimica Organica021001 nanoscience & nanotechnologyTask-specific organic salt0104 chemical sciencesChemistryHammett acidity functionlcsh:QD1-999Ionic liquid0210 nano-technology
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CCDC 1551425: Experimental Crystal Structure Determination

2018

Related Article: Eleni C. Mazarakioti, Sofia Tzani, Vassilis Psycharis, Michael Pissas, Yiannis Sanakis, Catherine P. Raptopoulou|2017|Curr.Inorg.Chem.|7|66|doi:10.2174/1877944107666170914113838

tris(mu-1-[{[1-hydroxy-2-(hydroxymethyl)-3-oxidopropan-2-yl]imino}methyl]naphthalen-2-olato)-tris(mu-benzoato)-tri-iron(iii) dichloromethane solvate hydrateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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