Search results for "IBA"

No findings of dental defects in children treated with minocycline

2004

Thanks to their broad antimicrobial spectrum, tetracyclines were found to be valuable for the treatment of many infections (10). Unfortunately, they irreversibly bind to calcifying tissues and are deposited along the incremental lines of dentine and enamel, causing defects and staining, from bright yellow to dark brown (3, 5, 8). According to the American Academy of Pediatrics, tetracyclines are not indicated for the treatment of common infections in children younger than 8 years of age. However, doxycycline (a tetracycline analogue) is recommended for treatment of Rocky Mountain spotted fever in children of any age (1). Minocycline has several advantages over other tetracyclines: it is bet…

A recent portrait of bioactive triazoles

2010

Scientists have extensively explored new synthetic routes in order to obtain 1,2,3- and 1,2,4-triazoles as they represent a very interesting class of compounds due to their wide range of biological activities such as antitumor, antiinflammatory, analgesic, antifungal, antibacterial, antiviral, etc. This mini review reports the synthesis and the biological activities of compounds containing a triazole moiety published since 2007. No attempt is made to provide a comprehensive literature overview, our aim is to highlight some more recent examples of synthetic biological active compounds. In particular, we focus on the applications of “click reactions” that allow the regioselective synthesis of…

Lapatiniba protolītisko īpašību izpēte un sāļu iegūšana

2016

Maģistra darba ietvaros veikta lapatiniba potenciometriskā titrēšana neūdens vidē, izmantojot divas šķīdinātāju sistēmas: N,N-dimetilformamīda un ūdens maisījums; metanola, acetonitrila, 1,4 dioksāna un ūdens maisījums. Protonēšanās konstante ūdens vidē noteikta, izmantojot Yasuda Shedlovsky ekstrapolāciju. Veikta lapatiniba sāļu sintēze, izmantojot sālsskābi, p-toluolsulfonskābi, citronskābi, maleīnskābi, vīnskābi, skābeņskābi. Iegūtie produkti analizēti, izmantojot pulvera rentgendifraktometriju, diferenciāli termisko analīzi un kodolmagnētiskās rezonanses spektroskopiju. Atsevišķiem paraugiem pārbaudīta stabilitāte paaugstināta gaisa relatīvā mitruma apstākļos.

5-6 gadīgu bērnu gribas īpašību sekmēšana rokdarbos

2018

Bakalaura darba autore: Laura Jace. Bakalaura darba temats: “5- 6 gadīgu bērnu gribas īpašību sekmēšana rokdarbos” . Mērķis ir pētīt vecākā pirmsskolas vecuma bērnu gribas īpašību veidošanos un sekmēšanas iespējas rokdarbos. Darba teorētiskās literatūras analīzē tika noskaidrots, ka griba ir viena no nozīmīgākajām cilvēka personības īpašībām, kas izpaužas gatavībā mērķtiecīgai, apzinātai darbībai, pārvarot grūtības, un cenšoties sasniegt izvēlēto mērķi. Svarīga loma ir skolotājam, kurš atrodas blakus bērnam, ceļā uz gribas sekmēšanu, motivējot un ieinteresējot darbībai. Pirmsskolas vecumā pedagogs rada bērnā vēlēšanos darboties, radīt un tiekties uz mērķi. Pētnieciskās darbības rezultātā pi…

Modelling biological and chemically induced precipitation of calcium phosphate in enhanced biological phosphorus removal systems

2011

The biologically induced precipitation processes can be important in wastewater treatment, in particular treating raw wastewater with high calcium concentration combined with Enhanced Biological Phosphorus Removal. Currently, there is little information and experience in modelling jointly biological and chemical processes. This paper presents a calcium phosphate precipitation model and its inclusion in the Activated Sludge Model No 2d (ASM2d). The proposed precipitation model considers that aqueous phase reactions quickly achieve the chemical equilibrium and that aqueous-solid change is kinetically governed. The model was calibrated using data from four experiments in a Sequencing Batch Rea…

A new approach to predict the fish fillet shelf-life in presence of natural preservative agents

2017

Three data sets concerning the behaviour of spoilage flora of fillets treated with natural preservative substances (NPS) were used to construct a new kind of mathematical predictive model. This model, unlike other ones, allows expressing the antibacterial effect of the NPS separately from the prediction of the growth rate. This approach, based on the introduction of a parameter into the predictive primary model, produced a good fitting of observed data and allowed characterising quantitatively the increase of shelf-life of fillets.

Evaluation of Changes in Gut Microbiota in Patients with Crohn’s Disease after Anti-Tnfα Treatment: Prospective Multicenter Observational Study

2020

Background: Crohn’s disease is believed to result from the interaction between genetic susceptibility, environmental factors and gut microbiota, leading to an aberrant immune response. The objectives of this study are to evaluate the qualitative and quantitative changes in the microbiota of patients with Crohn’s disease after six months of anti-tumor-necrosis factor (anti-TNFα) (infliximab or adalimumab) treatment and to determine whether these changes lead to the recovery of normal microbiota when compared to a control group of healthy subjects. In addition, we will evaluate the potential role of the Faecalibacterium prausnitzii/Escherichia coli and Faecalibacterium prausnitzii/Clostridium…

509 Discovery of plants and fungi with antibacterial activity against Propionibacterium acnes

2016

Sulla domanda di storia del pensiero economico. Alcune evidenze, alcune riflessioni

2020

In questo saggio si presenta un panorama dello stato attuale e del possibile futuro della Storia del Pensiero Economico (SPE). Nella prima parte ci concentriamo sulla domanda di SPE proveniente dall’interno del mondo accademico, da settori disciplinari diversi, a livello mondiale. La seconda parte invece individua alcuni ambiti esterni alla nostra professione che manifestano interesse nei confronti della SPE. Nella terza parte proviamo infine a proiettarci nel futuro, segnalando alcuni percorsi che ci sembra potrebbero andare incontro alle richieste identificate In this chapter we offer a presentation of the current state and possible evolution of studies in the History of Economic Thought.…

Prostituzione. Aporie e tabù di un nuovo diritto penale tutorio

2018

Molteplici sono le forme attraverso le quali la prostituzione può essere esercitata e plurimi sono i suoi modelli normativi di regolamentazione: tradizionalmente, si contendono il campo il proibizionismo, il regolamentarismo e l’abolizionismo; più di recente la c.d. decriminalizzazione e il c.d. neo-proibizionismo. In questo volume, dopo una breve disamina delle possibili forme e dei plurimi significati della prostituzione, ci si sofferma preliminarmente su alcuni ordinamenti-tipo che presentano caratteristiche peculiari ora dell’uno ora dell’altro dei modelli normativi attuabili, tenendo conto anche di recenti e significative sentenze di talune Corti supreme in ordinamenti di tipo abolizio…