Search results for "ICF"

Prismatic Adaptation as a Novel Tool to Directionally Modulate Motor Cortex Excitability: Evidence From Paired-pulse TMS

2014

Abstract Background The prismatic adaptation (PA) is a visuo-motor procedure that has captured the attention of neuroscientists in the last decades, hence it seems to affect high-order cognition. However, the basic neural processes related to PA and its effects on cortical plasticity are not clear yet. Objective/hypothesis The aim of the present study is to explore whether PA induces a direct effect on the motor cortices (M1) excitability. Methods Fourteen healthy participants were submitted to paired-pulse TMS to measure short-intracortical-inhibition (SICI) and intracortical-facilitation (ICF) on both the left and the right M1, before and after PA, that could induce a leftward or rightwar…

High-Frequency Transcranial Magnetic Stimulation on Motor Cortex of Patients Affected by Migraine With Aura: A Way to Restore Normal Cortical Excitab…

2009

We showed reduced motor intracortical inhibition (ICI) and paradoxical increase of intracortical facilitation (ICF) to 1 Hz repetitive transcranial magnetic stimulation (rTMS) in patients affected by migraine with aura (MA). In conditions of enhanced excitability due to a reduced inhibition, high-frequency rTMS was found to potentiate intracortical inhibition. Here we explored the conditioning effects of high-frequency priming stimulation of motor cortex with the aim of normalizing excitability reverting paradoxical facilitation by 1 Hz rTMS in MA. Nine patients with MA and nine healthy controls underwent a paired-pulse TMS paradigm to evaluate motor intracortical excitability (ICI and ICF…

A scoping review on interventions to promote physical activity among adults with disabilities

2016

People with disabilities are at increased risk for obesity as well as other secondary conditions that lead to further decline in health and functional status. Despite there being strong evidence that physical activity (PA) can help to reduce the incidence and severity of preventable conditions, approximately half of all adults with disabilities get no regular physical activity. In addition, there is limited knowledge on the PA promotion interventions effectiveness among individuals with disabilities. Recently the Behaviour Change Techniques Taxonomy version 1 (BCT Taxonomy v1) became available as a method for reporting, replicating, and synthesizing research evidence, yet it is lacking in s…

MS-tautia sairastavien selviytyminen ADL-toiminnoista kahden vuoden seurannan aikana ICF-luokituksen itsestä huolehtimisen ja liikkumisen osa-alueill…

2006

EK-asteikon soveltuvuus Duchennen lihasdystrofiaa sairastavien toimintakyvyn kuvaamiseen ICF-luokituksen mukaan

2005

Losing DNA methylation at repetitive elements and breaking bad

2021

Abstract Background DNA methylation is an epigenetic chromatin mark that allows heterochromatin formation and gene silencing. It has a fundamental role in preserving genome stability (including chromosome stability) by controlling both gene expression and chromatin structure. Therefore, the onset of an incorrect pattern of DNA methylation is potentially dangerous for the cells. This is particularly important with respect to repetitive elements, which constitute the third of the human genome. Main body Repetitive sequences are involved in several cell processes, however, due to their intrinsic nature, they can be a source of genome instability. Thus, most repetitive elements are usually meth…

The activities and participation categories of the ICF Core Sets for multiple sclerosis from the patient perspective.

2013

Purpose: To validate the activities and participation components of The International Classification of Functioning, Disability and Health (ICF). Methods: In this cross-sectional study, 113 Finnish community-dwelling persons with MS were assessed using a semi-structured interview provided by the Canadian Occupational Performance Measure (COPM) to capture participants’ self-perceived problems in everyday activities and participation. Problems were linked to the ICF categories. Results: Participants identified 527 of the most important occupational performance problems. They covered all chapters of the ICF Activities and Participation components. Forty-one categories out of a total 53 ICF act…

Disability assessment in an Italian cohort of patients with obesity using an International Classification of Functioning, Disability and Health (ICF)…

2020

Background Obesity is a clinical condition that contributes to the development of related disability in different areas (physical, psychological and social). Multidisciplinary treatment calls for specific instruments able to evaluate all related functional problems. We have developed a tool (an ICF-based assessment instrument, the ICF-OB schedule) to evaluate obesity-related disability, composed of an inventory of 71-items from the WHO International Classification of Functioning, Disability and Health (ICF). Aim The aim of the present study was to validate this new tool for the definition of obesity-related disability. We also sought to examine the relationship between obesity disability, a…

Organized Sport Participation and Physical Activity Levels among Adolescents with Functional Limitations

2017

Sufficient and regular physical activity is considered a protective factor, reducing the onset of secondary disability conditions in adolescents with chronic diseases and functional limitations. The aim of this study was to explore whether participation in organized sport may be associated to higher levels of physical activity in adolescents with functional limitations, based on a national representative sample. Data from the Health Behaviour in School-aged Children (HBSC) study collected in Finland from two data collection rounds (2002 and 2010) were conducted and pooled from adolescents aged between 13 and 15 years old with functional limitations (n = 1041). Differences in self-reported p…

Physical activity of adolescents with long term illnesses or disabilities in reference to ICF personal factors

2016

Participation and activities are important for adolescents’ functioning and health. This is in line with the World Health Organisation’s International Classification of Functioning, Disability and Health (ICF). Main areas of functioning include physical activities (PA) and participation in organised sport clubs. To ensure adolescents with long term illnesses or disabilities (LTID) can participate fully in society, functional abilities interact with contextual environmental and personal factors. Because habits and attitudes of adolescents can carry through to adulthood, it is important to assess the personal factors in relation to activities and participation. Therefore, the aims of this stu…