Search results for "IFA"
showing 10 items of 620 documents
Associations of the FTO rs9939609 and the MC4R rs17782313 polymorphisms with type 2 diabetes are modulated by diet, being higher when adherence to th…
2012
Background: Although the Fat Mass and Obesity (FTO) and Melanocortin-4 Receptor (MC4R) genes have been consistently associated with obesity risk, the association between the obesity-risk alleles with type 2 diabetes is still controversial. In some recent meta-analyses in which significant results have been reported, the associations disappeared after adjustment for body mass index (BMI). However gene-diet interactions with dietary patterns have not been investigated. Our main aim was to analyze whether these associations are modulated by the level of adherence to the Mediterranean Diet (MedDiet). Methods: Case-control study in 7,052 high cardiovascular risk subjects (3,430 type 2 diabetes c…
Multilayered cultural identity and the perception of the self
2012
This qualitative study examines the reciprocal relationship between a person’s multilayered cultural identity (MCI) and the concept of self (CoS), that is presented purely on a theoretical level and encompasses various theories. Nowadays, in an increasingly globalising world, it is not enough to merely look at a national, ethnic or other type of identity. It is important to realise that there are different layers in an identity that one can view themselves through. The ways an individual perceives themselves through their multicultural background can also be different. This thesis helps identify the ways a person can see themselves. The thesis also attempts to explain the varied nature of o…
Loores a San Bonifacio martir.
El full orlat Grav. xil. enmarcat del Sant, flanquejat per gerros amb flors Text del goig a tres col. separades per bandes
Potential pitfalls in fetal neurosonography
2005
Objective To present anatomic variants of the fetal brain and artifacts related to scanning techniques that could be misinterpreted as abnormalities on prenatal neurosonographic studies. Methods The findings were derived from fetal neurosonographic studies performed routinely from 16 to 36 weeks' gestation during the last 3 years, supervised by a sonologist specialized in neonatal cranial sonography. Results The pitfalls were divided into three groups: brain parenchyma, ventricular system and choroid plexus. We provide images of these pseudolesions and clues to their differentiation from true brain pathology. Conclusions Knowledge of misleading images seen on fetal neurosonographic studies …
Stones, Bones, and Hillfort: Radiocarbon Dating of Ķivutkalns Bronze-Working Center
2013
The Bronze Age site of ķivutkalns with its massive amount of archaeological artifacts and human remains is considered the largest bronze-working center in Latvia. The site is a unique combination of cemetery and hillfort believed to be built on top of each other. This work presents new radiocarbon dates on human and animal bone collagen that somewhat challenge this interpretation. Based on analyses using a Bayesian modeling framework, the present data suggest overlapping calendar year distributions for the contexts within the 1st millennium BC. The carbon and nitrogen isotopic ratios indicate mainly terrestrial dietary habits of studied individuals and nuclear family remains buried in one o…
Fighting mycobacterial infections by antibiotics, phytochemicals and vaccines.
2011
Buruli ulcer is a neglected disease caused by Mycobacterium ulcerans and represents the world's third most common mycobacterial infection. It produces the polyketide toxins, mycolactones A, B, C and D, which induce apoptosis and necrosis. Clinical symptoms are subcutaneous nodules, papules, plaques and ulcerating oedemae, which can enlarge and destroy nerves and blood vessels and even invade bones by lymphatic or haematogenous spread (osteomyelitis). Patients usually do not suffer from pain or systematic inflammation. Surgery is the treatment of choice, although recurrence is common and wide surgical excisions including healthy tissues result in significant morbidity. Antibiotic therapy wit…
Specification of Business Components
2003
Component-based software development is a potential reuse paradigm for the future. While the required technologies for a component-style system development are widely available, for instance Sun's Enterprise Java Beans, a problem inhibits the breakthrough of the component paradigm in business applacation domains: compared to traditional engineering disciplines there is a lack of standardized methods to describe business components. Such a description has to address several aspects: What services are offered and requested by a business component? How can these services be used? Are there any interdependencies between the services of a set of business components? What quality characteristics …
Information Systems and Business Strategy
2003
The main purpose of this chapter is to deep into the importance attached to the Information Systems for the proper formulation of the corporate strategy. After introducing the basis of the strategic planning tradition model, which suggests the subordination of the Information Systems (IS) to the Business Strategy, we propose a new model that views the IS as an strategic instrument suited for the strategy formulation stage, rather than operational tools for the strategy control phase. Success in the application of this model we call “Concurrent Business/IS Strategic Planning Model” will closely depend on the consistency, coherence and soundness of the IS, both internal and external. In order…
Business Process Reference Models: Survey and Classification
2006
Within the Information Systems field, reference models are well-known for many years. The aim of this paper is to survey and to describe reference models for business processes. Our analysis of 30 process reference models is based on a framework consisting of criteria such as application domain, used process modeling languages, model's size, known evaluations and applications of process reference models. Furthermore, we identify model domains, which have been dealt with, describe similarities and differences between the available process reference models, and point to open research questions.
From Organization Business Model to Information System: One Approach and Lessons Learned
2011
The system ISTechnology and lessons learned of its use in the business modeling and development of information systems are analyzed in the paper. The system consists of the meta-model and applications. The meta-model enables to define a platform independent business model of the organization. The applications provide the definition and interpretation of the business model. Interpretation of the business model provides functionality of the information system in the selected platform. The lessons learned confirm that the development and maintenance cost of information systems can be significantly reduced by use of the ISTechnology.