Search results for "IAD"
showing 10 items of 711 documents
El alma nunca piensa sin fantasmas. Sobre el concepto de psique en Castoriadis
2012
La antropología filosófica de Castoriadis postula la imaginación como facultad productora de sentido, más radical que la propia racionalidad, y considera indisociables lo psíquico y lo social-histórico. Se trata de una filosofía de la praxis, que aspira al desarrollo de una subjetividad reflexiva y deliberante. Combina para ello aportaciones del psicoanálisis con la reflexión filosófica en torno al problema del sentido y el proyecto de autonomía. Sin embargo, la tradición filosófica no ha considerado la importancia de la imaginación tanto en la constitución autónoma del sujeto como de las sociedades. La autonomía (psicológica y social) debe estar vinculada a las posibilidades de ruptura de …
Volcanic CO2 tracks the incubation period of basaltic paroxysms
2021
Description
Non-Innocent Base Properties of 3- and 4-Pyridyl-dithia- and Diselenadiazolyl Radicals : The Effect of N-Methylation
2018
International audience; Condensation of persilylated nicotinimideamide and isonicotinimideamide with sulfur monochloride affords double salts of the 3-, 4-pyridyl-substituted 1,2,3,5-dithiadiazolylium DTDA cations of the general formula [3-, 4-pyDTDA][Cl][HCl] in which the pyridyl nitrogen serves as a noninnocent base. Reduction of these salts with triphenylantimony followed by deprotonation of the intermediate-protonated radical affords the free base radicals [3-, 4-pyDTDA], the crystal structures of which, along with those of their diselenadiazolyl analogues [3-, 4-pyDSDA], have been characterized by powder or single-crystal X-ray diffraction. The crystal structures consist of “pancake” π…
Krytyka wybranych aspektów chrystologii świadków Jehowy w świetle książki Josepfa Ratzingera: Jezus z Nazaretu, cz. I: Od chrztu w Jordanie do Przemi…
2018
Pytanie Chrystusa zawarte we wszystkich ewangeliach synoptycznych: za kogo uważają Go ludzie i kim On jest dla apostołów, wydaje się być wciąż aktualne. Papież Benedykt XVI określa je jako „kamień milowy na drodze Jezusa”. Mimo rozwoju nauk humanistycznych, odpowiedzi jest wiele, a często są one sprzeczne. Niniejsza praca stanowi próbę krytyki wybranych elementów chrystologii świadków Jehowy w świetle obrazu Chrystusa ujętego w książce Josepha Ratzingera Jezus z Nazaretu, cz. I: Od chrztu w Jordanie do Przemienienia. Powyższe zestawienie wykazało, jak liczne i poważne są rozbieżności w postrzeganiu Jezusa przez organizację oraz Jego przedstawieniu w Biblii. Fakty te przemawiają za konieczno…
GSK-3? Can Regulate the Sensitivity of MIA-PaCa-2 Pancreatic and MCF-7 Breast Cancer Cells to Chemotherapeutic Drugs, Targeted Therapeutics and Nutra…
2021
Glycogen synthase kinase-3 (GSK-3) is a regulator of signaling pathways. KRas is frequently mutated in pancreatic cancers. The growth of certain pancreatic cancers is KRas-dependent and can be suppressed by GSK-3 inhibitors, documenting a link between KRas and GSK-3. To further elucidate the roles of GSK-3β in drug-resistance, we transfected KRas-dependent MIA-PaCa-2 pancreatic cells with wild-type (WT) and kinase-dead (KD) forms of GSK-3β. Transfection of MIA-PaCa-2 cells with WT-GSK-3β increased their resistance to various chemotherapeutic drugs and certain small molecule inhibitors. Transfection of cells with KD-GSK-3β often increased therapeutic sensitivity. An exception was observed wi…
Formation of Pyrazol-1,3,4-Thiadiazoles through 1,3-Dipolar Cycloadditions of 3-Thioxo-[1,2,4]-Triazepin-5-one with Nitrilimines: An Experimental and…
2009
In this work the results of experimental and computational study of the title compounds and some ancillary compounds are reported. Two bicyclic pyrazol-1,3,4-thiadiazole derivatives were synthesized by reaction between 6-dimethylaminomethylene-3-thioxo-[1,2,4]- triazepin-5-one 1 and several nitrilimines 2a-f to give corresponding spirocycloadducts 3a-f, which undergo a rapid rearrangement leading to the new bicyclic compounds, 4a-f and 5a-f. These obtained bicyclic products were characterized by 1H and 13C NMR spectroscopy and finally by X-ray crystallography. Theoretical calculations have been carried out using DFT methods to rationalize the formation of the two new bicyclic compounds. Two…
Origin of potassic postcollisional volcanic rocks in young, shallow, blueschist-rich lithosphere
2020
Unusually high Th/La in K-rich orogenic rocks may indicate shallow blueschist-rich sources in accretionary settings.