Search results for "IEP"
showing 10 items of 321 documents
CCDC 907670: Experimental Crystal Structure Determination
2013
Related Article: Jochen Körber, Stefan Löffler, Dieter Schollmeyer, Udo Nubbemeyer|2013|Synthesis|45|2875|doi:10.1055/s-0033-1338519
Nutrient Assimilation by First-Feeding African Catfish, Clarias gariepinus , Assessed Using Stable Isotope Analysis
2013
Knowledge of ingredients assimilation and biomass contribution to recipient fish is important in feed formulation. The stable isotopes of 13C and 15N were used to investigate the assimilation and biomass contribution of bambaranut, Voandzeia subterranea, meal (BNM), corn, Zea mays, meal (CM) and fish meal (FM), in FM substituted diets of first feeding African catfish, Clarias gariepinus, during a 30-d experiment. The catfish larvae were stocked at 40 fish/15 L three replicate glass aquaria. Larvae were fed with experimental diets varying FM, BNM, and CM. Proportions of FM : BNM : CM in the experimental diets were: feed 1 (F1) 60:20:20; feed 2 (F2) 40:40:20; feed 3 (F3) 20:60:20; and feed 4 …
Coping styles in farmed fish: consequences for aquaculture
2017
Individual differences in physiological and behavioural responses to stressors are increasingly recognised as adaptive variation and thus raw material for evolution and fish farming improvements including selective breeding. Such individual variation has been evolutionarily conserved and is present in all vertebrate taxa including fish. In farmed animals, the interest in consistent trait associations, that is coping styles, has increased dramatically over the last years because many studies have demonstrated links to performance traits, health and disease susceptibility and welfare. This study will review (i) the main behavioural, neuroendocrine, cognitive and emotional differences between …
Elevated oxidative stress in pied flycatcher nestlings of eumelanic foster fathers under low rearing temperatures
2019
Striking variation in melanin coloration within natural populations is likely due to the different fitness outcomes of alternative phenotypes in varying environmental conditions. There are two types of melanin: eumelanins yield blackish hues, whereas pheomelanins yield reddish hues. The production of eumelanins requires low levels of glutathione (GSH), which is the most important intracellular antioxidant, whereas the production of pheomelanins requires high levels of GSH. We investigated the oxidative status of male pied flycatchers (Ficedula hypoleuca) with different degrees of melanin coloration under different temperatures during the nestling period. Moreover, we assessed the oxidative …
Does education protect against depression? Evidence from the Young Finns Study using Mendelian randomization
2018
Using participants (N = 1733) drawn from the nationally representative longitudinal Young Finns Study (YFS) we estimate the effect of education on depressive symptoms. In 2007, when the participants were between 30 and 45 years old, they reported their depressive symptoms using a revised version of Beck's Depression Inventory. Education was measured using register information on the highest completed level of education in 2007, which was converted to years of education. To identify a causal relationship between education and depressive symptoms we use an instrumental variables approach (Mendelian randomization, MR) with a genetic risk score as an instrument for years of education. The genet…
Re-definition and supporting evidence toward Fanconi Anemia as a mitochondrial disease: Prospects for new design in clinical management
2021
Fanconi anemia (FA) has been investigated since early studies based on two definitions, namely defective DNA repair and proinflammatory condition. The former definition has built up the grounds for FA diagnosis as excess sensitivity of patients' cells to xenobiotics as diepoxybutane and mitomycin C, resulting in typical chromosomal abnormalities. Another line of studies has related FA phenotype to a prooxidant state, as detected by both in vitro and ex vivo studies. The discovery that the FA group G (FANCG) protein is found in mitochondria (Mukhopadhyay et al., 2006) has been followed by an extensive line of studies providing evidence for multiple links between other FA gene products and mi…
Antiepileptogenic Effect of Subchronic Palmitoylethanolamide Treatment in a Mouse Model of Acute Epilepsy
2018
Research on the antiepileptic effects of (endo-)cannabinoids has remarkably progressed in the years following the discovery of fundamental role of the endocannabinoid (eCB) system in controlling neural excitability. Moreover, an increasing number of well-documented cases of epilepsy patients exhibiting multi-drug resistance report beneficial effects of cannabis use. Pre-clinical and clinical research has increasingly focused on the antiepileptic effectiveness of exogenous administration of cannabinoids and/or pharmacologically induced increase of eCBs such as anandamide (also known as arachidonoylethanolamide [AEA]). Concomitant research has uncovered the contribution of neuroinflammatory p…
Did you hear? Auditory prospective memory cues are more beneficial for autistic than for non-autistic children and adolescents
2021
Item does not contain fulltext Background: The transition from primary to secondary school is particularly difficult for autistic children, a transition underpinned by an increase in prospective memory (PM) demands. Aims: To better understand PM in autistic children of the relevant age range and its underlying processes, the current study investigated the impact of cue salience (distinctiveness) on PM in autistic and non-autistic children and adolescents. The study was unique in manipulating the visual and auditory salience of PM cues. Salient cues are assumed to put lower demands on executive control resources as compared to cues that blend in with the ongoing activity. Methods and procedu…
Lamotrigine use in pregnancy and risk of orofacial cleft and other congenital anomalies
2016
Objective: To test previous signals of a risk of orofacial cleft (OC) and clubfoot with exposure to the antiepileptic lamotrigine, and to investigate risk of other congenital anomalies (CA).Methods: This was a population-based case–malformed control study based on 21 EUROCAT CA registries covering 10.1 million births (1995–2011), including births to 2005 in which the clubfoot signal was generated and a subsequent independent study population of 6.3 million births. A total of 226,806 babies with CA included livebirths, stillbirths, and terminations of pregnancy following prenatal diagnosis. First-trimester lamotrigine monotherapy exposure in OC cases and clubfoot cases was compared to other …
Liepājas pilsēta 1919.gada vasarā-ziemā: militārais faktors
2016
Liepājas, kā svarīga tirdzniecības un militāro sakaru centra, nozīme Latvijas Neatkarības kara laikā, bija īpaši augsta. Liepāja notiekošās kaujas un to ietekme bija galvenais faktors Latvijas armijas panākumiem Kurzemes atbrīvošanā no Bermonta armijas. Darba mērķis ir analizēt militāros procesus Liepājā, sākot ar jūnija beigām, kad strauji mainījās situācija, līdz decembra beigām, kad Liepāja un visa Lejaskurzeme jau bija atbrīvota. Mērķa sasniegšanai uzstādīti uzdevumi: gūt ziņas par situāciju Latvijā, sākot ar 1919. gada vasaru līdz rudenim; apskatīt un analizēt Liepājas garnizona attīstību, Sabiedroto misijas darbību un militārās sagatavošanās darbus Liepājā, 1919. gada jūlijā – oktobrī…