Search results for "INFLUENZA"

El Gran Catharro de 1580 ¿gripe o pertussis?

2005

The gran Catharro (1580) is considered the first influenza epidemic. The analysis of various testimonies of the time may offer some doubts about whether or not it was so; and data strongly support that it was a pertussis epidemic.

A case report of double etiology of ecthyma gangrenosum

2019

Abstract Rationale: Ecthyma gangrenosum is a cutaneous infection, most commonly occurring during sepsis evolution with Pseudomonas aeruginosa on an immunocompromised background. There have been rare case reports in previously healthy children and rarer are the cases with double etiology. Patient concerns: We present the case of a female Caucasian patient, aged 1 year and 8 months, who developed severe sepsis during flu evolution with predominant respiratory and cerebral manifestations. On admission, at skin level, there was noticed a necrotic coccygeal ulceration (with rapid increasing dimensions 0.5/0.5 cm in 24 hours), and with the transformation from a dry necrosis in a sphacelus at the …

2014

Pandemic and seasonal influenza viruses cause considerable morbidity and mortality in the general human population. Protection from severe disease may result from vaccines that activate antigen-presenting DC for effective stimulation of influenza-specific memory T cells. Special attention is paid to vaccine-induced CD8+ T-cell responses, because they are mainly directed against conserved internal influenza proteins thereby presumably mediating cross-protection against circulating seasonal as well as emerging pandemic virus strains. Our study showed that influenza whole virus vaccines of major seasonal A and B strains activated DC more efficiently than those of pandemic swine-origin H1N1 and…

Application of a Bayesian Spatiotemporal Surveillance Method to NYC Syndromic Data

2014

Incorporating prior knowledge (e.g., the spatial distribution of zip codes and background population effects) into a model using Bayesian methods could potentially improve outbreak detection. We adapted a previously described Bayesian model-based spatiotemporal surveillance technique to daily respiratory syndrome counts in NYC Emergency Department data in 2009, the year of the H1N1 influenza pandemic. Citywide, 56 alarms were produced across 15 zip codes, all during days of elevated respiratory visits. Future work includes evaluating our choice of baseline length, considering other alarm thresholds, and conducting a formal evaluation of the method across five syndromes in NYC.

Influenza morfodinamica nei corsi d’acqua naturali: verifiche sperimentali

2000

Becton Dickinson Directigen EZ Flu A+B assay in the diagnosis of pandemic influenza A H1N1 2009 virus infection in adult patients

2011

Viroporins, Examples of the Two-Stage Membrane Protein Folding Model

2015

Viroporins are small, α-helical, hydrophobic virus encoded proteins, engineered to form homo-oligomeric hydrophilic pores in the host membrane. Viroporins participate in multiple steps of the viral life cycle, from entry to budding. As any other membrane protein, viroporins have to find the way to bury their hydrophobic regions into the lipid bilayer. Once within the membrane, the hydrophobic helices of viroporins interact with each other to form higher ordered structures required to correctly perform their porating activities. This two-step process resembles the two-stage model proposed for membrane protein folding by Engelman and Poppot. In this review we use the membrane protein folding …

Effetti delle campagne di vaccinazione attiva contro l'influenza tra il personale dell'Azienda Ospedaliera Universitaria Policlinico

2007

Influenza vaccination among healthcare workers and absenteeism from work due to influenza-like illness in a teaching hospital in Palermo

2012

<p><strong>Background</strong>: Annual flu vaccination of healthcare workers (HCWs) is recommended worldwide as the best way to prevent influenza and to avoid its transmission. However, in several European Countries, vaccination rate among HCWs is still less than 25%. The aim of this study was to determine the HCW vaccination coverage during a three year period in a large University Hospital, identifying socio demographic and occupational variables involved in the decision to accept influenza vaccination. Moreover, for the 2007-2008 season, we also assessed the effectiveness of influenza vaccination in reducing influenza-related absenteeism.</p><p><strong&gt…

The Immunology of Zoonotic Infections

2012

Zoonotic infections are in general defined as infections transmitted from animal to man (and less frequently vice versa), either directly (through contact or contact with animal products) or indirectly (through an intermediate vector as an arthropod or an insect) [1]. Although the burden of zoonotic infections worldwide is major, both in terms of immediate and long-term morbidity and mortality [2, 3] and in terms of emergence/reemergence and socioeconomical, ecological, and political correlations [4], scientific and public health interest and funding for these diseases remain relatively minor. Zoonoses include diseases induced by diverse pathogens (bacteria, viruses, fungi, and parasites), …