Search results for "IMPAIRMENT"

The role of linguistic and cognitive factors in emotion recognition difficulties in children with ASD, ADHD or DLD

2020

Abstract Background: Many children with neurodevelopmental disorders such as autism spectrum disorder (ASD), attention deficit hyperactivity disorder (ADHD) or developmental language disorder (DLD) have difficulty recognizing and understanding emotions. However, the reasons for these difficulties are currently not well understood. Aims: To compare the emotion recognition skills of children with neurodevelopmental disorders as well as those children’s skills with the skills of their typically developing (TD) age peers. Also, to identify the role of underlying factors in predicting emotion recognition skills. Methods & Procedures: The 6–10‐year‐old children (n = 50) who participated in th…

Quantitative EEG differentiates multiple sclerosis with and without cognitive impairment from healthy controls at the beginning of the disease: preli…

2018

Background and aims: The present study aims to assess possible qEEG differences between newly diagnosed multiple sclerosis (MS) patients with or without cognitive impairment (CI). Methods: We enrolled 22 patients (18-55-years-old) treated with first-line drugs for <6 months, and 11 healthy controls. All subjects underwent neuropsychological assessment including BICAMS and BDI. EEG recordings were performed during a cognitive task (computerised “SDMT” subtest of BICAMS) and at rest. Based on neuropsychological assessment, patients were considered as affected (MSCI group) or not (MS group) by cognitive impairment. We analysed data comparing MSCI patients matched by sex, age (±5years) and e…

Anodal Transcranial Direct Current Stimulation Over Prefrontal Cortex Slows Sequence Learning in Older Adults

2022

Aging is associated with declines in sensorimotor function. Several studies have demonstrated that transcranial direct current stimulation (tDCS), a form of non-invasive brain stimulation, can be combined with training to mitigate age-related cognitive and motor declines. However, in some cases, the application of tDCS disrupts performance and learning. Here, we applied anodal tDCS either over the left prefrontal cortex (PFC), right PFC, supplementary motor complex (SMC), the left M1, or in a sham condition while older adults (n = 63) practiced a Discrete Sequence Production (DSP), an explicit motor sequence, task across 3 days. We hypothesized that stimulation to either the right or left P…

Human, Technologies and Quality of Education: Proceedings of Scientific Papers, 2020

2020

Tenapanor for the treatment of irritable bowel syndrome with constipation.

2020

Introduction: Irritable bowel syndrome with constipation is associated with higher rates of functional impairment, as compared to other subtypes of the syndrome. Conventional laxative-based pharmacologic therapy of IBS-C, which is mostly symptom-based, is often unsatisfactory. Tenapanor represents a first-in-class orally available inhibitor of NHE3, which is minimally absorbed in the GI tract, what constitutes a significant therapeutic benefit, as it may act on the drug target. Areas covered: Aim of this article is to sum up the evidences about pharmacodynamics and pharmacokinetics of tenapanor, focusing on animal models and in vitro studies, but also discuss clinical trials on tenapanor's …

Esteettömyys digitaalisissa ympäristöissä kielellisten erityisvaikeuksien näkökulmasta

2019

Digitalisoitumisen myötä monet arjessa tarvittavat tiedot ja palvelut ovat siirtyneet teknologiaympäristöihin, joiden käyttö vaatii digitaalista lukutaitoa. Tutkimuksessa tarkasteltiin digitaalisten ympäristöjen esteettömyyttä sellaisten nuorten näkökulmasta, joilla on kielellisiä erityisvaikeuksia (SLI). Tutkimus pyrki osallistamaan näitä nuoria digitaalisten palvelujen suunnitteluun. Digitaalisiksi palveluiksi valittiin mielen hyvinvointia edistäviä sivustoja, sovelluksia ja pelejä, koska SLI-nuorilla on todettu muita useammin mielen hyvinvoinnin pulmia. Tutkimustehtävänä oli selvittää, miten digitaalisten ympäristöjen esteettömyys ilmenee tutkimukseen osallistuneiden SLI-nuorten puheissa…

Co utrudnia opis logopedycznych zjawisk? Od słuchoniemoty, afazji wrodzonej i alalii do specyficznego zaburzenia językowego (SLI)

2016

This article, dedicated to Professor Stanisław Gajda because of his anniversary, raises theoretical issues of accuracy and explicitness of terms used in science which are familiar to him. Logopaedics, by virtue of its interdisciplinary character and exposure to borderline of numerous and often very distant from each other sciences such as anatomy, linguistics or physics, significantly uses appropriate for these sciences tools of descriptions (freąuently doubling notions) and thus, it represents a very good example of discipline in which unnecessary overgrowth of terminology makes it difficult to track research results and ąuality analysis of phenomena. Specific Language Impairment (SLI) is …

Il ruolo della corteccia prefrontale dorsolaterale nella memoria di riconoscimento: uso dellla Stimolazione Magnetica Transcranica per il trattamento…

Il ruolo della corteccia prefrontale dorsolaterale (DLPFC) in compiti di memoria è stato largamente documentato. Una questione ancora molto dibattuta è il grado di lateralizzazione anatomica-funzionale dei processi di controllo esecutivo della DLPFC coinvolti nella memoria di riconoscimento. Il lavoro di tesi indaga le connessioni tra DLPFC e ippocampo mediante l’applicazione di tecniche di neuromodulazione dell’eccitabilità della DLPFC che consentano di accrescere l’attività ippocampale durante compiti di memoria di riconoscimento. I primi tre studi valutano gli effetti inibitori ed eccitatori della rTMS applicata alla DLPFC sulla performance in compiti di memoria di riconoscimento, in div…

Etude de l'impact du contrôle postural associé au port de verres prismatiques dans la réduction des troubles cognitifs chez le dyslexique de développ…

2007

But de l’etude L’objectif de ce travail est d’evaluer l’impact des modifications proprioceptives induites par un traitement postural sur les troubles cognitifs d’une population d’enfants souffrant de dyslexie de developpement. Patients et methodes Il a ete constitue un groupe de 20 enfants dyslexiques traites par prismes posturaux, semelles « de posture » et reeducation posturale, et un groupe temoin de 13 enfants dyslexiques portant uniquement des lunettes sans prismes. Tous les enfants etaient de sexe masculin. Lors de leur inclusion dans l’etude (M0) et 6 mois plus tard (M6), tous les participants ont ete evalues par un bilan ophtalmologique et postural et ont recu un examen neuropsychol…

Educational Impairment in Social Anxiety Disorder and Post-Traumatic Stress Disorder

2020

Tant la Fòbia social (FS) com el Trastorn d’estrès posttraumàtic (TEPT) s’han associat al baix rendiment acadèmic, però els estudis previs presentaven importants limitacions metodològiques. Per a realitzar recerca epidemiològica, és útil utilitzar els registres administratius i de salut poblacionals, com els disponibles a Suècia. Per tal de desenvolupar estudis amb garanties, és important que els codis diagnòstics que contenen aquests registres siguen vàlids i fiables. Aquesta tesi per compendi d’articles té com a primer objectiu validar el codi diagnòstic de l’FS (el codi diagnòstic del TEPT ja ha sigut prèviament validat) per a després explorar, per mitjà dels registres poblacionals suecs…