Search results for "INTERVENTION"
showing 10 items of 3041 documents
Re-build landscape. Design for the reuse of abandoned quarries
2021
Looking at the history of our geological and mining heritage, we can see the evolution of the role played by underground mining sites over the centuries. However, if the activity of quarrying stones is as old as the presence of humans on earth, the issue of the territorial regeneration, based on the recovery and re-functionalization of abandoned quarries, is one of the central arguments of the contemporary debate. The extractive activity that on one hand constitutes an important economic resource for numerous territories, on the other hand requires particular attention to the environmental impact it causes. The theme is that of the so-called drosscapes, soils and residual spaces, once margi…
Positive Communities: Dimensions for Assessment and Intervention
2014
This chapter presents the construction of dimensions to assess people’s satisfaction with life in the community and makes a proposal to identify positive communities for future assessments. In the first place, this chapter provides a definition of the concepts related to a positive community and additionally, identifies the elements which people value in community life. Satisfaction with life in the community implies a personal perception of the degree of satisfaction in relation with different aspects of community life: community equipment, social services (health, education), public policies, public transportation, safety on the streets and in public places, housing, employment opportunit…
Breaking Stereotypes Concerning Remigrated Children - A Multinational Possible Intervention Plan through School
2021
The article is based on a multinational study involving five countries (Romania, Portugal, Italy, North Macedonia, and Iceland) facing the return migration or remigration situation. Pupils (n = 1615), teachers (n = 370), future teachers (n = 166) and youth workers (n = 30) were questioned about various aspects regarding the subject. Among the matters, cultural needs appear to the most important. Based on the statistical analysis, the article describes the dynamics of the dependent variables, with highlighted interest on cultural needs. Psychological and social needs, cultural needs, and educational needs are discussed and link conclusions appear. Following the analysis, an intervention plan…
Endothelin-1-Mediated Drug Resistance in EGFR-Mutant Non-Small Cell Lung Carcinoma.
2020
Abstract Progression on therapy in non-small cell lung carcinoma (NSCLC) is often evaluated radiographically, however, image-based evaluation of said therapies may not distinguish disease progression due to intrinsic tumor drug resistance or inefficient tumor penetration of the drugs. Here we report that the inhibition of mutated EGFR promotes the secretion of a potent vasoconstrictor, endothelin-1 (EDN1), which continues to increase as the cells become resistant with a mesenchymal phenotype. As EDN1 and its receptor (EDNR) is linked to cancer progression, EDNR-antagonists have been evaluated in several clinical trials with disappointing results. These trials were based on a hypothesis that…
Capillary enlargement, not sprouting angiogenesis, determines beneficial therapeutic effects and side effects of angiogenic gene therapy.
2010
Aims Currently, it is still unclear which mechanisms drive metabolic benefits after angiogenic gene therapy. The side-effect profile of efficient angiogenic gene therapy is also currently incompletely understood. In this study, the effects of increasing doses of adenoviral (Ad) vascular endothelial growth factor-A (VEGF-A) were evaluated on vascular growth, metabolic benefits, and systemic side effects. Methods and results Adenoviral vascular endothelial growth factor-A or AdLacZ control was injected intramuscularly (109–1011 vp/mL) or intra-arterially (5 × 1011 vp/mL) into rabbit ( n = 102) hindlimb muscles and examined 6 or 14 days later. Blood flow, tissue oedema, metabolic benefits, and…
The effects of a 2-year physical activity and dietary intervention on plasma lipid concentrations in children: the PANIC Study
2020
Funder: Opetus- ja Kulttuuriministeriö; doi: http://dx.doi.org/10.13039/501100003126
La eficacia de una intervención con aplicación móvil sobre actitudes asociadas a la violencia de pareja en los adolescentes de centros de acogida
2020
ABSTRACT This study focuses on the effectiveness of an app-based, monitored intervention using the Liad@s app in a residential youth-care setting. The aim of this intervention is to reduce maladaptive beliefs and attitudes linked to dating violence: distortions or myths about romantic love and hostile and benevolent dimensions of sexism. A quasi-experimental pre-post study with a control group was carried out. Participants were 71 adolescents from 9 group homes in Valencia (Spain). The outcomes measures were hostile and benevolent sexism (Ambivalent Sexism Inventory - ASI), ambivalence and prejudice towards men (Ambivalence toward Men Inventory - AMI), and myths about romantic love. The res…
Mental health and psychosocial support strategies in highly contagious emerging disease outbreaks of substantial public concern: A systematic scoping…
2021
Background Acute disease outbreaks such as the COVID-19 pandemic cause a high burden of psychological distress in people worldwide. Interventions to enable people to better cope with such distress should be based on the best available evidence. We therefore performed a scoping review to systematically identify and summarize the available literature of interventions that target the distress of people in the face of highly contagious disease outbreaks. Methods MEDLINE, Cochrane CENTRAL, Web of Science (January 2000 to May 7, 2020), and reference lists were systematically searched and screened by two independent reviewers. Quantitative and qualitative studies investigating the effects of psyc…
The role of practitioners in helping persons make effective use of information and communication technology in career interventions
2019
We examine the role of counselors and other practitioners in delivering career interventions using Information and Communication Technology (ICT). Current benefits and limitations of ICT use provide the basis for recommendations. Potential benefits of increased ICT engagement include cost-effectiveness and improved access to resources and support. Potential limitations include poor assessment and information quality, limited practitioner support when needed, problems with distance intervention and social media, confidentiality of client records, inequality of access, inadequate competencies, and poor implementation. Specific practitioner roles are identified, and those related to social med…
Correlations between Reading Disabilities and Learning Disabilities
2015
The article is devoted to reveal correlations between reading disabilities and learning disabilities. These problems need to be explained and teachers need to have reasonable solutions. Number of school-children with learning disabilities is increasing and teacher is not able to find the best and most precise ways of diagnostics and treatment/intervention. Causes of learning disabilities are different: brain damage or distorted functioning of it; auditory or visual perception and operating problems; language acquisition or processing problems etc. Symptoms are mostly noticed in the main areas – reading, writing and mathematics. Reading disabilities are one of the most obvious and serious pr…