Search results for "INR"
showing 10 items of 184 documents
MIS-C in un paziente con AIG sistemica e mutazione di NLRP-3 in terapia con anakinra
2021
IL-1 BLOCKADE IN PAEDIATRIC RECURRENT PERICARDITIS: A MULTICENTRIC RETROSPECTIVE STUDY OF THE ITALIAN COHORT
2019
Introduction: Acute pericarditis is an inflammatory condition causing the occurrence of pericardial effusion. In a third of patients, the disease is recurrent. First line treatment of idiopathic pericarditis consists in non-steroidal anti-inflammatory drugs (NSAIDs) and colchicine; glucocorticoids represent the second line treatment in resistant or intolerant cases. A recent clinical trial has enlightened the effectiveness of anakinra in adults and paediatric patients with colchicine-resistant recurrent pericarditis. Objectives: To describe the clinical characteristics and response to treatment in a cohort of paediatric patients with recurrent pericarditis treated with IL inhibitors. Method…
Tasso di persistenza in terapia di anakinra e canakinumab nelle malattie autoinfiammatorie monogeniche: studio osservazionale dal registro internazio…
2021
First-forbidden transitions in reactor antineutrino spectra
2019
© 2019 American Physical Society. We study the dominant forbidden transitions in the antineutrino spectra of the fission actinides from 4 MeV onward using the nuclear shell model. Through explicit calculation of the shape factor, we show the expected changes in cumulative electron and antineutrino spectra. Relative to the allowed approximation this results in a minor decrease of electron spectra above 4 MeV, whereas an increase of several percent is observed in antineutrino spectra. We show that forbidden transitions dominate the spectral flux for most of the experimentally accessible range. Based on the shell model calculations we attempt a parametrization of forbidden transitions and prop…
New design and simulation of the ion guide for neutron-induced fission products at the IGISOL facility
2023
Measurements of independent fission yield distributions in neutron-induced fission at high neutron energies are important for our fundamental understanding of the fission process, and are also relevant for reactor physics applications. So far, measurements of independent fission yields in proton-induced fission have been performed at the IGISOL facility at the University of Jyväskylä, using the Penning trap as a high resolving-power mass-filter. In order to also facilitate measurements of neutron-induced fission, a dedicated ion guide and a proton-to-neutron converter was developed. However, the first measurement indicates that fewer fission products than expected reach the Penning trap. To…
Steering Institutionalization through Institutional Work: The Case of an eProcurement System in Indonesian Local Government
2014
Corruption is arguably one of the main hindrances to development. In their effort to combat corruption, governments in developing countries turn to information technology to enhance transparency in decision making. However, implementation of an information system in this context is not straightforward. Premised upon institutional theory, this interpretive case study traces the role of institutional actors in the institutionalization of an eProcurement system in Indonesian local government. It draws on different streams of research on institutional work to develop an interpretive lens to understand what institutional actors do to steer the institutionalization process. It identifies a set of…
Conceptualization for intended action: A dynamic model
2023
Concepts are the building blocks of higher-order cognition and consciousness. Building on Conceptual Spaces Theory (CST) and proceeding from the assumption that concepts are inherently dynamic, this paper provides historical context to and significantly elaborates the previously offered Iterative Subdivision Model (ISDM) with the goal of pushing it toward empirical testability. The paper describes how agents in continuous interaction with their environment adopt an intentional orientation, estimate the utility of the concept(s) applicable to action in the current context, engage in practical action, and adopt any new concepts that emerge: a largely pre-intellectual cycle that repeats essent…
Exploring the Link between ICT and Development in the Context of Developing Countries : A Literature Review
2014
Published version of an article in the journal: Electronic Journal of Information Systems in Developing Countries. Also available from the publisher at: http://www.ejisdc.org/ojs2/index.php/ejisdc/article/view/1332. Open Access The article contributes to the ongoing discussion on relating information and communication technology (ICT) to development (D). The quest to relate ICT to D is a topic of open deliberation and critical scrutiny in ICT4D research communities. To enhance the understanding in this regard, we conducted a literature review. The review examines 80 articles to identify various development theories and the role of technologies in the development process. While scanning the …
Understanding ICT in ICT4D : An Affordance Perspective
2017
Understanding the role of ICT for development is at the core of ICT4D research. However, prevailing research in this field most often focuses on access or readiness of a technology, or on the outcomes of the technology use. Less attention has been paid to understand the mechanism of the technology use that leads to the outcomes. The question of why ICT in a development context sometimes work and sometimes does not work still remains a subject of enquiry. To enhance our understanding in this regard, we propose to use the concept of affordances to unfold the “black boxed” nature of ICT. We revisited a case from Kenya to illustrate the application of affordances in a ICT4D context. The finding…
Dark Design Patterns : An End-User Perspective
2020
The number of websites and mobile applications available is growing continually, as are the persuasive approaches to influence human behavior and decision making. Although designing for persuasion offers several potential benefits, recent developments expose various deceptive designs, that is, dark patterns, that utilize psychological factors to nudge people toward, from someone else’s perspective, desired directions. This paper contributes to an increased awareness of the phenomenon of dark patterns through our exploring how users perceive and experience these patterns. Hence, we chose a qualitative research approach, with focus groups and interviews, for our exploration. Our analysis show…