Search results for "ICSI"
showing 10 items of 27 documents
Assessing infertility-related stress: The factor structure of the Fertility Problem Inventory in Italian couples undergoing infertility treatment
2015
The factor structure of the Fertility Problem Inventory (FPI) and its invariance across gender were examined in Italian couples undergoing infertility treatment. About 1000 subjects (both partners of 500 couples) completed two questionnaires prior to commencing infertility treatment at a private Clinic in Palermo, Italy. Confirmatory Factor Analysis demonstrated that the original factor structure of the FPI was partially confirmed. Two correlated factors (Infertility Life Domains and Importance of Parenthood) were obtained via a post hoc Exploratory Factor Analysis. Finally, the invariance of this factor structure across gender was confirmed. The study supported the relevance of two interre…
Health outcomes of children born after IVF/ICSI: a review of current expert opinion and literature
2014
The Sixth Evian Annual Reproduction (EVAR) Workshop Group Meeting was held to evaluate the impact of IVF/intracytoplasmic sperm injection on the health of assisted-conception children. Epidemiologists, reproductive endocrinologists, embryologists and geneticists presented data from published literature and ongoing research on the incidence of genetic and epigenetic abnormalities and congenital malformations in assisted-conception versus naturally conceived children to reach a consensus on the reasons for potential differences in outcomes between these two groups. IVF-conceived children have lower birthweights and higher peripheral fat, blood pressure and fasting glucose concentrations than …
Preconception genome medicine: current state and future perspectives to improve infertility diagnosis and reproductive and health outcomes based on i…
2021
Abstract BACKGROUND Our genetic code is now readable, writable and hackable. The recent escalation of genome-wide sequencing (GS) applications in population diagnostics will not only enable the assessment of risks of transmitting well-defined monogenic disorders at preconceptional stages (i.e. carrier screening), but also facilitate identification of multifactorial genetic predispositions to sub-lethal pathologies, including those affecting reproductive fitness. Through GS, the acquisition and curation of reproductive-related findings will warrant the expansion of genetic assessment to new areas of genomic prediction of reproductive phenotypes, pharmacogenomics and molecular embryology, fur…
Failures (with some successes) of assisted reproduction and gamete donation programs
2013
Although the possibilities for the treatment of infertility have been improved tremendously, not every couple will be treated successfully.Crude overall pregnancy rates of 50-65% per patient can be achieved nowadays, irrespective of the type of profertility treatment applied first.IVF only accounts for about 20% of the pregnancies achieved. Dropout is an important reason for not reaching the estimated pregnancy rate. Even after failed IVF, spontaneous pregnancies do occur. Sperm and oocyte donation (OD) offer additional chances to subfertile couples. Severity of the male factor (in sperm donation) and young donor age (in OD) are important determinants of success.Analysis of assisted reprodu…
Valor de los estudios cromosómicos en espermatozoides mediante la técnica de hibridación in situ fluorescente (FISH) en parejas estériles
2013
Los varones estériles presentan una frecuencia elevada de anomalías citogenéticas, algunas de ellas detectables mediante el cariotipo, pero otras limitadas a las células germinales como resultado de meiosis anormales. Con las nuevas técnicas de reproducción asistida como la Inyección Intracitoplásmica de Espermatozoides (ICSI), la fecundación por espermatozoides cromosómicamente anormales puede dar lugar a fallos de implantación, abortos de repetición y a la transmisión de anomalías cromosómicas a la descendencia. La hibridación in situ fluorescente (FISH) de espermatozoides es una técnica de análisis citogenético que, mediante el marcado de los cromosomas con moléculas de ADN fluorescentes…
Shock-cloud interaction in the Vela SNR II. Hydrodynamic model
2006
In the framework of the study of the X-ray and optical emission in supernova remnants we focus on an isolated X-ray knot in the northern rim of the Vela SNR (Vela FilD), whose X-ray emission has been studied and discussed in Paper I. We aim at understanding the physical origin of the X-ray and optical emission in FilD, at understanding the role of the different physical processes at work, and at obtaining a key for the interpretation of future X-ray observations of SNRs. To this end we have pursued an accurate ``forward'' modeling of the interaction of the Vela SNR shock with an ISM cloud. We perform hydrodynamic simulations and we directly compare the observables synthesized from the simul…
Effects of work exposure to electromagnetic waves and organic compounds on sperm DNA fragmentation in patients undergoing ICSI
2011
Qualification d’investissement et compétence en arbitrage international relatif aux investissements : la théorie du contrôle séparé devant le CIRDI
2014
La compétence d’un arbitre chargé d’appliquer le droit international des investissements exige l’existence préalable d’un investissement étranger. La présente étude analyse les difficultés du contrôle de l’existence de l’investissement devant le Centre international pour le règlement des différends relatifs aux investissements (CIRDI) et propose des moyens pour les surmonter. L’importance de la Convention de Washington du 18 mars 1965 explique l’attention particulière portée au CIRDI. En tenant compte des diverses approches proposées par la doctrine et la jurisprudence et de leurs fondements, la démarche suggérée par l’auteur est basée sur la dissociation des sources conventionnelles à l’or…
Does Hysteroscopic Dissection of Partial Uterine Septum Represent a Risk Factor for Placental Abnormalities in Subsequent Pregnancy Compared with Con…
2022
Background: Hysteroscopic septum dissection (HSD) is thought to improve fertility and pregnancy outcomes. However, the available literature suggests that uterine surgery can cause placental abnormalities in subsequent pregnancies. Methods: A case–control study was performed at the University Medical Center of Ljubljana, Department of Human Reproduction, from 1 January 2016 to 31 December 2018. The primary outcome was the association between HSD and the occurrence of placental abnormalities. We included women who underwent HSD due to infertility. Age-matched women who underwent hysteroscopic surgery for other issues were considered as controls. In addition, we divided the groups according to…
Importancia del tamaño uterino en el diagnóstico y pronóstico de las mujeres con problemas de fertilidad
2015
1. Título del proyecto: “Importancia del tamaño uterino en el diagnóstico y pronóstico de las mujeres con problemas de fertilidad”. 2. Hipótesis de trabajo: - ¿Es la hipoplasia uterina uno de los factores a valorar en pacientes en estudio de fertilidad? - ¿Cuál es la relación entre el tamaño uterino y un resultado positivo de gestación en un ciclo de una técnica de reproducción asistida? 3. Objetivos: 3.1. Principales: - Valorar el tamaño uterino medido en su diámetro longitudinal definido por la distancia desde orificio cervical externo (OCE) hasta el límite fúndico de la cavidad endometrial: histerometría. Establecer los límites, en centímetros, que se asocien a menores tasas de gestación…