Search results for "INFORMATICS"
showing 10 items of 2542 documents
GPCALMA: A Grid-based tool for mammographic screening
2005
The next generation of High Energy Physics (HEP) experiments requires a GRID approach to a distributed computing system and the associated data management: the key concept is the Virtual Organisation (VO), a group of distributed users with a common goal and the will to share their resources. A similar approach is being applied to a group of Hospitals which joined the GPCALMA project (Grid Platform for Computer Assisted Library for MAmmography), which will allow common screening programs for early diagnosis of breast and, in the future, lung cancer. HEP techniques come into play in writing the application code, which makes use of neural networks for the image analysis and proved to be useful…
Activity typologies as a design model for the ubiquitous detection of daily routines
2018
Emerging technologies open up new visions and business potential for systems design and development in the areas of wellbeing and health. New technologies enable the detection of human performance and early changes in physical and cognitive functioning, making it possible to monitor an older person’s wellbeing. This kind of technology or service sets significant requirements for design, as design concepts must be able to capture the complexity of people’s daily lives in terms of activities and environments. Technology itself is “blind” unless designers can adapt it to human life. There is thus a distinct need for comprehensive design and development models that generate adequate human requi…
PROTEIN SECONDARY STRUCTURE PREDICTION: HOW TO IMPROVE ACCURACY BY INTEGRATION
2006
In this paper a technique to improve protein secondary structure prediction is proposed. The approach is based on the idea of combining the results of a set of prediction tools, choosing the most correct parts of each prediction. The correctness of the resulting prediction is measured referring to accuracy parameters used in several editions of CASP. Experimental evaluations validating the proposed approach are also reported.
INVESTIGATION OF BIOTIC STRESS RESPONSES IN FRUIT TREE CROPS USING META-ANALYTICAL TECHNIQUES.
2020
In recent years, RNA sequencing and analysis using Next Generation Sequencing (NGS) methods have enabled to understand the gene expression pertaining to plant biotic and abiotic stress conditions in both quantitative and qualitative manner. The large number of transcriptomic works published in plants requires more meta-analysis studies that would identify common and specific features in relation of the high number of objective studies performed at different developmental and environmental conditions. Meta-analysis of transcriptomic data will identify commonalities and differences between differentially regulated gene lists and will allow screen which genes are key players in gene-gene and p…
INVESTIGATION ON THE GENETIC BASIS OF ENVIRONMENTAL STRESS IN FRUIT TREE CROPS
2021
Plant stress can be divided into two major categories: abiotic stress and biotic stress. Abiotic stress happens when plants are exposed to the environment either physically or chemically. There is an emergency in developing crop varieties that are tolerant to abiotic stresses to ensure food security and safety in the coming years. Multiple abiotic stress like drought, heat, frost at flowering and nutrient deficiency can cause an erratic fruiting behavior or following extreme events, the death of the plants. Plants require an optimal level of nutrients and essential minerals for their growth and development that are mainly acquired from soil by their roots. Nutrient deficiency is an environm…
A high computing bioinformatic approach based on GRID for detecting recombination in whole Citrus Tristeza Virus genome
2007
Implementation of an online information system for the “Flora Critica d’Italia”
2015
Since the early 2000s, within the Italian Botanical Society was discussed the opportunity to realize collaboratively a modern Flora articulated in monographs on the model of others under construction or recently completed in several European countries (1). This initiative had a milestone in 2007 with the institution of the “Fondazione per la Flora Italiana”, with the aim of supporting the activities of study, conservation and cultural and scientific enhancement of the flora of Italy and of sensitizing the national community about the many functions that it implements, in the context of natural and semi-natural ecosystems. The “Foundation for the Italian flora” is responsible for the publica…
New insights of epithelial-to-mesenchymal transition (EMT) signature in breast cancer
2023
Genome wide survey of the Toll-like receptor family in the Mediterranean sea urchin
Toll-like receptors (TLRs) represent a conserved family of proteins widely expressed in eukaryotes. They play crucial roles in the innate immune system recognizing different pathogen-associated molecular patterns. In mammals the TLR family comprises 10-13 members, while a huge number of TLR-like genes were recovered in S.purpuratus[1-3]. The Paracentrotus lividus genome project recently generated a new highquality assembly of the genome that represents a valuable resource also for clarifying the evolutionary origin of immune system. In order to identify TLR genes in P.lividus, a genome wide survey was carried out and BLAT searches retrieved 119 TLR genes (PlivTLRs). Ab initio gene predictio…