Search results for "IDEATION"
showing 10 items of 60 documents
Efavirenz and the CNS: what we already know and questions that need to be answered
2015
The NNRTI efavirenz has long been one of the most frequently employed antiretroviral drugs in the multidrug regimens used to treat HIV infection, in accordance with its well-demonstrated antiretroviral efficacy and favourable pharmacokinetics. However, growing concern about its adverse effects has sometimes led to efavirenz being replaced by other drugs in the initial treatment selection or to switching of therapy to efavirenz-free regimens in experienced patients. Neurological and neuropsychiatric reactions are the manifestations most frequently experienced by efavirenz-treated patients and range from transitory effects, such as nightmares, dizziness, insomnia, nervousness and lack of conc…
The influence of friendship and communication network density on individual innovative behaviours: a multilevel study
2016
The present study examines whether teams’ friendship and communication network density are related to individual innovative behaviours (IIBs: idea generation, suggestion making, idea promotion and idea implementation). The study sample was composed of 28 teams comprising 101 members. The results obtained by means of multilevel structural equations modelling showed that friendship network density had an indirect positive relationship with the four IIBs through the density of team communication networks.
MENTAL HEALTH AND SUICIDAL IDEATION AMONG 1ST AND 2ND GENERATION MIGRANTS - Results from the Gutenberg Health Study
2016
The association of physical multimorbidity with suicidal ideation and suicide attempts in England: A mediation analysis of influential factors
2022
Background: Suicide is one of the most important causes of deaths in the United Kingdom, and the numbers are currently increasing. Aim: There are numerous identified determinants of suicidality, and physical multimorbidity is potentially important but is currently understudied. Thus, this study aims to investigate the association of physical multimorbidity with suicidality. Methods: Cross-sectional data from the Adult Psychiatric Morbidity Survey 2007, which was conducted in England between October 2006 and December 2007 by the National Center for Social Research and Leicester University were analyzed. Respondents were asked about 20 physical health conditions, and suicidal ideation and sui…
Evidence, and replication thereof, that molecular-genetic and environmental risks for psychosis impact through an affective pathway
2022
AbstractBackgroundThere is evidence that environmental and genetic risk factors for schizophrenia spectrum disorders are transdiagnostic and mediated in part through a generic pathway of affective dysregulation.MethodsWe analysed to what degree the impact of schizophrenia polygenic risk (PRS-SZ) and childhood adversity (CA) on psychosis outcomes was contingent on co-presence of affective dysregulation, defined as significant depressive symptoms, in (i) NEMESIS-2 (n = 6646), a representative general population sample, interviewed four times over nine years and (ii) EUGEI (n = 4068) a sample of patients with schizophrenia spectrum disorder, the siblings of these patients and controls.ResultsT…
Association of extent of cannabis use and psychotic like intoxication experiences in a multi-national sample of first episode psychosis patients and …
2021
AbstractBackgroundFirst episode psychosis (FEP) patients who use cannabis experience more frequent psychotic and euphoric intoxication experiences compared to controls. It is not clear whether this is consequent to patients being more vulnerable to the effects of cannabis use or to their heavier pattern of use. We aimed to determine whether extent of use predicted psychotic-like and euphoric intoxication experiences in patients and controls and whether this differs between groups.MethodsWe analysed data on patients who had ever used cannabis (n = 655) and controls who had ever used cannabis (n = 654) across 15 sites from six countries in the EU-GEI study (2010–2015). We used multiple regres…
InspirationWall
2015
Collaborative idea generation leverages social interactions and knowledge sharing to spark diverse associations and produce creative ideas. Information exploration systems expand the current context by suggesting novel but related concepts. In this paper we introduce InspirationWall, an unobtrusive display that leverages speech recognition and information exploration to enhance an ongoing idea generation session with automatically retrieved concepts that relate to the conversation. We evaluated the system in six idea generation sessions of 20 minutes with small groups of two people. Preliminary results suggest that InspirationWall contrasts the decay of idea productivity over time and can t…
Childhood Maltreatment, Pathological Personality Dimensions, and Suicide Risk in Young Adults
2018
Several studies have demonstrated that child maltreatment (psychological, physical, and sexual abuse, and neglect) may be a significant factor in the development of pathological personality traits that increase the risk for suicidal ideation and behavior from adolescence to adulthood. Currently, the challenge is to understand how different forms of early negative experiences render an individual prone to develop specific personality traits and, in turn, be more vulnerable to suicide risk. To understand the relationship between childhood maltreatment and personality dimensions in suicide risk, our study aims to explore the role of self-criticism and dependency, two different pathological per…
Childhood Maltreatment, Pathological Personality Dimensions, and Suicide Risk in Young Adults
2019
Several studies have demonstrated that child maltreatment (psychological, physical, and sexual abuse, and neglect) may be a significant factor in the development of pathological personality traits that increase the risk for suicidal ideation and behavior from adolescence to adulthood. Currently, the challenge is to understand how different forms of early negative experiences render an individual prone to develop specific personality traits and, in turn, be more vulnerable to suicide risk. To understand the relationship between childhood maltreatment and personality dimensions in suicide risk, our study aims to explore the role of self-criticism and dependency, two different pathological per…
Cyberbullying, psychosocial adjustment and suicide ideation in adolescence
2019
El ciberacoso escolar suscita una creciente preocupacion social en la comunidad cientifica y en la sociedad en general. Las consecuencias del mismo en la victima son muy serias: se han encontrado numerosos indicadores de desajuste social, entre los cuales destaca la ideacion suicida. Desde esta perspectiva, el objetivo principal de este trabajo ha sido analizar las relaciones entre la cibervictimizacion y la ideacion suicida en adolescentes victimas de ciberacoso escolar a traves de las variables de desajuste psicosocial de soledad, sintomatologia depresiva, estres percibido y malestar psicologico. En esta investigacion participaron 1,062 adolescentes (547 chicos y 515 chicas), con un rango…