Search results for "IMPACT"

showing 10 items of 1703 documents

Effects on the incidence of cardiovascular events of the addition of pioglitazone versus sulfonylureas in patients with type 2 diabetes inadequately …

2017

Background The best treatment option for patients with type 2 diabetes in whom treatment with metformin alone fails to achieve adequate glycaemic control is debated. We aimed to compare the long-term effects of pioglitazone versus sulfonylureas, given in addition to metformin, on cardiovascular events in patients with type 2 diabetes. Methods TOSCA.IT was a multicentre, randomised, pragmatic clinical trial, in which patients aged 50–75 years with type 2 diabetes inadequately controlled with metformin monotherapy (2–3 g per day) were recruited from 57 diabetes clinics in Italy. Patients were randomly assigned (1:1), by permuted blocks randomisation (block size 10), stratified by site and…

MaleDiabetes and Metabolism ipoglycemic drugs cardiovascualr eventSettore MED/09 - Medicina Internaendocrine system diseasesIMPACTpioglitazone versus sulfonylureasEndocrinology Diabetes and MetabolismGLIMEPIRIDEDiabetes cardiovascular events metformin pioglitazone sulphonylureasType 2 diabetes030204 cardiovascular system & hematologyInternal Medicine; Endocrinology Diabetes and Metabolism; Endocrinologylaw.inventionSettore MED/13 - EndocrinologiaGlibenclamide0302 clinical medicineRandomized controlled triallawGLYCEMIC CONTROLGliclazideInternal medicinediabetes and metabolismRISKeducation.field_of_studydiabetesIncidenceInternal medicine; endocrinology diabetes and metabolism; endocrinologyMiddle AgedINSULINMetforminMetforminTreatment OutcomeEditorialsulphonylureasCardiovascular DiseasesCombinationDrug Therapy CombinationFemaleType 2medicine.drugmedicine.medical_specialtyPopulation030209 endocrinology & metabolismAged; Cardiovascular Diseases; Diabetes Mellitus Type 2; Drug Therapy Combination; Female; Humans; Hypoglycemic Agents; Incidence; Male; Metformin; Middle Aged; Pioglitazone; Sulfonylurea Compounds; Thiazolidinediones; Treatment OutcomeCardiovascular events03 medical and health sciencesendocrinologyGLUCOSE-LOWERING DRUGSDrug TherapyInternal medicineDiabetes MellitusmedicineHumansHypoglycemic AgentssulfonylureaseducationTOSCA.ITAgedPioglitazonebusiness.industryMORTALITYnutritional and metabolic diseasesInsulin resistancemedicine.diseaseSurgeryGlimepirideSulfonylurea CompoundsDiabetes Mellitus Type 2Diabetes Mellitus; Pioglitazone; Insulin resistanceThiazolidinedionesbusinessFOLLOW-UPPioglitazone
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Translation and Test–Retest of the Spanish Podiatry Health Questionnaire (PHQ-S)

2018

Background: The Podiatric Health Questionnaire (PHQ) is a health-related questionnaire consisting of six questions designed for measuring foot health status. To date, the PHQ has only been validated in the English-language version. Thus, this study aimed to perform the Spanish translation and test&ndash

MaleEncuestaVisual Analog ScaleIntraclass correlationHealth Toxicology and MutagenesisHealth StatusCalidad de vidalcsh:MedicineWalking0302 clinical medicineQuality of lifeSurveys and QuestionnairesMedicine030212 general & internal medicineCiencias médicasReliability (statistics)media_commonLanguagePain MeasurementHygieneMiddle AgedhumanitiesTest (assessment)EncuestasExtremitatsPodologíahealth impact assessmentFemaleHealth Impact AssessmentWorryQuality of lifeAdultmedicine.medical_specialtymedia_common.quotation_subjectPainEnquestesbehavioral disciplines and activitiesArticle03 medical and health sciencesCronbach's alphamental disordersHumansTranslationsvalidation studies030203 arthritis & rheumatologybusiness.industryFootlcsh:RPublic Health Environmental and Occupational HealthPodiatryReproducibility of ResultsConfidence intervalSelf ConceptValidation studiesquality of lifeSpainfootPhysical therapybusiness
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The unfortunate generation: stroke survivors in Riga, Latvia

2003

Abstract The poor health status of citizens in post-Soviet states has been reported but few studies have investigated the illness experiences of people in those countries. This paper reports findings from an interview study conducted with stroke patients in Riga, Latvia, who were part of a cohort recruited over 1 year for a European study comparing the provision of care, outcomes and resource use. The interview study aimed to elicit stroke patients’ own perceptions of the impact of stroke 1 year after the event. Adopting a phenomenological perspective we illustrate how the particular social setting shapes stroke as an illness, its influences on access to health care and on consideration of …

MaleGerontologymedicine.medical_specialtyHealth (social science)HistoryContext (language use)Health Services AccessibilityCohort StudiesInterviews as TopicLife Change EventsHistory and Philosophy of ScienceSickness Impact ProfileActivities of Daily LivingHealth caremedicineHumansDisabled PersonsSurvivorsSocial ChangeStrokeQualitative ResearchAgedAged 80 and overPovertybusiness.industryPublic healthStroke RehabilitationSocial SupportLatvianMiddle Agedmedicine.diseaseLatvialanguage.human_languageStrokeCohortlanguageFemaleHealth ExpendituresBasic needsbusinessAttitude to HealthDemographySocial Science & Medicine
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Gender Differences in Psychological Stress Factors of Physical Therapy Degree Students in the COVID-19 Pandemic: A Cross-Sectional Study

2022

(1) Background: The aim of the study was to investigate how the COVID-19 pandemic impacted the mental health and quality of life of male and female physical therapy students at the European University of Madrid. (2) Methods: A cross-sectional online survey was conducted including a range of tests capturing different domains: 36-item Short Form Health Survey, six-item state version of the State–Trait Anxiety Inventory, Acceptance and Action Questionnaire, Three Items Loneliness Scale, four-item version of the Perceived Stress Scale, Beck Depression Inventory revised version, and Sleep Quality Numeric Rating Scale. (3) Results: A total of 151 students completed the study, consisting of 78 fem…

MaleHealth Toxicology and MutagenesisCOVID-19 pandemicSpanishAnxietyArticleSex Factorsphysical therapy studentsHumanspsychological impact; COVID-19 pandemic; physical therapy students; SpanishStudentsPsychological impactPandemicsPhysical Therapy ModalitiesDepressionSARS-CoV-2RPublic Health Environmental and Occupational HealthCOVID-19Cross-Sectional StudiesSleep QualityQuality of LifeMedicineFemalepsychological impactPhysical therapy studentsStress PsychologicalInternational Journal of Environmental Research and Public Health; Volume 19; Issue 2; Pages: 810
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Association of Osteoarthritis with Increased Risk of Cardiovascular Diseases in the Elderly: Findings from the Progetto Veneto Anziano Study Cohort

2015

Objective The possible relevance of osteoarthritis (OA) as a cardiovascular disease (CVD) risk factor is still debated. The aim of this study was to investigate the association between OA and the onset of CVD in older individuals. Methods Among a sample of 3,099 elderly subjects, 2,158 were identified as having no CVD at baseline and were followed up for a mean ± SD 4.4 ± 1.2 years. OA was defined using a standardized algorithm that investigated disease history, medical documentation (including radiographic reports), symptoms, and physical examination of the joints. Incident CVD was defined as the onset of coronary artery disease, heart failure, stroke/transient ischemic attack, peripheral …

MaleIMPACTImmunologyUNITED-STATESPROGRESSIONCoronary Artery DiseaseKNEE OSTEOARTHRITISNOCohort StudiesPeripheral Arterial DiseaseRheumatologyImmunology; Immunology and Allergy; RheumatologyRisk FactorsOsteoarthritisEPIDEMIOLOGYHumansImmunology and AllergyObesityAgedDyslipidemiasProportional Hazards ModelsAged 80 and overHeart FailureDISABILITYMORTALITYIncidencePREVALENCEHospitalizationLipoproteins LDLStrokeATHEROSCLEROSISItalyCardiovascular DiseasesIschemic Attack TransientHypertensionFemaleARTHRITISFollow-Up Studies
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Retirement age and type as predictors of frailty : a retrospective cohort study of older businessmen

2020

ObjectivesTo study the association between retirement characteristics and frailty in a homogenous population of former business executives.DesignCross-sectional cohort study using data from the Helsinki Businessmen Study.SettingHelsinki, Finland.Participants1324 Caucasian men, born in 1919–1934, who had worked as business executives and managers and of whom 95.9% had retired by the year 2000. Questions on age at and type of retirement, lifestyle and chronic conditions were embedded in questionnaires.Primary and secondary outcome measuresFrailty assessed according to a modified phenotype definition at mean age 73.3 years.ResultsMean age at retirement was 61.3 years (SD 4.3) and 37.1% had ret…

MaleIMPACToccupational & industrial medicineCohort Studies0302 clinical medicineEpidemiologyMedicineEMPLOYMENT1506030212 general & internal medicineSTATE PENSION AGEHEALTH EVIDENCEkohorttitutkimusFinlandAged 80 and overGeriatricsRISKRetirementeducation.field_of_studyFrailtyindustrial medicinepublic healthRMENGeneral MedicineMiddle AgedWORKINGMedicineeläkeikäepidemiologyoccupational &amp1716ikääntyneetMIDLIFECohort studymedicine.medical_specialtyFrail ElderlyPopulation03 medical and health sciencesHumanseducationAgedRetrospective StudiesOccupational and Environmental Medicinebusiness.industrygeriatric medicinePublic healthMORTALITYRetrospective cohort studyCross-Sectional StudiesikääntyminenAgeing3121 General medicine internal medicine and other clinical medicineeläkkeelle siirtyminenTRAJECTORIESbusiness030217 neurology & neurosurgeryRetirement agehauraus-raihnausoireyhtymäDemography
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Hospital readmission rates: signal of failure or success?

2013

AbstractHospital readmission rates are increasingly used as signals of hospital performance and a basis for hospital reimbursement. However, their interpretation may be complicated by differential patient survival rates. If patient characteristics are not perfectly observable and hospitals differ in their mortality rates, then hospitals with low mortality rates are likely to have a larger share of un-observably sicker patients at risk of a readmission. Their performance on readmissions will then be underestimated. We examine hospitals’ performance relaxing the assumption of independence between mortality and readmissions implicitly adopted in many empirical applications. We use data from th…

MaleMORTALITY-RATESEconomicsIMPACTSocial SciencesHospital performanceC50Business & EconomicsReadmission ratesmedia_commonAged 80 and overHip fractureOUTCOMESI18Mortality rateHealth PolicyHEALTH CARE SCIENCES & SERVICESHospitalsSurvival RateEngland1117 Public Health And Health ServicesMortality ratesFemaleMedical emergencyHEALTHLife Sciences & BiomedicineSample selectionmedicine.medical_specialtyACUTE MYOCARDIAL-INFARCTIONmedia_common.quotation_subjectBivariate analysisPatient ReadmissionReadmission ratemedicineQUALITYHumansSurvival rate1402 Applied EconomicsSelection (genetic algorithm)AgedQuality of Health CareSelection biasHospital readmissionSAMPLE SELECTIONScience & TechnologyModels Statisticalbusiness.industryHip FracturesPublic Health Environmental and Occupational HealthHIP FRACTUREHEALTH POLICY & SERVICESmedicine.diseaseMortality rateMODELEmergency medicinebusinessRACOSTS
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Effect of the local administration of betamethasone on pain, swelling and trismus after impacted lower third molar extraction. A randomized, triple b…

2013

Objectives: The aim of this study is to compare the analgesic and anti-inflammatory effects of the local postoperative administration of a single 12-mg dose of betamethasone after the surgical removal of impacted lower third molars. Study Design: A split-mouth, triple-blind, randomized, placebo-controlled clinical trial of 25 patients requiring the surgical removal of symmetrical lower third molars was performed. In the experimental side, a 12-mg dose of betamethasone was administered submucosally after the surgical procedure, while in the control side a placebo (sterile saline solution) was injected in the same area. To assess postoperative pain, visual analogue scales and the consumption …

MaleMolarAdministration TopicalAnti-Inflammatory AgentsTrismusBetamethasonelaw.inventionPostoperative ComplicationsClinical trialsRandomized controlled triallawEdemaAntiinflammatory agentsEdemaTeeth extractionMedicineProspective StudiesExtracció dentalPain PostoperativeAnalgesicsTooth ImpactedAgents antiinflamatorisDent molar:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludAnesthesiaUNESCO::CIENCIAS MÉDICASBetamethasoneFemaleOral Surgerymedicine.symptommedicine.drugmedicine.medical_specialtyAnalgesicOdontologíaPlaceboYoung AdultAnalgèsicsDouble-Blind MethodHumansGeneral Dentistrybusiness.industryResearchMolarSurgeryClinical trialOtorhinolaryngologyTooth ExtractionMolar ThirdTrismusSurgerybusinessAssaigs clínicsMedicina Oral Patología Oral y Cirugia Bucal
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Impaction of permanent mandibular second molar: A retrospective study

2013

Objective: To determine the prevalence of impacted mandibular second molar (MM2) and the association between MM2 impaction and crowding. The clinical significance of the angle between first and second mandibular molar and of the space between the first mandibular molar (MM1) and the anterior margin of mandibular ramus in MM2 impaction were also evaluated. Material and Methods: In this retrospective study , from the dental records of 2,945 caucasian young orthodontics patients, 40 subjects with MM2 impaction were included in a study group (SG) and compared with a control group (CG) of 200 subjects without MM2 impactions. The crowding, the angle of inclination of MM2, the distance between MM1…

MaleMolarDentistryOdontologíaMandibleMandibular second molarstomatognathic systemPrevalenceimpactionHumansMedicineimpaction; orthodontics; impacted mandibular second molarGeneral DentistryRetrospective StudiesRoot formationOrthodonticsOral Medicine and Pathologybusiness.industryImpactionimpacted mandibular second molarTooth ImpactedMandibleRetrospective cohort study:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludMolarCrowdingOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASResearch-ArticleFemaleSurgerysense organsbusinessorthodonticsMandibular molar
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Dental anomalies in a Portuguese population

2013

The aim of this study was to evaluate the prevalence and pattern of agenesis, supernumerary teeth, impacted teeth and transpositions, as well as the relation between them, in a Portuguese sample.The study sample consisted of 2888 patients, observed between 2005 and 2009 at the Dentistry Clinic of the Instituto Superior de Ciências da Saúde-Norte (ISCSN, Portugal). The study included evaluation of the following parameters: agenesis of all teeth, supernumerary teeth, impacted permanent teeth and tooth transposition. The age range varied from 7 to 21 years. In order to study the absence of the third molar, subjects aged below 14 years were excluded. Statistical analysis was performed using SPS…

MaleMolarTooth eruptionDentistryOrthodonticsstomatognathic systemPrevalenceHumansMedicineSupernumeraryChildAnodontiaPermanent teethOrthodonticsTooth Eruption EctopicPortugalbusiness.industryTooth Impactedmedicine.diseasestomatognathic diseasesHypodontiaTooth SupernumeraryAgenesisFemalePortuguese populationTooth agenesisbusinessInternational Orthodontics
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