Search results for "IAC"
showing 10 items of 4189 documents
Daucus carota subsp. maximus (Desf.) Ball from Pantelleria, Sicily (Italy): isolation of essential oils and evaluation of their bioactivity
2021
Daucus is a genus of economically important plants belonging to Apiaceae family spread in temperate regions. Species of this genus are used as food and several biological properties have reported. The chemical composition of the essential oils from different organs (roots, stems and flowers) of Daucus carota subsp. maximus, a species not previously investigated, was analyzed by GC-MS. Our results showed the presence of β-phellandrene as the most abundant component of stems and flowers and of γ-terpinene as a major compound of the oil from the roots. Flower essential oil caused a greater increase in the activity of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX) i…
Chemical composition, antioxidant and anticholinesterase activity of the essential oil of algerian cachrys sicula L
2021
In this work, in order to explore a new Algerian medicinal plant used in traditional medicine, the essential oil of the leaves of Cachrys sicula L. (Apiaceae) collected from Algeria, obtained by hydrodistillation, was analyzed by GC/MS. Thirty-two compounds were identified accounting for 98.6% of the total oil, which is characterized by a high content of monoterpene hydrocarbons (74.8%). The main constituents of the essential oil were β-pinene (17.9%), sabinene (17.8%), myrcene (12%), and α-pinene (11.4%). In vitro antioxidant activity of the essential oil was assayed by three methods, namely ABTS•+, metal chelating, and DPPH• assays. The antioxidant activity of the oil was higher in the AB…
Chemical composition, antimicrobial and antioxidant activity of the essential oils from Pimpinellatragium Vill. subsp. glauca (C. Presl.) C. BrulloBr…
2013
The essential oils from flowers, leaves and stems hydrodistilled from Pimpinella tragium Vill, subsp. glauca were characterised by GC and gas chromatography-mass spectrometry analysis. The C-12 nor-sesquiterpenes are the principal class of metabolites (56.6-70.6%) among which geijerene (28.9÷49.3%) and pregeijerene (10÷19.1%) predominate. Antimicrobial and antioxidant activities were evaluated. The minimum inhibitory concentration values indicate that oil obtained from the stems is the most active for antimicrobial activities and the sample with the biggest antioxidant capacity is the flower oil.
Antimicrobial and antiproliferative activity of Athamanta sicula L. (Apiaceae).
2010
Background: Athamanta sicula L., a member of Apiaceae, is an annual perennial herb and it is known in Sicilian popular medicine with the name of “spaccapietre” (rock splitters), because fresh roots infusions are indicated as diuretic and used in the treatment of diseases of the urinary tract, and to dissolve kidney stones. Materials and Methods: Acetone extracts of leaves, flowers, and stems of A. sicula L. were investigated in vitro for antibacterial and cytotoxic activities. Antimicrobial activity was carried out against bacterial and fungal strains and antiproliferative activity against a group of human cancer cell lines (K-562, NCI-H460, and MCF-7). Results: All acetone extracts, apiol …
Phytochemical investigation and antitumor activity of coumarins from Sicilian accession of Ferulago nodosa (L.) Boiss. roots
2023
Ferulago nodosa (L.) Boiss. (Apiaceae) is a species occurring in the Balkan-Tyrrhenian area being present in Crete, Greece, Albania, and probably in Macedonia. From the roots of this accession of species, not previously investigated, four coumarins, grandivittin, aegelinol benzoate, felamidin and aegelinol, and two terpenoids, (2E)-3-methyl-4-[(3-methyl-1-oxo-2-buten-1yl)oxy]-2-butenoic acid and pressafonin-A, were isolated and spectroscopically characterized. The last one was never detected in Ferulago species. The evaluation of the anti-tumor effects of F. nodosa coumarins on colon cancer HCT116 cells showed only a modest effect on reduction of tumor cell viability. For aegelinol, the red…
Chimney and Periscope Grafts Observed Over 2 Years After Their Use to Revascularize 169 Renovisceral Branches in 77 Patients With Complex Aortic Aneu…
2013
Purpose: To evaluate the performance of periscope and/or chimney grafts (CPGs) in the endovascular treatment of pararenal or thoracoabdominal aneurysms using off-the-shelf devices. Methods: Between February 2002 and August 2012, 77 consecutive patients (62 men; mean age 7369 years) suffering from pararenal aortic (n¼55), thoracoabdominal (n¼16), or arch to visceral artery aneurysms (n¼6) were treated with aortic stent-graft implantation requiring chimney and/or periscope grafts to maintain side branch perfusion. CPGs were planned in advance and were not used as bailout. A standardized follow-up protocol including computed tomographic angiography, laboratory testing, and clinical examination…
A clampless and sutureless aortic anastomosis technique using an endograft connector for aortoiliac occlusive disease in which the aorta cannot be cl…
2012
Bypass surgery in aortoiliac or aortofemoral occlusive disease can be technically demanding and hazardous due to huge calcifications and/or patient co-morbidities. We report about mid-term results of a telescoping sutureless aortic anastomosis technique using endografts as connectors to address such challenging situations. This is a single-center experience (2004–2011) in seven patients (63 ± 6 years) requiring aortoiliac (three) or aortofemoral (four) bypass surgery. In six cases, an aortic stent graft was telescoped into the infrarenal aorta and partly deployed within the aorta and partly outside the aorta. In the first case, a bifurcated stent graft was deployed and the iliac legs were p…
Alteraciones en la producción y secreción de los péptidos natriuréticos y sus moléculas relacionadas en pacientes con insuficiencia cardiaca. Relació…
2016
La insuficiencia cardiaca es un síndrome multifactorial de gran impacto en la asistencia sanitaria debido al aumento de la morbilidad y la mortalidad y la ausencia de un tratamiento curativo. Es el resultado, no solo de una sobrecarga o daño cardiaco, sino también de una compleja interacción de cambios genéticos, neurohormonales, inflamatorios y bioquímicos que actúan sobre el miocito y/o el intersticio. Como consecuencia de estas alteraciones, el paciente con insuficiencia cardiaca tiene niveles anómalos de diversas moléculas (enzimas, hormonas, citocinas…) que son utilizadas como biomarcadores de gran importancia clínica. En este sentido, el papel de los péptidos natriuréticos en la clíni…
Crianza, prosocialidad y relaciones entre los pares en la adolescencia. Factores implicados en los comportamientos antisociales
2017
La adolescencia es la etapa evolutiva de transición entre la infancia y la edad adulta. Este periodo está acompañado de numerosas transformaciones fisiológicas, cognitivas y sociales, que amplían la capacidad de analizar y comprender procesos más complejos, así como las necesidades de ampliar las relaciones sociales. Desde la perspectiva de la Teoría Social Cognitiva y la Psicología Positiva conviene poner el acento en factores personales que estimulan la adaptación social. Con todo, en esta etapa, el adolescente se enfrenta a conflictos personales y sociales, fruto de las nuevas demandas y necesidades (Marina, Rodríguez y Lorente, 2015; Oliva et al., 2010; Viejo y Ortega-Ruiz, 2015). Será …
Bronhiālās astmas ārstēšanai izmantojamo medikamentu aprite "Benu aptiekā 2" 2015. gadā
2016
Astma ir izplatīta hroniska elpceļu iekaisuma slimība, kas skar gan bērnus, gan pieaugušos. To raksturo mainīgi un atkārtoti simptomi, atgriezeniska elpceļu obstrukcija un bronhu spazmas. Astmas ārstēšanas mērķis ir iegūt klīnisko kontroli un samazināt nākotnes risku pacientam. Šī darba mērķis ir izpētīt bronhiālās astmas ārstēšanai izmantojamo medikamentu apriti Benu aptiekā 2 Rīgā 2015. gadā un to atbilstību Global Initiative for Asthma (GINA) 2016. gada vadlīnijām. Astmas terapijā ārsti visbiežāk izraksta astmas kontrolējošos medikamentus. Pieprasītākais astmu kontrolējošais medikaments ir inhalējama glikokortikoīda un ilgstošas darbības β2 agonista kombinētais medikaments flutikazons/ s…