Search results for "INVERTEBRATES"

showing 10 items of 230 documents

Inducing Cold-Sensitivity in the Frigophilic Fly Drosophila montana by RNAi.

2016

Cold acclimation is a critical physiological adaptation for coping with seasonal cold. By increasing their cold tolerance individuals can remain active for longer at the onset of winter and can recover more quickly from a cold shock. In insects, despite many physiological studies, little is known about the genetic basis of cold acclimation. Recently, transcriptomic analyses in Drosophila virilis and D. montana revealed candidate genes for cold acclimation by identifying genes upregulated during exposure to cold. Here, we test the role of myo-inositol-1-phosphate synthase (Inos), in cold tolerance in D. montana using an RNAi approach. D. montana has a circumpolar distribution and overwinters…

CartographyEvolutionary GeneticsArthropodaDeath RatesAcclimatizationGene ExpressionArtificial Gene Amplification and ExtensionInsect PhysiologyResearch and Analysis MethodsBiochemistryPolymerase Chain ReactionExtreme Cold WeatherRNA interferenceModel OrganismsPopulation MetricsGeneticsAnimalsAnimal PhysiologyMolecular Biology TechniquesMolecular BiologyDemographyInvertebrate PhysiologyEvolutionary BiologyLatitudePopulation BiologyGeographyGene Expression ProfilingDrosophila MelanogasterfungiOrganismsBiology and Life SciencesAnimal ModelsInvertebratesCold TemperatureNucleic acidsInsectsGene Expression RegulationGenetic interferencePeople and PlacesEarth SciencesRNADrosophilaFemaleMyo-Inositol-1-Phosphate SynthaseEpigeneticsZoologyEntomologyResearch ArticlePloS one
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Two Enhancers Control Transcription of Drosophila muscleblind in the Embryonic Somatic Musculature and in the Central Nervous System

2014

The phylogenetically conserved family of Muscleblind proteins are RNA-binding factors involved in a variety of gene expression processes including alternative splicing regulation, RNA stability and subcellular localization, and miRNA biogenesis, which typically contribute to cell-type specific differentiation. In humans, sequestration of Muscleblind-like proteins MBNL1 and MBNL2 has been implicated in degenerative disorders, particularly expansion diseases such as myotonic dystrophy type 1 and 2. Drosophila muscleblind was previously shown to be expressed in embryonic somatic and visceral muscle subtypes, and in the central nervous system, and to depend on Mef2 for transcriptional activatio…

Central Nervous SystemTranscription Geneticlcsh:MedicineEnhancer RNAsMechanical Treatment of SpecimensExonGenes ReporterMolecular Cell BiologyMorphogenesisPattern Formationlcsh:SciencePromoter Regions GeneticConserved SequenceGeneticsRegulation of gene expressionMultidisciplinaryMusclesDrosophila MelanogasterGene Expression Regulation DevelopmentalRNA-Binding ProteinsCell DifferentiationGenomicsAnimal ModelsInsectsEnhancer Elements GeneticElectroporationSpecimen DisruptionOrgan SpecificityRegulatory sequenceDrosophilaResearch ArticleMef2ArthropodaMolecular Sequence DataDNA transcriptionBiologyResearch and Analysis MethodsGenètica molecularModel OrganismsGeneticsAnimalsHumansEnhancerTranscription factorBase SequenceBiology and life scienceslcsh:ROrganismsPromoterCell BiologyInvertebratesSpecimen Preparation and Treatmentlcsh:QGene expressionAnimal GeneticsDevelopmental BiologyNeurosciencePLoS ONE
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Mercury and chlorinated hydrocarbons in zoobenthos of Lake Päijänne, Finland

1979

The average amounts of mercury, PCBs, and sigma DDT (primarily DDE), found in macrozoobenthos, on the wet basis, in Lake Päijänne, Finland, for the time period 1972-1974, were 79 ng/g, 29 ng/g, and 8 ng/g, respectively. Lindane was found in negligible amounts in only 2% of the samples examined; aldrin was present in 10% of the samples; no dieldrin was detected. Mercury and PCB concentrations varied regionally in the lake. PCB and sigma DDT concentrations were greater in the predatory bottom animals than in the herbivores or detritus feeders, and the amounts of chlorinated hydrocarbons were greater in profundal animals than in littoral animals. No significant correlation was apparent between…

ChemistryHealth Toxicology and MutagenesisDetritivorechemistry.chemical_elementFresh WaterMercuryGeneral MedicineToxicologyInvertebratesPolychlorinated BiphenylsPollutionDDTMercury (element)chemistry.chemical_compoundDieldrinEnvironmental chemistryHydrocarbons ChlorinatedLittoral zoneAnimalsEcotoxicologyAldrinProfundal zoneLindaneFinlandArchives of Environmental Contamination and Toxicology
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Catastrophic effects of sand mining on macroinvertebrates in a large shallow lake with implications for management

2019

Sand mining is a human activity that is increasing in inland waters and has profound effects on entire aquatic ecosystems. However, current knowledge of the effects of sand mining on freshwater lake ecosystems remains limited, especially for biotic communities. Here, we investigated the responses of macroinvertebrates to indiscriminate sand mining in a large shallow lake of China. Our results indicated that sand mining significantly increased the content of suspended particulate matter, total nitrogen, total phosphorus and chlorophyll a in the water column both in the sand mining area and the area adjacent to the dredging activities. While there was significantly lower total nitrogen and th…

ChinaEnvironmental Engineering010504 meteorology & atmospheric sciencessand dredging010501 environmental sciencesmacroinvertebrate01 natural sciencesMiningSphaeriumDredgingWater columnparasitic diseasesEnvironmental ChemistryAnimalsWaste Management and DisposalEcosystem0105 earth and related environmental sciencesSand miningBiomass (ecology)biologykaivostoimintaEcologyAquatic ecosystemLake ecosystemvesiekosysteemitympäristönsuojeluBiodiversityselkärangattomatbiology.organism_classificationPollutionInvertebratesbiological traitsbiodiversiteettiekosysteemit (ekologia)LakesBenthic zonebiomonitoringEnvironmental scienceEnvironmental Monitoring
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A battery of toxicity tests as indicators of decontamination in composting oily waste.

2000

Heterogeneous oily waste from an old dumping site was composted in three windrows constructed from different proportions of waste, sewage sludge, and bark. The objectives of this pilot study were to examine the usefulness of composting as a treatment method for this particular waste and to study decontamination in the composting process by using a battery of toxicity tests. Five samples from the windrow having intermediate oil concentrations were tested with toxicity tests based on microbes (Pseudomonas putida growth inhibition test, ToxiChromotest, MetPLATE, and three different modifications of a luminescent bacterial test), enzyme inhibition (reverse electron transport), plants (duckweed …

ChlorophyllHealth Toxicology and MutagenesisPlant DevelopmentGerminationcomplex mixturesWindrowBioremediationPseudomonasEscherichia coliBioassayAnimalsSoil PollutantsDecontaminationSewage sludgeOrganellesPlants MedicinalEnchytraeusbiologyChemistryPublic Health Environmental and Occupational HealthFabaceaeGeneral MedicineHuman decontaminationPlantsbiology.organism_classificationPollutionInvertebratesWaste treatmentPetroleumMetalsEnvironmental chemistryToxicityLuminescent MeasurementsColorimetryDNA DamageEcotoxicology and environmental safety
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The Mucus of Actinia equina (Anthozoa, Cnidaria): An Unexplored Resource for Potential Applicative Purposes

2015

The mucus produced by many marine organisms is a complex mixture of proteins and polysaccharides forming a weak watery gel. It is essential for vital processes including locomotion, navigation, structural support, heterotrophic feeding and defence against a multitude of environmental stresses, predators, parasites, and pathogens. In the present study we focused on mucus produced by a benthic cnidarian, the sea anemone Actinia equina (Linnaeus, 1758) for preventing burial by excess sedimentation and for protection. We investigated some of the physico-chemical properties of this matrix such as viscosity, osmolarity, electrical conductivity, protein, carbohydrate, and total lipid contents. Som…

CnidariaErythrocytesCarbohydratesPharmaceutical ScienceSea anemonePolysaccharideActinia equina; Antibacterial activity; Cytotoxicity; Hemolytic activity; Mucus; Tumor cell line K562; Drug Discovery3003 Pharmaceutical ScienceArticleActinia equinaBiological FactorsCnidarian Venomsantibacterial activityDry weightCell Line TumorAnthozoaDrug DiscoveryAnimalsHumanshemolytic activitylcsh:QH301-705.5Pharmacology Toxicology and Pharmaceutics (miscellaneous)chemistry.chemical_classification<i>Actinia equina</i>tumor cell line K562biologyCytotoxinsHemolytic AgentsEcologyDrug Discovery3003 Pharmaceutical SciencemucuAnthozoabiology.organism_classificationInvertebratesMucusAnti-Bacterial AgentsMucusSea Anemoneslcsh:Biology (General)chemistryBiochemistryMucucytotoxicityRabbitsK562 CellsAntibacterial activityActiniaMarine Drugs
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Taxonomic flux as a measure of evolutionary turnover

2021

We introduce a new metric, "taxonomic flux", to quantify evolutionary trends both within and across taxonomic boundaries. This metric is normalized, which reduces the effect of sample size disparity between biologic groups and time intervals. Furthermore, this methodology considers stratigraphic range data as a whole, and measures relative growth or decline of diversity values as they deviate from system stability. Such trends may yield key information relating to evolutionary processes and forcing functions, especially if these trends are correlative within particular taxa or niche occupancy. Thus far, scientists and researchers have been stymied by absolute values derived from unequal dat…

CorrelativeTaxonForcing (recursion theory)OccupancyRange (biology)Metric (mathematics)Nichecenozoic biodiversity metrics invertebrates stasis volatility.EconometricsPaleontologyEvolutionary dynamicsQE701-760MathematicsSpanish Journal of Palaeontology
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Influence of Temperature, Hypercapnia, and Development on the Relative Expression of Different Hemocyanin Isoforms in the Common CuttlefishSepia offi…

2012

The cuttlefish Sepia officinalis expresses several hemocyanin isoforms with potentially different pH optima, indicating their reliance on efficient pH regulation in the blood. Ongoing ocean warming and acidification could influence the oxygen-binding properties of respiratory pigments in ectothermic marine invertebrates. This study examined whether S. officinalis differentially expresses individual hemocyanin isoforms to maintain optimal oxygen transport during development and acclimation to elevated seawater pCO2 and temperature. Using quantitative PCR, we measured relative mRNA expression levels of three different hemocyanin isoforms in several ontogenetic stages (embryos, hatchlings, juv…

Cuttlefish0303 health sciencesPhysiologyEcology030310 physiologyOntogenymedicine.medical_treatmentOxygen transportHemocyaninMarine invertebratesBiologybiology.organism_classificationCephalopod03 medical and health sciencesBiochemistryHemolymphGeneticsmedicineAnimal Science and Zoology14. Life underwaterSepiaMolecular BiologyEcology Evolution Behavior and Systematics030304 developmental biologyJournal of Experimental Zoology Part A: Ecological Genetics and Physiology
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Identification and Expression of the SOS Response, aidB-Like, Gene in the Marine Sponge Geodia cydonium: Implication for the Phylogenetic Relationshi…

1998

Sponges (Porifera) are the phylogenetically oldest metazoan organisms. From one member of the siliceous sponges, Geodia cydonium, the cDNA encoding a putative SOS protein, the AidB-like protein of the Ada system from bacteria, was isolated and characterized. The cDNA, GCaidB, comprises an open reading frame of 446 amino acid (aa) residues encoding a polypeptide with a calculated Mr of 49,335. This molecule shows high similarity to the bacterial AidB proteins from Mycobacterium tuberculosis and Escherichia coli and somewhat lower similarities to acyl-CoA dehydrogenases (ADHs) and acyl-CoA oxidases (AOXs). Northern blot analysis confirmed the presence of the complete transcript. The deduced s…

DNA ComplementarySequence analysisMolecular Sequence DataSequence alignmentBiologymedicine.disease_causeAcyl-CoA DehydrogenaseEvolution MolecularBacterial ProteinsPhylogeneticsComplementary DNAGeneticsmedicineAnimalsAmino Acid SequenceSOS Response GeneticsMolecular BiologyGeneEscherichia coliPeptide sequencePhylogenyEcology Evolution Behavior and SystematicsGeneticsBase SequenceEscherichia coli ProteinsAcyl-CoA Dehydrogenase Long-ChainSequence Analysis DNABlotting NorthernInvertebratesPoriferaOpen reading frameBiochemistryOxidoreductasesSequence AlignmentJournal of Molecular Evolution
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Manipulating mtDNA in vivo reprograms metabolism via novel response mechanisms.

2019

Mitochondria have been increasingly recognized as a central regulatory nexus for multiple metabolic pathways, in addition to ATP production via oxidative phosphorylation (OXPHOS). Here we show that inducing mitochondrial DNA (mtDNA) stress in Drosophila using a mitochondrially-targeted Type I restriction endonuclease (mtEcoBI) results in unexpected metabolic reprogramming in adult flies, distinct from effects on OXPHOS. Carbohydrate utilization was repressed, with catabolism shifted towards lipid oxidation, accompanied by elevated serine synthesis. Cleavage and translocation, the two modes of mtEcoBI action, repressed carbohydrate rmetabolism via two different mechanisms. DNA cleavage activ…

DYNAMICSLife CyclesSTRESSMITOCHONDRIAL-DNAADN mitocondrialQH426-470BiochemistryOxidative PhosphorylationLarvaeAdenosine TriphosphateTRANSCRIPTIONPost-Translational ModificationEnergy-Producing OrganellesProtein MetabolismOrganic CompoundsDrosophila MelanogasterChemical ReactionsMETHYLATIONEukaryotaAcetylationAnimal ModelsDNA Restriction EnzymesKetonesCellular ReprogrammingMitochondrial DNAMitochondriaTRANSLOCATIONNucleic acidsInsectsChemistryDROSOPHILAExperimental Organism SystemsPhysical SciencesSURVIVALCarbohydrate MetabolismCellular Structures and OrganellesMetabolic Networks and PathwaysResearch ArticlePyruvateArthropodaForms of DNAeducationCarbohydratesBioenergeticsResearch and Analysis MethodsDNA MitochondrialBiokemia solu- ja molekyylibiologia - Biochemistry cell and molecular biologyModel OrganismsGenetiikka kehitysbiologia fysiologia - Genetics developmental biology physiologyGeneticsAnimalsHumansBiology and life sciencesOrganic ChemistryOrganismsChemical CompoundsProteinsDNACell BiologyInvertebratesDELETIONSOxidative StressMetabolismMAINTENANCEDiabetes Mellitus Type 2Animal Studies1182 Biochemistry cell and molecular biologyAcidsDevelopmental BiologyPLoS Genetics
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