Search results for "IFS"

Posada en valor de la pintura mural gòtica lineal a territori valencià. Un cas a descobrir: el Palau-Castell de Llutxent

2016

Determination of enrichment factors for modified RNA in MeRIP experiments

2019

In the growing field of RNA modification, precipitation techniques using antibodies play an important role. However, little is known about their specificities and protocols are missing to assess their effectiveness. Here we present a method to assess enrichment factors after MeRIP-type pulldown experiments, here exemplified with a commercial antibody against N6-methyladenosine (m6A). Testing different pulldown and elution conditions, we measure enrichment factors of 4-5 using m6A-containing mRNAs against an unmodified control of identical sequence. Both types of mRNA carry 32P labels at different nucleotides, allowing their relative quantification in a mixture after digestion to nucleotides…

Pratique de l'enseignement de l'anglais dans les facultés de médecine en France métropolitaine

2007

Abstract English lessons have been compulsory in French medical schools since the 18th March 1992 bill. Objectives: The aim of this work is to describe the characteristics of this teaching programme as it exists in 2005. Methods: A questionnaire designed by experts in the teaching of medical English was sent to the 41 medical schools in Metropolitan France. The questionnaire covered five different areas (the number of hours of lessons, of students and of teachers; evaluation and marking methods; lesson contents and pedagogical methods; student and teacher profiles; the teaching of English for postgraduate students). Results: Twenty-six questionnaires have been returned and evaluated, which …

Sarraute's plays : poplyphony and enunciation

2014

The corpus is formed of six plays of Nathalie Sarraute; it hides a duplication of enunciation types in the characters’ dialogue. This duplication is latent due to personal pronouns and verb tenses’ neutralization. The transition from an enunciation layer to another is not marked at all or not traditionally marked. Therefore, deciphering will be more complicated to any reader, listener or spectator. These works of art are also highly polyphonic in terms of enunciation as in semantics, as several voices are intertwined and as the characters resort to authorities of point of view. Thus, readers, listeners and spectators should identify enunciation sources and “other” authorities of point of vi…

The tools like evidences of metal working? : strike supports, abrasives and burnishers, sharpening tools and crushing tools

2013

Lots of lithic tools are present in Metal Ages, but few are studied. In metal production, they are especially constitued by strike supports, abrasives, burnishers, sharpening tools and crushing tools. A part of them are in metal ( strike supports) or in ceramic (abrasives, sharpening tools). Contemporary forms of these tools are too different to permit a dierct comparison. It is necessary to work on the function of the tools, deduced from the analysis of these structure. Strike supports used for metal working are easily identifiable. They allow to reproduce more or less precisely the objects that they were fabricated with. Abrasives are difficult to relate to a material, but the traces of u…

A rhamnose-binding lectin from sea bass (Dicentrarchus labrax) plasma agglutinates and opsonizes pathogenic bacteria

2014

Abstract The discovery of rhamnose-binding lectins (RBLs) in teleost fish eggs led to the identification of a novel lectin family characterized by a unique sequence motif and a structural fold, and initially proposed to modulate fertilization. Further studies of the RBL tissue localization and gene organization were also suggestive of role(s) in innate immunity. Here we describe the purification, and biochemical and functional characterization of a novel RBL (DlRBL) from sea bass (Dicentrarchus labrax) serum. The purified DlRBL had electrophoretic mobilities corresponding to 24 kDa and 100 kDa under reducing and non-reducing conditions, respectively, suggesting that in plasma the DlRBL is p…

Militer pour Artisans du monde et Max Havelaar. Etude de cas des acteurs associatifs et militants du commerce équitable dijonnais

2007

National audience

Development of a scale of perceived stressors specific to ICU: the PS-ICU scale

2019

International audience

A human CCT5 gene mutation causing distal neuropathy impairs hexadecamer assembly in an archaeal model

2014

Chaperonins mediate protein folding in a cavity formed by multisubunit rings. The human CCT has eight non-identical subunits and the His147Arg mutation in one subunit, CCT5, causes neuropathy. Knowledge is scarce on the impact of this and other mutations upon the chaperone's structure and functions. To make progress, experimental models must be developed. We used an archaeal mutant homolog and demonstrated that the His147Arg mutant has impaired oligomeric assembly, ATPase activity, and defective protein homeostasis functions. These results establish for the first time that a human chaperonin gene defect can be reproduced and studied at the molecular level with an archaeal homolog. The major…

Santé du sportif, conditions suspensives et contrat de travail à durée déterminée

2008

International audience; Besançon, 16 novembre 2007, n° 06/02597