Search results for "Hypolaetin"

Hypolaetin-8-O-Glucoside, An Anti-inflammatory Flavonoid from Sideritis mugronensis.

1985

Selectivity of Neutrophil 5-Lipoxygenase and Cyclo-oxygenase Inhibition by an Anti-inflammatory Flavonoid Glycoside and Related Aglycone Flavonoids

1988

Abstract A newly described plant-derived flavonoid, hypolaetin-8-glucoside, which has anti-inflammatory and gastroprotective actions in-vivo, and its corresponding aglycone, hypolaetin, have been compared with 14 other flavonoids for inhibition of eicosanoid generation via the 5-lipoxygenase and cyclo-oxygenase pathways in elicited rat peritoneal leukocytes stimulated with calcium ionophore. Comparable results for the inhibitory profiles of the compounds were obtained using either radioimmunoassay of released eicosanoids or radio-TLC of metabolites formed from labelled arachidonate, but there were differences in absolute potency of the inhibitors. Hypolaetin-8-glucoside was a weak but selec…

Seasonal variation of hypolaetin 8-glucoside inSideritis mugronensis borja

1990

A quantitative analysis of the antiinflammatory flavonoid hypolaetin 8-glucoside from Sideritis mugronensis during an annual growth cycle was carried out. After an irregular increase in spring, the maximum levels were reached and maintained in early summer samples.