Search results for "IMPR"
showing 10 items of 1334 documents
Biznesa procesu reorganizācija komercbankās
2020
Bakalaura darba tēma ir “Biznesa procesu reorganizācija komercbankās”. Bakalaura darba mērķis ir analizēt, kā biznesa procesu reorganizācija tika ieviesta PSB bankā Krievijā, un novērtēt tās ietekmi uz banku un tās klientiem. Darba saturs ir sadalīts trīs daļās. Pirmajā daļā tiek sniegts teorētiskais atspoguļojums ar piedāvātajām biznesa procesu reorganizācijas definīcijām un teorijām (turpmāk - BPR). Darba otrajā daļā ir ietverta vispārīga informācija par PSB Banku Krievijā, un ieviestās BPR analīze. Darba pēdējā daļa ir empīrisks pētījums, kas sniedz kvantitatīvu analīzi par BRP ietekmi, kas ieviesta PSB bankā, Krievijā.
The Relevance of Systemic Approaches in Business Sciences
2015
Our times are characterized by intense changes in the viable logics of markets and, generally speaking, of business systems. Business scenarios today are typified by connectivity, dynamism, nonlinearity, and emergent behaviors - in other words by “complexity” (Dominici, 2012). Reductionist models are unable to completely depict, or to allow us to totally understand the new business scenarios. Today, more than ever, it is necessary to recognize the need for a paradigm shift that can carry science beyond the analytical reductionist approach, and towards a more comprehensive systemic perspective. Systems thinking can be critical to unlock new perspectives and enhance holistic views for a bette…
La partecipazione ad un business ecosystem: implicazioni per la nozione di successo
2020
L’obiettivo del capitolo è offrire un’introduzione alla letteratura sugli ecosistemi aziendali e discutere critica-mente la tematica del successo e della misurazione delle performance del business ecosystem e degli attori che vi partecipano. A tale scopo, il capitolo è strutturato come segue. Il paragrafo 2 focalizza l’attenzione sulla definizione di business ecosystem. I paragrafi 3, 4 e 5 spiegano, rispettivamente, perché nasce un business ecosystem, chi sono gli attori e quali sono le strutture sottese agli ecosistemi aziendali. Il paragrafo 6 discute la misurazione delle performance del business ecosystem focalizzando l’attenzione sui seguenti aspetti: (a) indicatori di performance a li…
C57BL/6-specific conditions for efficient in utero electroporation of the central nervous system.
2014
Abstract Background In utero electroporation is a fast an efficient tool to specifically address gene expression in the murine central nervous system. This technique was originally established in ICR/CD-1 outbred mice. Neuroanatomical differences between the different mouse strains and variations in gestation length require the optimization of the conditions for each strain to avoid severe complications. Furthermore the relevant position information is currently only scarcely standardized and not always easy to transfer to C57BL/6 mice. New method In this study we present an improved method for in utero electroporation of C57BL/6 including a detailed atlas that allows for specific and effic…
TCP Performance in Mobile Ad hoc Networks
2013
International audience; In this paper, we present a survey of TCP (Transmission Control Protocol) protocol for better performance in the MANET (Mobile Ad Hoc Network). After a short presentation of the main features of TCP, we give the most important problems from which TCP suffer in MANET. We present after that some approaches proposed in the literature in order to improve its performance. Our paper contains also a performance evaluation of TCP NewReno and TCP Vegas transport protocols under AODV and DSR routing protocols. The simulations are conducted under varying conditions of number of TCP connections, number of nodes and mobility.
DSC AND TGA TO EVALUATE THE SELECTIVE IMPREGNATION OF WATERLOGGED ARCHAEOLOGICAL WOODS WITH POLY(ETHYLENE) GLYCOLS MIXTURES
2012
Within the cultural heritage field the wood conservation of waterlogged archaeological objects aims at preventing the collapsing of the wooden structure (upon drying) the degradation of which is related to the Taxon but also to the chemical and biological nature of the site. The refilling of the wood cavities with a consolidant, which confers robustness and stability, is an interesting strategy for the conservation methods of waterlogged archaeological objects. To this purpose, using different impregnation methods, waterlogged archaeological woods were consolidated by using aqueous mixtures of poly(ethylene) glycols with different molecular weights (PEG 400 and PEG 4000) as well as mixtures…
Aberrations of Genomic Imprinting in Glioblastoma Formation
2021
In human glioblastoma (GBM), the presence of a small population of cells with stem cell characteristics, the glioma stem cells (GSCs), has been described. These cells have GBM potential and are responsible for the origin of the tumors. However, whether GSCs originate from normal neural stem cells (NSCs) as a consequence of genetic and epigenetic changes and/or dedifferentiation from somatic cells remains to be investigated. Genomic imprinting is an epigenetic marking process that causes genes to be expressed depending on their parental origin. The dysregulation of the imprinting pattern or the loss of genomic imprinting (LOI) have been described in different tumors including GBM, being one …
Stochastic Loss of Silencing of the Imprinted Ndn/NDN Allele, in a Mouse Model and Humans with Prader-Willi Syndrome, Has Functional Consequences
2013
Genomic imprinting is a process that causes genes to be expressed from one allele only according to parental origin, the other allele being silent. Diseases can arise when the normally active alleles are not expressed. In this context, low level of expression of the normally silent alleles has been considered as genetic noise although such expression has never been further studied. Prader-Willi Syndrome (PWS) is a neurodevelopmental disease involving imprinted genes, including NDN, which are only expressed from the paternally inherited allele, with the maternally inherited allele silent. We present the first in-depth study of the low expression of a normally silent imprinted allele, in path…
Divergently Transcribed Overlapping Genes Expressed in Liver and Kidney and Located in the 11p15.5 Imprinted Domain
1998
Human chromosomal band 11p15.5 has been shown to contain genes involved in the development of several pediatric and adult tumors and in Beckwith-Wiedemann syndrome (BWS). Overlapping P1 artificial chromosome clones from this region have been used as templates for genomic sequencing in an effort to identify candidate genes for these disorders. PowerBLAST identified several matches with expressed sequence tags (ESTs) from fetal brain and liver cDNA libraries. Northern blot analysis indicated that two of the genes identified by these ESTs encode transcripts of 1-1.5 kb with predominant expression in fetal and adult liver and kidney. With RT-PCR and RACE, full-length transcripts were isolated f…