Search results for "INCREASE"

showing 10 items of 253 documents

Leveraging and Deleveraging: Pluses and Minuses

2013

Abstract As in physics, leverage is an amplifier. In business, the leverage is amplifying the losses or the gains. In good times, leverage is good, it is busting the gains, it supports economic growth. Companies and governments are using leverage at large scale. In bad times, it is busting the losses. Companies and governments will have to deleverage. This paper aims to present in brief the concepts of leveraging and deleveraging, to explain why companies, banks and governments are using the leverage, and what are the consequences of using it? The high degree of leverage is one cause of a financial crisis and therefore deleveraging is usually following a financial crisis. We will address th…

MacroeconomicsLeverage (finance)Financial stabilityGeneral EngineeringEnergy Engineering and Power TechnologyFinancial crisisLevaragingFinancial systemFinancial crisisMacro levelEconomicsIncreased stressDelevaragingMacroDeleveragingProcedia Economics and Finance
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Retrospective study of the bone morphology in the posterior mandibular region. Evaluation of the prevalence and the degree of lingual concavity and t…

2016

Background In order to choose the appropriate implant size and to prevent complications, an oral surgeon must know the size and shape of the mandible. In the posterior mandibular region, a lingual undercut is often found and could represent a difficulty hard to manage if a lingual or buccal perforation occur. A large series of computed tomography (CT) images of the mandibular first molar was evaluated and the bone morphology, the prevalence and the degree of the lingual concavity in the first molar region were studied. Material and Methods One hundred and fifty-one computed tomography (CT) examinations of patients were retrospectively evaluated to determine anatomical variations in bone mor…

Male0206 medical engineeringPerforation (oil well)Dentistry02 engineering and technologySubmandibular fossaMandibleMandibular first molar03 medical and health sciences0302 clinical medicinestomatognathic systemPrevalenceMedicineHumansGeneral DentistryRetrospective StudiesDental ImplantsBone morphologybusiness.industryResearchDental Implantation EndosseousMandibleMandibular regionRetrospective cohort study030206 dentistry:CIENCIAS MÉDICAS [UNESCO]020601 biomedical engineeringstomatognathic diseasesIncreased riskOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASSurgeryFemaleOral Surgerybusiness
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Imbalance between genomic gain and loss identifies high-risk neuroblastoma patients with worse outcomes

2021

Survival in high-risk neuroblastoma (HR-NB) patients remains poor despite multimodal treatment. We aimed to identify HR-NB patients with worse outcomes by analyzing the genomic instability derived from segmental chromosomal aberrations. We calculated 3 genomic instability indexes for primary tumor SNP array profiles from 127 HR-NB patients: (1) Copy number aberration burden (%gainslength+%losseslength), (2) copy number load (CNL) (%gainslength-%losseslength) and (3) net genomic load (NGL) (%gainsamount-%lossesamount). Tumors were classified according to positive or negative CNL and NGL genomic subtypes. The impact of the genomic instability indexes on overall survival (OS) was assessed with…

Male0301 basic medicineGenome instabilityOncologyCancer ResearchCopy number loadSNPa single nucleotide polymorphism arrayNeuroblastoma0302 clinical medicineHigh risk neuroblastomaSegmental chromosomal aberrationsHR high-riskCNA copy number aberrationTumor biologyCNL copy number loaddNGL decreased net genomic loadlcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogensPrognosisPrimary tumornCNL negative copy number loadGI genomic instabilityHomogeneous030220 oncology & carcinogenesisMNA MYCN-amplificationFemaleHR-NB high-risk neuroblastomaNB neuroblastomaSNP arrayOriginal articlemedicine.medical_specialtyDNA Copy Number VariationsiNGL increased net genomic loadpCNL positive copy number loadhetMNA heterogeneous MYCN-amplificationlcsh:RC254-282Polymorphism Single NucleotideGenomic InstabilityUHR ultra-high-riskOS overall survivalNet genomic load03 medical and health sciencesSCA segmental chromosomal aberrationInternal medicineNeuroblastomamedicineHumansNGL net genomic loadGenetic Predisposition to DiseaseGenomic imbalanceGenetic Association StudiesEFS event-free survivalProportional Hazards ModelsChromosome AberrationsPloidieshomMNA homogeneous MYCN-amplificationProportional hazards modelbusiness.industryGene AmplificationGenetic Variationmedicine.diseasePatient Outcome AssessmentCopy number aberration burden030104 developmental biologybusinessNeoplasia
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Dietary inflammatory index and mortality: a cohort longitudinal study in a Mediterranean area

2020

Background: Higher Dietary Inflammatory Index (DII®) scores are associated with increased morbidity and mortality. However, little is known about the effects of DII on mortality in Mediterranean countries. Therefore, in the present study, we aimed to investigate the potential association between DII scores and overall, cancer and cardiovascular disease (CVD) mortality in people living in a Mediterranean area. Methods: DII scores were calculated using a validated food-frequency questionnaire. DII scores were then categorised into tertiles. Mortality was ascertained via death certificates. The association between DII scores with overall and cause-specific mortality was assessed via a multivar…

Male0301 basic medicinemedicine.medical_specialtyLongitudinal studyMedicine (miscellaneous)030209 endocrinology & metabolismDiseaseDiet Surveys03 medical and health sciencescancer; cardiovascular disease; dietary inflammatory index; mortality0302 clinical medicinecardiovascular diseaseCause of DeathNeoplasmsInternal medicinemedicineHumanscancerLongitudinal StudiesAgedProportional Hazards ModelsInflammation030109 nutrition & dieteticsNutrition and DieteticsMediterranean Regionbusiness.industryHazard ratioConfoundingMiddle AgedmortalityConfidence intervalIncreased riskCardiovascular DiseasesCohortdietary inflammatory indexRegression AnalysisMediterranean areaFemalesense organsDiet HealthybusinessJournal of Human Nutrition and Dietetics
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Perceived Stress and Mild Cognitive Impairment among 32,715 Community-Dwelling Older Adults across Six Low- and Middle-Income Countries

2018

<b><i>Background:</i></b> Perceived stress may be a modifiable risk factor for mild cognitive impairment (MCI) and ultimately dementia, but studies on this topic from low- and middle-income countries (LMICs) are lacking. <b><i>Objective:</i></b> We assessed the association between perceived stress and MCI in six LMICs (China, Ghana, India, Mexico, Russia, and South Africa) using nationally representative data. <b><i>Methods:</i></b> Cross-sectional, community-based data on individuals aged ≥50 years from the World Health Organization’s Study on Global Ageing and Adult Health were analyzed. The definition of MCI was base…

MaleAgingGeriatrics & GerontologyInternational CooperationPerceived Stress ScaleLogistic regressionINCREASECognitionRisk FactorsPrevalencePerceived streProspective cohort studyDepression (differential diagnoses)RISK*CognitionDepressionDEMENTIAConfoundingPerceived stressMiddle AgedDEPRESSION*Risk factorALZHEIMERS-DISEASEFemaleIndependent LivingHEALTHLife Sciences & BiomedicineArticleOddsmedicineDementiaHumansCognitive DysfunctionGLUCOCORTICOIDSRisk factorDeveloping CountriesAgedDECLINEScience & Technologybusiness.industrymedicine.diseaseMODELREDUCTIONCross-Sectional StudiesSocioeconomic Factors*Perceived stressRisk factorGeriatrics and GerontologybusinessStress PsychologicalDemography
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Conflict between co-occurring manipulative parasites? An experimental study of the joint influence of two acanthocephalan parasites on the behaviour …

2000

When two parasite species are manipulators and have different definitive hosts, there is a potential for conflict between them. Selection may then exist for either avoiding hosts infected with conflicting parasites, or for hijacking, i.e. competitive processes to gain control of the intermediate host. The evidence for both phenomena depends largely on the study of the relative competitive abilities of parasites within their common intermediate host. We studied the effects of simultaneous infection by a fish acanthocephalan parasite, Pomphorhynchus laevis, and a bird acanthocephalan parasite, Polymorphus minutus, on the behaviour of their common intermediate host, the amphipod Gammarus pulex…

MaleCompetitive BehaviorParasite increased trophic transmissionBehavior AnimalbiologyEcologyIntermediate hostbiology.organism_classificationStatistics NonparametricAcanthocephalaRandom AllocationGammarus pulexSex FactorsInfectious DiseasesPhotophobiaGammarus roeseliCrustaceaAnimalsParasite hostingHelminthsFemaleAnimal Science and ZoologyParasitologyPomphorhynchus laevisAcanthocephalaParasitology
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Gray value measurement for the evaluation of local alveolar bone density around impacted maxillary canine teeth using cone beam computed tomography

2021

Background To investigate whether any relationship between local alveolar bone density and maxillary canine impaction using gray values from cone beam computed tomography. Material and Methods The cone beam computed tomography images of 151 patients were retrospectively evaluated. Maxillary canine was defined as an impacted tooth when root formation was complete and the patient’s age older than 13 or the other side of the maxillary canine has completely erupted. Similarly, complete eruption was defined as the tooth in its expected occlusion and position. Using the cone beam computed tomography software, the region of interest which was 5 mm2 in area, was placed in the trabecular bone on cro…

MaleCuspidCone beam computed tomographyBone densitydiagnosisBone DensityOcclusionMaxillaHumansMedicineGeneral DentistryUNESCO:CIENCIAS MÉDICASDental alveolusRetrospective StudiesOrthodonticsOral Medicine and Pathologybusiness.industryImpactionImpacted toothResearchTooth ImpactedMaxillary canineIncreased Bone DensityCone-Beam Computed Tomographynonodontogenic cystsOtorhinolaryngologyFemaleoral cavitySurgeryoral pathologybusinessMedicina Oral Patología Oral y Cirugia Bucal
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Higher Free Fatty Acid Uptake in Visceral Than in Abdominal Subcutaneous Fat Tissue in Men

2010

Visceral adipose tissue has been shown to have high lipolytic activity. The aim of this study was to examine whether free fatty acid (FFA) uptake into visceral adipose tissue is enhanced compared to abdominal subcutaneous tissue in vivo. Abdominal adipose tissue FFA uptake was measured using positron emission tomography (PET) and [F-18]-labeled 6-thia-hepta-decanoic acid ([F-18]FTHA) and fat masses using magnetic resonance imaging (MRI) in 18 healthy young adult males. We found that FFA uptake was 30% higher in visceral compared to subcutaneous adipose tissue (0.0025 +/- 0.0018 vs. 0.0020 +/- 0.0016 mu mol/g/min, P = 0.005). Visceral and subcutaneous adipose tissue FFA uptakes were strongly…

MaleEndocrinology Diabetes and MetabolismMedicine (miscellaneous)Adipose tissueWhite adipose tissueFatty Acids NonesterifiedGLUCOSE0302 clinical medicineEndocrinologyReference ValuesIN-VIVOchemistry.chemical_classification0303 health sciencesINSULIN-RESISTANCENutrition and DieteticsFatty AcidsMagnetic Resonance Imagingmedicine.anatomical_structureADIPOSE-TISSUEPROLONGED EXERCISESKELETAL-MUSCLESubcutaneous tissueAdultmedicine.medical_specialtyIntra-Abdominal Fat030209 endocrinology & metabolismIntra-Abdominal FatMETABOLISMYoung Adult03 medical and health sciencesInsulin resistanceInternal medicinemedicineHumansTotal TissueINCREASED PHYSICAL-ACTIVITY030304 developmental biologyBLOOD-FLOWbusiness.industryFatty acidSkeletal muscleBiological Transportmedicine.diseaseSubcutaneous Fat AbdominalEndocrinologychemistryPositron-Emission TomographyRadiopharmaceuticalsbusinessMYOCARDIUMObesity
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Impact of rectal distension on prostate CBCT-based positioning assessed with 6 degrees-of-freedom couch

2018

International audience; Introduction: Prostate requires a daily correction of its 3-dimensional position in relation with rectal distension. In this study, we sought to determine whether rectal distension with respect to the rectal behavior might have an impact on prostate translations and/or rotations during prostate image guided radiation therapy using a 6 degrees-of-freedom (DOF) couch.Methods and materials: We reviewed the data from 39 patients with localized prostate cancer treated with protracted external radiation therapy using a 6 DOF couch. Before each fraction, a kilovoltage cone beam computed tomography (kV-CBCT) scan was performed. The automatic fusion algorithm was set to fuse …

MaleKilovoltage Cone Beam Computed Tomography[SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imagingmedicine.medical_treatment78 GyFailureRectum[SDV.CAN]Life Sciences [q-bio]/Cancer[SDV.IB.MN]Life Sciences [q-bio]/Bioengineering/Nuclear medicineIncreased RiskStandard deviationPatient PositioningTrial030218 nuclear medicine & medical imaging03 medical and health sciencesProstate cancer0302 clinical medicineProstatemedicineHumansRadiology Nuclear Medicine and imagingConformal Radiation-TherapyImage-guided radiation therapyCancerContouringbusiness.industryImage-GuidanceRadiotherapy Planning Computer-AssistedAcute ToxicityProstateRectumProstatic NeoplasmsRadiotherapy DosageExternal-Beam RadiotherapyCone-Beam Computed Tomographymedicine.diseaseRadiation therapymedicine.anatomical_structureOncology030220 oncology & carcinogenesisFeasibility StudiesRadiotherapy Intensity-ModulatedStrategiesbusinessNuclear medicineTomography X-Ray ComputedRadiotherapy Image-Guided
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IgE in patients with glomerulonephritis and minimal-change nephrotic syndrome

1979

Serum levels of IgE were studied in 30 children with minimal-change nephrotic syndrome and 32 children with mesangioproliferative glomerulonephritis during different stages of the disease and treatment. In addition, tissue obtained by renal biopsy was investigated by immunofluorescence histology; no deposits of IgE could be found. The serum IgE levels, however, were increased, particularly in patients with minimal-change nephrotic syndrome. It is concluded that IgE does not play a pathogenic role in the development of the renal disease, but that increased IgE levels are an indication of a disturbance of the immune system.

MaleNephrotic SyndromeAdolescentBiopsyNephrosisFluorescent Antibody TechniqueKidneyImmunoglobulin EGlomerulonephritisBiopsymedicineHumansChildKidneybiologymedicine.diagnostic_testbusiness.industryNephrosis LipoidGlomerulonephritisImmunoglobulin Emedicine.diseaseIncreased IgE levelmedicine.anatomical_structureChild PreschoolPediatrics Perinatology and Child HealthImmunologybiology.proteinFemaleRenal biopsybusinessNephrotic syndromeEuropean Journal of Pediatrics
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