Search results for "IAC"
showing 10 items of 4189 documents
Why does the APA recommend the use of serif fonts?
2013
Antecedentes: las normas de publicación de la American Psychological Association recomiendan el uso de un tipo de letra con serif en los manuscritos (Times New Roman). Sin embargo, no parece haber ninguna razón bien sustentada por la que las fuentes con serif produzcan ventaja alguna durante la lectura de palabras. Método: para examinar el papel de los serifs se realizó un experimento en el que se presentaron frases bien con una fuente serif o sansserif de la misma familia, mientras se registraban los movimientos oculares de los participantes. Resultados: los resultados no revelaron diferencias debidas al tipo de letra en los movimientos oculares, a excepción de un efecto mínimo en el númer…
Análsis del grado de implantación de la conciliación de la vida familiar, personal y profesional en la empresa española: Antecedentes y Resultados
2016
RESUMEN. La presente Tesis Doctoral tiene como objetivos generales, por una parte, indagar y profundizar en el conocimiento acerca de los antecedentes que explican el grado de implantación y uso de las políticas de conciliación VFPP en las pymes españolas, y por otra, establecer los resultados que se derivan de su aplicación. Se trata de un tema de creciente interés para la Academia y objeto de recientes investigaciones en el ámbito particular de la comunidad académica española. En esta investigación se ha estudiado el papel que cumple, bien como barrera, bien como facilitador, la actitud de los directivos ante la implantación y uso de este tipo de políticas; la influencia positiva o negati…
Las barreras del asociacionismo municipal en Colombia: un Análisis Cualitativo Comparativo (QCA)
2019
espanolEn este articulo se identifican algunas de las causas que revelan los bajos niveles de asociacionismo municipal que presentan los departamentos de Colombia. Mediante la aplicacion de un analisis cualitativo comparativo (QCA, por la sigla en ingles de qualitative comparative analysis), se presentan distintas configuraciones causales que explican este fenomeno, tomando como base los datos del Departamento Nacional de Planeacion de Colombia. La variable resultadose ha calculado mediante la proporcion de municipios de cada departamento que pertenecen a algun tipo de asociacion, tomando como referencia los esquemas de asociacion territorial. Entre las conclu-siones que se desprenden, dest…
Expanded CCUG repeat RNA expression in Drosophila heart and muscle trigger Myotonic Dystrophy type 1-like phenotypes and activate autophagocytosis ge…
2016
AbstractMyotonic dystrophies (DM1–2) are neuromuscular genetic disorders caused by the pathological expansion of untranslated microsatellites. DM1 and DM2, are caused by expanded CTG repeats in the 3′UTR of the DMPK gene and CCTG repeats in the first intron of the CNBP gene, respectively. Mutant RNAs containing expanded repeats are retained in the cell nucleus, where they sequester nuclear factors and cause alterations in RNA metabolism. However, for unknown reasons, DM1 is more severe than DM2. To study the differences and similarities in the pathogenesis of DM1 and DM2, we generated model flies by expressing pure expanded CUG ([250]×) or CCUG ([1100]×) repeats, respectively, and compared …
Bacteria-specific cytotoxic CD8+ T cells: a missing link in the pathogenesis of the HLA-B27-associated spondylarthropathies.
1994
The term seronegative spondylarthropathies is used for an entity of rheumatic syndromes of peripheral joints and the spine (ankylosing spondylitis, reactive arthritis, Reiter's syndrome, arthritis in psoriasis and in inflammatory bowel disease) which are strongly associated with the MHC class I molecule HLA-B27. However, the mechanisms whereby HLA-B27 confers disease susceptibility have so far remained unknown. There is strong evidence that gut inflammation and infection with gram-negative bacteria play a role in the induction of B27-associated disease. HLA-B27, like other MHC class I molecules, physiologically binds antigenic peptides in its binding groove and presents them to CD8+ T lymph…
Enterobacterial Antigens with Tropism for Joint Structures and HLA-B27=Restricted Cytotoxic T-Cells in Reactive Arthritis
1995
In reactive arthritis (ReA), sterile synovitis is an immunological sequela following gastrointestinal or urogenital infection with facultatively intracellular bacteria (Yersinia, Salmonella, Shigella, Chlamydia). It is widely accepted now that the development of arthritis is closely related to the persistance of bacteria or bacterial antigens in extraarticular mucosal or lymphoid tissues (i.e. gut mucosa, gut associated lymphoid tissue, genitourinary mucosa); however, it is still unclear which host mechanisms are responsible for the poorer elimination of arthritis-causing microorganisms in those ReA patients. Bacterial components are also camed to the joints where they can be demonstrated i…
High frequency of lumbar fusion in patients denied surgical treatment of the sacroiliac joint.
2019
Purpose: Effective treatment of medical conditions relies on proper diagnosis. Clinical trials show the safety and effectiveness of sacroiliac joint (SIJ) fusion in patients with chronic SI joint dysfunction. To what extent is the condition under recognised? Objective: To determine whether under recognition of SIJ pain affects healthcare trajectories in Spanish patients with low back pain. Methods: Retrospective study of characteristics and consequences of 189 patients with persistent SIJ pain seen in an outpatient neurosurgery clinic. Results: Patients with SIJ pain who were denied surgical treatment had a longer pain duration, higher likelihood of prior lumbar fusion, and a high rate (63%…
Iliosacral Screw Osteosynthesis
2017
Fragility fractures of the anterior pelvic ring are very often combined with fractures of the posterior pelvic ring. The large majority of the posterior fractures is situated in the sacral ala. Non-operative therapy may be cumbersome in patients with a combination of an anterior with a posterior pelvic ring fracture. Any surgical therapy should be as less invasive as possible. Iliosacral screw fixation is a minimal invasive technique. Variations of the upper sacral anatomy make optimal iliosacral screw placement challenging. The vestibule or isthmus is the narrowest part of the bony corridor from the lateral ilium to the S1 sacral body. It always points towards anterior and superior. The wh…
CRT-724 Can the Aortic Wall Communicate with Us?
2014
Association between aortic aneurysm wall and risk of rupture or dissection. Aortic specimens were obtained from 73 patients (51 men and 22 women, whose median age 61.7± 10.7 years) undergoing surgical repair of thoracic ascending aneurysm (TAA). Histopathological and immunohistochemical analyses
Simultaneous worlds. A museum six kilometres long: its roof is the sky; its walls are the town
2016
The scientific committee of the “OC Summer School” inviting the participants to design a spread museum of agriculture in Piacenza, between urban and rural areas, provided an opportunity to reasoning about some dichotomies. Hence, in this text, the project processed in the three weeks of the workshop more than a solution will be consider as a spark that feed a narration between some simultaneous cultural worlds of the architecture: town and museum, inside and outside, private and public, rural and urban.