Search results for "IAPs"
showing 7 items of 7 documents
Bone histology, microanatomy, and growth of the nothosauroid Simosaurus gaillardoti (Sauropterygia) from the Upper Muschelkalk of southern Germany/Ba…
2016
Abstract Simosaurus gaillardoti was a large eosauropterygian (Sauropterygia), a group of diverse diapsid marine reptiles. Its occurrence correlates to transgression phases in the Germanic Basin and a former morphological study hypothesized that Simosaurus was capable of sustained swimming. Microanatomical analysis of five long bones revealed functional differences between the humerus and femur but did not confirm sustained swimming in Simosaurus. It had certain active swimming abilities but – based on microanatomy – it was a less efficient swimmer when compared to contemporaneously living nothosaurs. Simosaurus grew with well-vascularized coarse parallel-fibred bone tissue. Growth marks app…
A procynosuchid cynodont from central Europe
1988
Diversified assemblages of non-mammalian synapsids (or mammal-like reptiles) have long been known from the Upper Permian of southern Africa1 and the Russian Platform2. In contrast, Upper Permian deposits in central and western Europe have rarely yielded remains of terrestrial vertebrates. The German Kupferschiefer (basal Zechstein 1) and its English equivalent, the Marl Slate, have yielded several reptiles: the gliding diapsid Coelurosauravus3 (also known from the Lower Sakamena Formation of Madagascar3−4), the archosauromorph Protorosaurus5, and the pareiasaur Parasaurus6. The Cuttie's Hillock Sandstone of northern Scotland has yielded the pareiasaur Elginia and two dicynodont synapsids an…
The Inhibitor of Apoptosis (IAPs) in Adaptive Response to Cellular Stress.
2012
Cells are constantly exposed to endogenous and exogenous cellular injuries. They cope with stressful stimuli by adapting their metabolism and activating various “guardian molecules.” These pro-survival factors protect essential cell constituents, prevent cell death, and possibly repair cellular damages. The Inhibitor of Apoptosis (IAPs) proteins display both anti-apoptotic and pro-survival properties and their expression can be induced by a variety of cellular stress such as hypoxia, endoplasmic reticular stress and DNA damage. Thus, IAPs can confer tolerance to cellular stress. This review presents the anti-apoptotic and survival functions of IAPs and their role in the adaptive response to…
The marine diapsid reptile Endennasaurus from the Upper Triassic of Italy
2005
The marine reptile Endennasaurus from the Upper Triassic Zorzino Limestone of northern Italy is rede- scribed and reassessed. New details of the skull and postcra- nial skeleton are revealed, confirming the attribution of this genus to the diapsid reptile clade Thalattosauriformes. Phylo- genetic analysis suggests that Endennasaurus was related to the European genus Askeptosaurus and the Chinese Anshun- saurus. Despite a rather conservative postcranial morphology, Endennasaurus clearly occupied a highly specialized dietary niche as it combined a slender tapering premaxillary rostrum with a complete absence of either marginal or palatal teeth.
Vizuālās informācijas ietekme uz sāpju slieksni.
2020
Maģistra darbs ir uzrakstīts angļu valodā uz 36 lapam. Tas satur 17 attēlus, 4 tabulas u 82 atsauces. Mērķis: Izpētīt, kā dažādas tematiskās fotogrāfijas modulē sāpju noteikšanas sliekšņus, un novērtētu emocionālās fotogrāfijas izmantojot pašnovērtējuma manekenu metodi (SAM). Metodes: 21 sievietei sāpju noteikšanas sliekšņi tika izmērīti ar pakāpeniski pieaugoša sprieguma padevi dalībnieku apakšdelmiem. Rezultāti: Sāpju noteikšanas sliekšņi tika samazināti ar negatīvām valences fotogrāfijām (attēlojot vardarbību, dzīvnieku un cilvēku uzbrukumus, zaudējumus). Skatoties neitrālās un pozitīvās fotogrāfijas, sāpju noteikšanas sliekšņi neatšķīrās. SAM pozitīvo fotogrāfiju vērtējumi atklāja augst…
Emotion Elicitation: A Comparison of Pictures and Films
2016
Abstract Pictures and film clips are widely used and accepted stimuli to elicit emotions. Based on theoretical arguments it is often assumed that the emotional effects of films exceed those of pictures, but to date this assumption has not been investigated directly. The aim of the present study was to compare pictures and films in terms of their capacity to induce emotions verified by means of explicit measures. Stimuli were (a) single pictures presented for 6 s, (b) a set of three consecutive pictures with emotionally congruent contents presented for 2 s each, (c) short film clips with a duration of 6 s. A total of 144 participants rated their emotion and arousal states following stimulus …
Regulation of Apoptosis by Inhibitors of Apoptosis (IAPs).
2013
Abstract Inhibitors of Apoptosis (IAPs) are a family of proteins with various biological functions including regulation of innate immunity and inflammation, cell proliferation, cell migration and apoptosis. They are characterized by the presence of at least one N-terminal baculoviral IAP repeat (BIR) domain involved in protein-protein interaction. Most of them also contain a C-terminal RING domain conferring an E3-ubiquitin ligase activity. In drosophila, IAPs are essential to ensure cell survival, preventing the uncontrolled activation of the apoptotic protease caspases. In mammals, IAPs can also regulate apoptosis through controlling caspase activity and caspase-activating platform format…