Search results for "ICAD"
showing 10 items of 1297 documents
The Human Biodiversity in the Middle of the Mediterranean. Study of native and settlers populations on the Sicilian context
2020
[IT] Negli ultimi 200.000 anni, la specie umana si è diffusa in tutta la Terra, adattando la sua morfologia e fisiologia a un'ampia gamma di habitat. Lo scheletro umano ha quindi registrato i principali effetti ambientali e di conseguenza i reperti scheletrici assumono grande importanza nell'indagine dei processi evolutivi. Oggi le moderne tecniche di indagini quantitative delle principali caratteristiche morfologiche consentono di metterle in relazione con la variabilità genetica. La posizione geografica della Sicilia, l'isolamento e la sua lunga e dinamica storia di colonizzazione (diversi e numerosi contributi culturali e biologici) hanno creato un contesto peculiare che consente uno stu…
La sostenibilidad turística a través de un índice sintético amparado en los 17 ODS. Los casos de Canet d'En Berenguer, Cullera y Oliva
2022
La sostenibilidad alcanzó un significativo interés en el sector turístico a partir de la Cumbre de la Tierra (Río, 1992). Desde entonces se ha hecho necesario medir sus variables, por lo que distintas instituciones vienen desarrollando sistemas de indicadores turísticos, aunque, en su mayoría, no tienen en cuenta las características o la idiosincrasia local. El generalizar los indicadores para todos los territorios desatiende y equipara problemas de carácter ambiental, social, político y económico, obviando la singularidad del destino. Por otro lado, varios estudios recientes certifican empíricamente que factores como las masificaciones y el calentamiento global, consecuencia de la falta de…
LungBEAM: A prospective multicenter study to monitor stage IV NSCLC patients with EGFR mutations using BEAMing technology
2021
Abstract Objectives The aim of LungBEAM was to determine the value of a novel epidermal growth factor receptor (EGFR) mutation test in blood based on BEAMing technology to predict disease progression in advanced non‐small cell lung cancer (NSCLC) patients treated with first‐ or second‐generation EGFR‐tyrosine kinase inhibitors (EGFR‐TKIs). Another goal was to monitor the dynamics of EGFR mutations, as well as to track EGFR exon 20 p.T790M (p.T790M) resistance during treatment, as critical indicators of therapeutic efficacy and patient survival. Methods Stage IV NSCLC patients with locally confirmed EGFR‐TKI sensitizing mutations (ex19del and/or L858R) in biopsy tissue who were candidates to…
Prognostic heterogeneity of adult B-cell precursor acute lymphoblastic leukaemia patients with t(1;19)(q23;p13)/TCF3-PBX1 treated with measurable res…
2021
Programa para el Tratamiento de Hemopatias Malignas (PETHEMA) Group (Spanish Society of Hematology, SEHH).
Measurement of continuous improvement in the safety of oncologic patients
2013
Objetivo: Analizar la mejora continua en la seguridad del paciente oncológico, a través de la evolución de los indicadores de calidad establecidos tras la implantación de un sistema de gestión de la calidad (SGC) según norma ISO 9001:2008, en una unidad de oncología farmacéutica (UOF). Método: Estudio observacional prospectivo realizado entre Enero 2008 y Diciembre de 2011. La certificación ISO 90012008 de la UOF incluyó los procesos de prescripción electrónica, validación, preparación, dispensación y administración del tratamiento antineoplásico. Se establecieron los indicadores de calidad: errores de medicación (EM) de preparación y dispensación que no alcanzan al paciente, y EM que alcan…
Deciphering Multiple Sclerosis Progression
2021
Esclerosi múltiple; Neurodegeneració Esclerosis múltiple; Neurodegeneración Multiple sclerosis; Nneurodegeneration Multiple sclerosis (MS) is primarily an inflammatory and degenerative disease of the central nervous system, triggered by unknown environmental factors in patients with predisposing genetic risk profiles. The prevention of neurological disability is one of the essential goals to be achieved in a patient with MS. However, the pathogenic mechanisms driving the progressive phase of the disease remain unknown. It was described that the pathophysiological mechanisms associated with disease progression are present from disease onset. In daily practice, there is a lack of clinical, ra…
The potential of serum neurofilament as biomarker for multiple sclerosis
2021
Abstract Multiple sclerosis is a highly heterogeneous disease, and the detection of neuroaxonal damage as well as its quantification is a critical step for patients. Blood-based serum neurofilament light chain (sNfL) is currently under close investigation as an easily accessible biomarker of prognosis and treatment response in patients with multiple sclerosis. There is abundant evidence that sNfL levels reflect ongoing inflammatory-driven neuroaxonal damage (e.g. relapses or MRI disease activity) and that sNfL levels predict disease activity over the next few years. In contrast, the association of sNfL with long-term clinical outcomes or its ability to reflect slow, diffuse neurodegenerativ…
Multi‐criteria decision‐making approach for modular enterprise resource planning sorting problems
2021
[EN] Implementing Enterprise Resource Planning (ERP) systems is currently recognized as a best practice with wide associated possibilities of business improvement for companies. Integrating these kinds of systems with business processes in the most efficient way requires to endeavour as much as possible simplifications for final users, which can be pursued by optimizing crucial software characteristics. The present article proposes a novel Multi-Criteria Decision-Making (MCDM) approach to deal with such an issue. Specifically, the ELECTRE (ELimination Et Choix Traduisant la REalite) TRI technique is suggested to assign ERP modules into predefined and ordered categories according to maintain…
On the importance of perspective and flexibility for efficiency measurement: effects on the ranking of decision-making units
2017
[EN] The efficiency of a firm can be assessed from several perspectives and using a variety of methodologies. Data envelopment analysis (DEA) is one of the most commonly used methodologies. Conventional DEA analyses or models allow one to classify decision-making units (DMUs) into efficient and inefficient ones based on their efficiency scores, which could also be used for ranking DMUs; however, such rankings generally show many ties. Super-efficiency DEA analyses have been proposed to address the tie issue. On the other hand, conventional DEA analyses only take account of a single perspective in estimating efficiency scores. Cross-efficiency DEA analyses provide an alternative that takes a…
Advanced Optical Processing of Microwave Signals
2005
The authors present a review on the recent approaches proposed to implement transversal RF filters. Different tunable transversal filters consisting of wavelength tunable optical taps and those employing the tunability of dispersive devices are presented showing their high-performance characteristics. A comprehensive review of the fundamentals and a discussion on the main limitation of these structures are also included.