Search results for "IMPLEMENTATION"

showing 10 items of 345 documents

Biases in study design, implementation, and data analysis that distort the appraisal of clinical benefit and ESMO-Magnitude of Clinical Benefit Scale…

2021

BACKGROUND: The European Society for Medical Oncology-Magnitude of Clinical Benefit Scale (ESMO-MCBS) is a validated, widely used tool developed to score the clinical benefit from cancer medicines reported in clinical trials. ESMO-MCBS scores assume valid research methodologies and quality trial implementation. Studies incorporating flawed design, implementation, or data analysis may generate outcomes that exaggerate true benefit and are not generalisable. Failure to either indicate or penalise studies with bias undermines the intention and diminishes the integrity of ESMO-MCBS scores. This review aimed to evaluate the adequacy of the ESMO-MCBS to address bias generated by flawed design, im…

Data Analysis:técnicas de investigación::métodos::diseño de la investigación [TÉCNICAS Y EQUIPOS ANALÍTICOS DIAGNÓSTICOS Y TERAPÉUTICOS]Cancer Researchbiasmedia_common.quotation_subjectclinical trial reportingESMO-MCBS:Otros calificadores::Otros calificadores::/farmacoterapia [Otros calificadores]ReviewMedical Oncologyclinical trial implementation:Other subheadings::Other subheadings::/drug therapy [Other subheadings]:neoplasias [ENFERMEDADES]:profesiones sanitarias::medicina::medicina interna::oncología médica [DISCIPLINAS Y OCUPACIONES]Neoplasmsclinical trial analysis:Investigative Techniques::Methods::Research Design [ANALYTICAL DIAGNOSTIC AND THERAPEUTIC TECHNIQUES AND EQUIPMENT]Agency (sociology)HumansQuality (business):Health Occupations::Medicine::Internal Medicine::Medical Oncology [DISCIPLINES AND OCCUPATIONS]health care economics and organizationsmedia_commonActuarial scienceManchester Cancer Research CentreCàncer - TractamentResearchInstitutes_Networks_Beacons/mcrcClinical study designHealth technologyGénéralitésPublication biasclinical trial designAssaigs clínics - Disseny:Neoplasms [DISEASES]Clinical trialCritical appraisalOncologyResearch DesignScale (social sciences)PsychologyESMO Open
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Big Data as a Driver for Clinical Decision Support Systems: A Learning Health Systems Perspective

2018

Big data technologies are nowadays providing health care with powerful instruments to gather and analyze large volumes of heterogeneous data collected for different purposes, including clinical care, administration, and research. This makes possible to design IT infrastructures that favor the implementation of the so-called “Learning Healthcare System Cycle,” where healthcare practice and research are part of a unique and synergic process. In this paper we highlight how “Big Data enabled” integrated data collections may support clinical decision-making together with biomedical research. Two effective implementations are reported, concerning decision support in Diabetes and in Inherited Arrh…

Decision support systemProcess (engineering)Computer scienceBig datacomputer.software_genre01 natural sciencesClinical decision support systemlcsh:QA75.5-76.9503 medical and health sciences0302 clinical medicinebig datalcsh:AZ20-999Health care030212 general & internal medicine0101 mathematicsdata analyticsdata integrationImplementationbusiness.industry010102 general mathematicslearning health care cyclelcsh:History of scholarship and learning. The humanitiesData scienceData warehousedata warehouseslcsh:Electronic computers. Computer sciencebusinesscomputerData integrationFrontiers in Digital Humanities
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TOURISM POLICY IN LATVIA - FROM A TOP-DOWN TO A COLLABORATIVE APPROACH

2020

In 2019, Latvia drafted a National Development Plan [NDP 2027] for the next period, which also comprises actions for the development of the tourism sector. Unlike previous practices, approaches to drafting a common plan and developing and implementing tourism policy have changed significantly. The aim of the research is to describe the process of developing a tourism development plan, analyse the use of the latest planning and policy implementation approaches and evaluate the framework of the plan. A qualitative research strategy - a case study was used. The main research methods are document analysis, in-depth interviews and participatory observations. The process of drafting a new tourism…

Development plancollaborative approach; destination cooperation; implementation; tourism policyProcess managementNational Development PlanDominance (economics)Process (engineering)Action planBusinessPlan (drawing)TourismQualitative researchSOCIETY. INTEGRATION. EDUCATION. Proceedings of the International Scientific Conference
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Understanding Contradictions in Enterprise System Implementations: A Case for Stakeholder Theory

2014

Enterprise Systems (ES) implementation is challenging, and handling conflicting interests may be vital for success. Previous research has established how ES implementation involves dialectics, often related to multiple stakeholders. Involved stakeholders have in previous studies been analyzed in a power perspective, through the lens of organizational influence processes. Stakeholder theory (ST) takes a wider perspective, by including legitimacy and urgency in addition to power. An interesting perspective is therefore a suggested combination of ST and dialectics. This paper presents an ES implementation case where the explicit combination of ST and dialectics was tried out in the data analys…

DialecticEnterprise systemKnowledge managementProcess (engineering)business.industryPerspective (graphical)BusinessStakeholder theoryOutcome (game theory)ImplementationLegitimacy
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Parallel laser micromachining based on diffractive optical elements with dispersion compensated femtosecond pulses

2013

We experimentally demonstrate multi-beam high spatial resolution laser micromachining with femtosecond pulses. The effects of chromatic aberrations as well as pulse stretching on the material processed due to diffraction were significantly mitigated by using a suited dispersion compensated module (DCM). This permits to increase the area of processing in a factor 3 in comparison with a conventional setup. Specifically, 52 blind holes have been drilled simultaneously onto a stainless steel sample with a 30 fs laser pulse in a parallel processing configuration.

DiffractionFemtosecond pulse shapingMaterials scienceChromatic aberrationElectromagnetic pulseDiffraction efficiencyEngineering controlled termsUltrashort pulseslaw.inventionOpticslawLaser micro-machiningChromatic aberrationParallel processingDispersionsElectromagnetic pulseHigh spatial resolutionbusiness.industryEngineering main headingLaserBlind holesAtomic and Molecular Physics and OpticsAberrationsPulse stretchingParallel processing (DSP implementation)Fs laser pulseFemtosecondbusinessOptics Express
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Implementation of pattern recognition algorithm based on RBF neural network

2002

In this paper, we present implementations of a pattern recognition algorithm which uses a RBF (Radial Basis Function) neural network. Our aim is to elaborate a quite efficient system which realizes real time faces tracking and identity verification in natural video sequences. Hardware implementations have been realized on an embedded system developed by our laboratory. This system is based on a DSP (Digital Signal Processor) TMS320C6x. The optimization of implementations allow us to obtain a processing speed of 4.8 images (240x320 pixels) per second with a correct rate of 95% of faces tracking and identity verification.

Digital signal processorArtificial neural networkPixelComputer sciencebusiness.industryPattern recognitionPattern recognition (psychology)Identity (object-oriented programming)Radial basis functionComputer visionArtificial intelligencebusinessAlgorithmImplementationDigital signal processingSPIE Proceedings
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Dissemination/Communication Report. Period concerning this report: 01.01.2018-31.12.2018.

2018

During the first year of the project implementation different dissemination/communication activities were carried out. First scientific results were presented on the 18th European Conference on Composite Materials (ECCM). For the dissemination of information among general public professional FACEBOOK profile was developed. Additionally, for better dissemination of project scientific results project profile “Environmental effects on physical properties of smart composites and fibre-reinforced plastics modified by carbonaceous nanofillers for structural applications” was developed at open-access database ZENODO (www.zenodo.org) under community POSTDOC-Latvia providing open-access to all publi…

Dissemination/Communication Reportproject implementationPOSTDOC Latvia:TECHNOLOGY [Research Subject Categories]
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First Measurement of Transverse-Spin-Dependent Azimuthal Asymmetries in the Drell-Yan Process

2017

The first measurement of transverse-spin-dependent azimuthal asymmetries in the pion-induced Drell-Yan (DY) process is reported. We use the CERN SPS 190 GeV/$c$, $\pi^{-}$ beam and a transversely polarized ammonia target. Three azimuthal asymmetries giving access to different transverse-momentum-dependent (TMD) parton distribution functions (PDFs) are extracted using dimuon events with invariant mass between 4.3 GeV/$c^2$ and 8.5 GeV/$c^2$. The observed sign of the Sivers asymmetry is found to be consistent with the fundamental prediction of Quantum Chromodynamics (QCD) that the Sivers TMD PDFs extracted from DY have a sign opposite to the one extracted from semi-inclusive deep-inelastic sc…

Drell-Yan process550ComputerSystemsOrganization_COMPUTERSYSTEMIMPLEMENTATIONNuclear TheoryGeneral Physics and Astronomyparton: distribution functiontransverse momentum dependence01 natural sciencesCOMPASSHigh Energy Physics - ExperimentSivers functionHigh Energy Physics - Experiment (hep-ex)semi-inclusive reaction [deep inelastic scattering]High Energy Physics - Phenomenology (hep-ph)ddc:550[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Nuclear ExperimenttransversityPhysicsQuantum chromodynamics(muon+ muon-) [mass spectrum]Large Hadron Colliderdeep inelastic scattering: semi-inclusive reactionpolarized target: transverse190 GeV/ctransverse [polarized target]nucleonDrell–Yan processhep-phdimuon: mass spectrumAzimuthHigh Energy Physics - PhenomenologyTransverse planeasymmetry [angular distribution]pi- nucleus: scatteringmass spectrum [dimuon]distribution function [parton]Nucleonspin: asymmetryParticle Physics - ExperimentParticle physicsangular distribution: asymmetryscattering [pi- nucleus]ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISIONFOS: Physical sciencesComputerApplications_COMPUTERSINOTHERSYSTEMSAccelerator Physics and InstrumentationGeneralLiterature_MISCELLANEOUSNuclear physicsPhysics and Astronomy (all)[ PHYS.HEXP ] Physics [physics]/High Energy Physics - Experiment [hep-ex]0103 physical sciencesquantum chromodynamicsuniversality010306 general physicsParticle Physics - Phenomenology010308 nuclear & particles physicshep-exHigh Energy Physics::PhenomenologyAcceleratorfysik och instrumenteringCERN SPSmass spectrum: (muon+ muon-)ComputingMethodologies_PATTERNRECOGNITION[PHYS.HPHE]Physics [physics]/High Energy Physics - Phenomenology [hep-ph]Physics::Accelerator Physics[ PHYS.HPHE ] Physics [physics]/High Energy Physics - Phenomenology [hep-ph]High Energy Physics::Experimentasymmetry [spin]experimental results
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Accelerating short read mapping on an FPGA (abstract only)

2012

The explosive growth of short read datasets produced by high throughput DNA sequencing technologies poses a challenge to the mapping of short reads to a reference genome in terms of sensitivity and execution speed. Existing methods often use a restrictive error model for computing the alignments to improve speed, whereas more flexible error models are generally too slow for large-scale applications. Although a number of short read mapping software tools have been proposed, designs based on hardware are relatively rare. In this paper, we present a hybrid system for short read mapping utilizing both software and field programmable gate array (FPGA)-based hardware. The compute intensive semi-g…

Dynamic programmingSpeedupSoftwareParallel processing (DSP implementation)Computer sciencebusiness.industryHybrid systemSensitivity (control systems)Parallel computingShort readbusinessField-programmable gate arrayProceedings of the ACM/SIGDA international symposium on Field Programmable Gate Arrays
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The Role of Contextual Factors in the Influence of ICT on Street-Level Discretion

2017

Public service workers in the frontline have traditionally enjoyed a wide freedom to make decisions during policy implementation. Research shows that technology has both constraining and enabling effects on public service workers affecting their ability to exercise discretion. What remains unclear is under which circumstances discretion is influenced by technology. Using a case study approach and drawing on neo-institutional theory, this paper studies a court to identify contextual factors affecting the phenomenon. Findings show that technology has no unilateral effect on street-level discretion, and is found moderated by contextual factors such as the degree of social complexity in a case,…

E-Governmentbusiness.industrymedia_common.quotation_subject05 social sciencesSocial complexityPublic relationsStreet-level bureaucracyDiscretion0506 political scienceInformation and Communications TechnologyPhenomenon0502 economics and businessPolicy implementation050602 political science & public administrationPublic serviceBusiness050203 business & managementmedia_commonProceedings of the 50th Hawaii International Conference on System Sciences (2017)
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