Search results for "IDENTIFICATION"

Modifying the reactivity of copper (II) by its encapsulation into polydimethylsiloxane: A selective sensor for ephedrine-like compounds

2018

This paper demonstrates that the reactivity of copper (II) can be modified through its entrappment in a polymeric matrix of polydimethylsiloxane (PDMS), which makes possible the reaction into the support instead of in solution. Amino-containing compounds such as amino acids, proteins and sugars, which react with Cu (II) in solution, do not react inside the polymer. As a prove of concept, a highly specific Cu (II) PDMS-based sensor for ephedrines has been developed in this work. When the sensors are put into contact with solutions of these drugs under basic conditions, a change in their color from pale green to purple is observed. This change enables the visual identification of ephedrine (E…

Tailor‐Made Amino Acids and Fluorinated Motifs as Prominent Traits in Modern Pharmaceuticals

2020

Structural analysis of modern pharmaceutical practices allows for the identification of two rapidly growing trends: the introduction of tailor-made amino acids and the exploitation of fluorinated motifs. Curiously, the former represents one of the most ubiquitous classes of naturally occurring compounds, whereas the latter is the most xenobiotic and comprised virtually entirely of man-made derivatives. Herein, 39 selected compounds, featuring both of these traits in the same molecule, are profiled. The total synthesis, source of the corresponding amino acids and fluorinated residues, and medicinal chemistry aspects and biological properties of the molecules are discussed.

Identification of monocyte subpopulations and signaling pathways responsible for the immune response to fungal immunomodulatory glycoprotein AMPD

2016

Erratum to: “Identification of a peptide mimicking the binding pattern of an antiphospholipid antibody”

2006

Chapter 2 Biosynthesis in Rauwolfia serpentina Modern Aspects of an Old Medicinal Plant

1995

Publisher Summary This chapter discusses a research on Rauwolfia , which was achieved after the generation of a cell suspension with extraordinary growth characteristics and physiological behavior. The investigations demonstrated that a range of techniques is now available for the clarification of complete metabolic pathways, provided that the appropriate efficient biological system is available. The isolation and identification of each single enzyme have almost become routine, even if an extremely sensitive protein analytic technique is necessary when several kilograms of fresh plant cells are reduced to a few micrograms of homogenous protein. The successful identification of a total of 20…

Human Leukocyte Antigen Typing Using High-Throughput DNA and RNA Sequencing and Application for Cell Line Identification

2019

Paternity testing of endangered species of birds by DNA fingerprinting and random amplified polymorphic DNA fingerprinting

1994

Since 1985 DNA fingerprinting is the method of choice to solve forensic problems such as paternity testing (Jeffreys et al., 1986) or identification of immigration cases (Jeffreys et al., 1985 a, b). Its applicability became evident not only in man but also in many biological problems. Jeffreys’probes 33.15 and 33.6 or Epplen’s oligonucleotide probes were used in DNA fingerprinting of dogs and cats (Jeffreys & Morton, 1987), non-human primates (Weiss, 1989), birds (Longmire et al., 1991, Miyaki et al., 1993), fishes (Schartl et al., 1993) or even plants (Weising et al., 1991). Especially its application in paternity testing turned to account in many species of animals (Lubjuhn et al., 1991,…

Identification des espèces d'arbres à partir de données T-LiDAR Tree species identification using T-LiDAR data

2013

National audience; En raison de l'utilisation croissante des scanners LiDAR terrestre (T-LiDAR) dans le domaine forestier, le développement d'outils logiciels pour la mesure automatique d'attributs d'inventaire forestier est devenu un domaine de recherche important. De nombreux travaux portant sur la localisation des arbres dans un nuage de points, la mesure du diamètre à hauteur de poitrine (DHP) ou la mesure de la hauteur des arbres ont été décrits dans la littérature. Cependant, le problème de l'identification des espèces d'arbres à partir de données T-LiDAR a été peu abordé. La plupart des travaux utilisent des données LiDAR aéroportées et les espèces des arbres sont déterminées à l'éch…

Copenhagen failure : a rhetorical treatise of how speeches unite and divide mankind

2010

The purpose of this treatise is to analyse five of the Copenhagen Climate Convention's main speeches to see how they supported or weakened the agreement possibilities in the convention. Particular focus will be on the elements that divide or unite negotiators and whether the summit's failing outcome is already built in the pre-planned speeches held at the main podium. Theoretically, the study builds on Kenneth Burke's identification thesis and Elizabeth L. Malone's climate change debate analysis. I combine these in my analysis using a revised version of Malone's argument family classification tool putting it into Burke's theoretical framework. The central concept is Burke's identification, …

Heteroglossic and multimodal resources in use : participation across spaces of identification in a Christian lifestyle sports community

2017

This dissertation examines how members of one particular youth community, Christian lifestyle sports enthusiasts in Finland, use language and other semiotic resources to construct participation in their community of practice (CoP). The CoP is organized around the late-modern activity culture of lifestyle sports. The participants also share the Christian faith and in their snowboarding camps organize Bible study sessions and engage in prayer and worship. The theoretical and methodological framework incorporates sociolinguistics, social semiotics, discourse studies and connective ethnography, including the exploration of both the digital and physical spaces of the community. The dissertation …