Search results for "I (ce)"

showing 10 items of 160 documents

Gli Studi di Storia romana a Messina e la figura di Lietta De Salvo fra XX e XXI secolo

2019

The article traces, through the scientific personality of the Professor Lietta De Salvo, the tradition of Roman History Studies at the University of Messina at the turn of the 20th and 21st centuries. The contribution is a tribute to the 80th birthday and career of a scholar whose name is linked to the most significant studies on Late Antiquity in Italy.

Late AntiquityXX-XXI certuriesLietta De SalvoSettore L-ANT/03 - Storia RomanaUniversity of MessinaRoman History
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Lesioni carotidee asintomatiche quale marker di futuri eventi cardiovascolari e cerebrovascolari nel follow-up a lungo termine: correlazione con gli …

2002

Lesioni carotidee eventi cardiovascolari eventi cerebrovascolari gli indici di flogosi le infezioni cytomegalovirus chlamydia pneumoniae helicobacter pylori
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SISTEMI VERDI COME CULTURA RIGENERATIVA: STRUMENTI E TECNOLOGIE

2021

The study analyzes and proposes in the historical and in the area immediately to it adjacent, the "values-nature" of the buildings through the creation of gardens wall and vertical gardens in the elevatiloy of non-monumental buildings. The study deepens in particular the specificity of the garden roof and the garden vertical, recognizing benefits and critical issues that distinguish these green systems for construction. It also deepens the concept of resilience in close relationship sustainability and regenerative design applied to the built environment. The theme of regenerative design is studied and promoted as an adaptive strategy at the design stage; it requires you to leave nature stre…

Lo studio analizza e propone nel centro storico e nell’area immediatamente ad esso adiacente la ”valori-naturazione” degli edifici attraverso la creazione di giardini pensili e di giardini verticali nei prospetti degli immobili non monumentali. Lo studio approfondisce in particolare le specificità del tetto giardino e del giardino verticale riconoscendo benefici e criticità che contraddistinguono questi sistemi verdi per l’edilizia. Si approfondisce inoltre il concetto di resilienza in stretta relazione alla sostenibilità e al regenerative design applicato all’ambiente costruito. Il tema del regenerative design viene studiato e promosso come strategia adattiva in fase di progettazioneesso richiede di lasciare che la natura rafforzi le sue capacità di autoguarigione e la sua integrità mediante l’uso di metodologie rigenerative integrate. Lo studio intende proporre una base su cui poter fondare ulteriori sviluppi scientifici sui sistemi di inverdimento esistenti o su brevetti in fase di sviluppo applicabili ai centri storici del territorio siciliano. Si prevede la redazione di un libretto divulgativo per gli abitanti volto alla disseminazione di una cultura del verde tecnologico ancora poco presente nei centri siciliani. Per quanto concerne le modalità attuative del progetto di ricerca sono state individuate: sia azioni orientate alla sensibilizzazione dei cittadini di Alcamo e dei residenti nella provincia sia l’individuazione di possibili forme di incentivazione per la mobilitazione di risorse private. Tale studio si inserisce nell’ambito di un filone di ricerca in itinere sui sistemi tecnologici di inverdimento per la costruzione di “Città parco” e di “Green hill” le cui linee guida e modalità attuative sono già state individuate dall’autrice per diversi comuni siciliani.Settore ICAR/12 - Tecnologia Dell'Architettura
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Enhanced proinflammatory response to the Candida albicans gpi7 null mutant by murine cells.

2008

International audience; The Candida albicans gpi7/gpi7 null mutant strain (Deltagpi7), which is affected in glycosylphosphatidylinositol (GPI) anchor biosynthesis, showed a reduced virulence following systemic infection of C57BL/6 mice. In vitro production of TNF-alpha, IL-6 and IL-1beta by macrophages in response to Deltagpi7 cells was significantly increased as compared to control (wild type GPI7/GPI7 and revertant gpi7/GPI7) cells; this probably contributes to the enhanced recruitment of neutrophils to the peritoneal cavity in response to Deltagpi7 cells. Survival of knockout mice for Toll-like receptor (TLR) 2 and TLR4 following intravenous injection of Deltagpi7 cells showed no signifi…

MESH: InflammationGlycosylphosphatidylinositolsNeutrophilsmedicine.medical_treatmentInterleukin-1betasourisMESH: NeutrophilsMESH: VirulenceMESH: Mice KnockoutMiceMESH: Interleukin-1betaNull cellMESH: AnimalsCandida albicansPeritoneal CavityCells CulturedMice Knockout0303 health sciencesToll-like receptorbiologyVirulenceMESH: Toll-Like Receptor 2MESH: Peritoneal CavityMESH: Toll-Like Receptor 4MESH: GlycosylphosphatidylinositolsInfectious DiseasesCytokineMESH: Survival AnalysisTumor necrosis factor alphaMESH: Fungal Proteinsprotéine de la paroi cellulaireMESH: Macrophages PeritonealMESH: Cells CulturedVirulence FactorsImmunologyMicrobiologyMicrobiologyProinflammatory cytokineFungal Proteins03 medical and health sciencesMESH: Mice Inbred C57BLmedicineAnimalsMESH: Mice030304 developmental biologyMESH: Virulence FactorsInflammation030306 microbiologyInterleukin-6Tumor Necrosis Factor-alphaMESH: Candida albicans[SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry Molecular Biology/Molecular biologybiology.organism_classificationSurvival AnalysispathogénicitéMESH: Interleukin-6Toll-Like Receptor 2Mice Inbred C57BLToll-Like Receptor 4TLR2GlycosylphosphatidylinositolMESH: Gene DeletionMESH: Tumor Necrosis Factor-alphaTLR4Macrophages Peritonealcandida albicansimmunitéGene Deletion
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Elevated Testosterone Level and Urine Scent Marking in Male 5xFAD Alzheimer Model Mice

2019

Background:Function of the Amyloid Precursor Protein (AβPP) and its various cleavage products still is not unraveled down to the last detail. While its role as a source of the neurotoxic Amyloid beta (Aβ) peptides in Alzheimer’s Disease (AD) is undisputed and its property as a cell attachment protein is intriguing, while functions outside the neuronal context are scarcely investigated. This is particularly noteworthy because AβPP has a ubiquitous expression profile and its longer isoforms, AβPP750 and 770, are found in various tissues outside the brain and in non-neuronal cells.Objective:Here, we aimed at analyzing the 5xFAD Alzheimer’s disease mouse model in regard to male sexual function.…

Male0301 basic medicinemedicine.medical_specialtymiceAmyloid betaCentral nervous system610Mice Transgenicamyloid precursor proteinAmyloid beta-Protein PrecursorSexual Behavior Animal03 medical and health sciences0302 clinical medicinesexual behaviorAlzheimer DiseaseInternal medicineTestisPresenilin-1medicineAmyloid precursor proteinAnimalsSperm CountbiologyWild typeBrainOrgan SizeAlzheimer's diseaseSertoli cellSpermPhenotypeAndrogen receptorDisease Models Animal030104 developmental biologymedicine.anatomical_structureEndocrinologyNeurologytestosteronebiology.proteinNeurology (clinical)030217 neurology & neurosurgeryurine scent marking test
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Nuclear localization of the protein encoded by the Wilms’ tumor gene WT1 in embryonic and adult tissues

1993

ABSTRACT The human Wilms’ tumor gene WT1 encodes a putative transcription factor implicated in tumorigenesis and in specifying normal urogenital development. We have studied the distribution of WT1 protein and mRNA using immunohistochemistry and in situ hybridization. Monoclonal antibodies were raised against a peptide specific to the first alternative splice site of WT1. Two antibodies specifically reacted on Western blot to this WT1 isoform. Immunofluorescence localized WT1 protein to podocytes during mesonephric and metanephric development. In situ hybridization revealed a similar pattern of expression except that WT1 mRNA was also present in metanephric blastema and renal vesicles. Mess…

MaleGene isoformcongenital hereditary and neonatal diseases and abnormalitiesmedicine.medical_specialtyBlotting WesternFluorescent Antibody TechniqueGene ExpressionUrogenital SystemIn situ hybridizationBiologyKidneyurologic and male genital diseasesPolymerase Chain ReactionInternal medicineGene expressionmedicineHumansRNA MessengerWT1 ProteinsMolecular BiologyTranscription factorIn Situ HybridizationCell NucleusMessenger RNAGranulosa CellsSertoli Cellsurogenital systemfungiZinc FingersWilms' tumormedicine.diseasefemale genital diseases and pregnancy complicationsWilms Tumor ProteinCell biologyDNA-Binding ProteinsCell nucleusmedicine.anatomical_structureEndocrinologyMesonephrosFemaleTranscription FactorsDevelopmental BiologyDevelopment
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Safety of primary anastomosis following emergency left sided colorectal resection: an international, multi-centre prospective audit

2018

Introduction: Some evidence suggests that primary anastomosis following left sided colorectal resection in the emergency setting may be safe in selected patients, and confer favourable outcomes to permanent enterostomy. The aim of this study was to compare the major postoperative complication rate in patients undergoing end stoma vs primary anastomosis following emergency left sided colorectal resection. Methods: A pre-planned analysis of the European Society of Coloproctology 2017 audit. Adult patients (> 16 years) who underwent emergency (unplanned, within 24 h of hospital admission) left sided colonic or rectal resection were included. The primary endpoint was the 30-day major complic…

MaleMedical auditTreatment outcomeanastomotic leak030230 surgery0302 clinical medicinePostoperative ComplicationsProspective StudiesMulti centreemergency surgeryProspective cohort studyColectomyMedical AuditProctectomyProctectomy/adverse effectsProspective auditPrimary anastomosisAnastomosis SurgicalGastroenterologyMiddle Agedsurgical complicationsEuropeTreatment Outcomecolon canceranastomotic leak; colon cancer; emergency surgery; gastrointestinal surgery; rectal cancer; Surgery; surgical complications; surgical outcomes; Gastroenterology030220 oncology & carcinogenesisPostoperative Complications/etiologyFemaleColectomy/adverse effectsEmergency Treatment/adverse effectsAdultmedicine.medical_specialtyAdolescentsurgical outcomesurgical outcomesLeft sidedNO03 medical and health sciencesYoung Adultsurgical complicationmedicineHumansgastrointestinal surgeryrectal cancerEmergency TreatmentColorectal resectionAgedta3126Anastomosis Surgical/methodsbusiness.industryGeneral surgerySurgical StomasSurgical Stomas/statistics & numerical dataSettore MED/18 - Chirurgia GeneraleMultivariate AnalysisSurgerybusiness
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A cross-sectional, multicentre study of the therapeutic management of multiple sclerosis relapses in Italy.

2013

Despite the existence of therapeutic guidelines, management of multiple sclerosis relapse remains heterogeneous. Optimisation of relapse outcome demands an improved understanding of the neurologist's therapeutic attitude towards relapse management, which is the aim of this study. Neurologists from 13 multiple sclerosis centres completed a questionnaire every time they assessed multiple sclerosis relapses. The questionnaire requested a guided description of the relapse's clinical characteristics and an indication of the prescribed therapy, supported with up to 3 out of 20 suggested reasons. Over 3 months, 368 questionnaires were collected. Median percentage (%) of 21 relapses resulting in a …

MalePediatricsNeurologyCross-sectional studymulti center studyAdrenal Cortex HormoneAdrenal Cortex HormonesRecurrenceSurveys and QuestionnairesMultiple SclerosiCorticosteroidSurveys and QuestionnaireRelapseSurveyNeuroradiologyGeneral MedicineMiddle AgedManagementPsychiatry and Mental healthMethylprednisoloneItalyNeurologyPsychiatry and Mental Healthmultiple sclerosiSettore MED/26 - NeurologiaFemaleNeurosurgerymedicine.drugHumanAdultmedicine.medical_specialtyMultiple SclerosisDermatologyMethylprednisolonemedicineHumansMedical prescriptionCross-Sectional Studietherapybusiness.industryMultiple sclerosismedicine.diseaseManagement of multiple sclerosisCross-Sectional StudiesHealth Care SurveyHealth Care SurveysPhysical therapyNeurology (clinical)business2708
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Assessment of systolic left ventricular function: a multi-centre comparison of cineventriculography, cardiac magnetic resonance imaging, unenhanced a…

2005

Aims To assess the agreement of left ventricular ejection fraction (LVEF) determinations from unenhanced echocardiography, contrast-enhanced echocardiography, magnetic resonance imaging (MRI), and cineventriculography as well as the inter-observer agreement for each method. Methods and results In 120 patients, with evenly distributed EF-groups (G 55, 35-55, L 35%), cineventriculography, unenhanced echocardiography with second harmonic imaging, and contrast echocardiography at tow mechanical index with iv administration of SonoVueR were performed. In addition, cardiac MRI at 1.5T using a steady-state free precession sequence was performed in a subset of 55 patients. On-site, and two blinded …

MaleSystolemedia_common.quotation_subjectSecond-harmonic imaging microscopyCoronary DiseaseVentricular Dysfunction LeftPredictive Value of TestsVentriculography First-PassCardiac magnetic resonance imagingmedicineHumansContrast (vision)Multi centreAgedmedia_commonObserver VariationEjection fractionmedicine.diagnostic_testbusiness.industryMagnetic resonance imagingMiddle AgedMagnetic Resonance ImagingEchocardiographyContrast echocardiographyFemaleCardiology and Cardiovascular MedicineNuclear medicinebusinessMechanical indexEuropean Heart Journal
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Ultrastructural changes of the intercellular relationship in impaired human spermatogenesis

1980

In seven hypo- or aspermic patients, electron microscopic investigations of the intercellular connections of the seminiferous tubule were performed. The analysis of cell junctions of Sertoli cells and germ cells revealed irregularities of the Sertoli-cell junctions, hypoplasias of occluding junctions, hypo- and hyperplasias of the Sertoli-spermatid cell junctions and abnormal formation of Sertoli cell junctions with early spermatids, spermatocytes, and spermatogonia. Gap junction-like cell membrane specializations were very rare. Intercellular cytoplasmic bridges of germ cells were always present together with these cells. One hypoplastic bridge connecting two spermatogonia was found. The r…

Maleendocrine systemBiologyCell junctionCell membraneGeneticsmedicineHumansSpermatogenesisCytoskeletonInfertility MaleGenetics (clinical)Blood–testis barrierSertoli CellsTight junctionurogenital systemDesmosomesSeminiferous TubulesSertoli cellSpermatidsSpermatozoaCell biologyMicroscopy ElectronIntercellular Junctionsmedicine.anatomical_structureSeminiferous tubuleSpermatogenesisGerm cellHuman Genetics
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