Search results for "IOS"

showing 10 items of 8115 documents

Enhancing heterologous protein expression and secretion in HEK293 cells by means of combination of CMV promoter and IFNα2 signal peptide

2016

Efficient production and secretion of recombinant proteins in mammalian cell lines relies in a combination of genetic, metabolic and culture strategy factors. The present work assesses the influence of two key genetic components of expression vectors (promoter and signal peptide) on protein production and secretion effciency in HEK293 cells expressing eGFP as a reporter protein. Firstly, the strength of 3 different promoters was evaluated using transient expression methods. Flow cytometry analysis revealed that the highest level of intracellular protein expression was found when eGFP was under the control of CMV promoter, being 3-times higher in comparison to the rest of the promoters teste…

0106 biological sciences0301 basic medicineSignal peptideGreen Fluorescent ProteinsCytomegalovirusHeterologousBioengineeringProtein Sorting SignalsBiology01 natural sciencesApplied Microbiology and BiotechnologyGreen fluorescent protein03 medical and health sciences010608 biotechnologyProtein biosynthesisHumansSecretionPromoter Regions GeneticExpression vectorInterferon-alphaPromoterGeneral MedicineMolecular biologyRecombinant ProteinsHEK293 Cells030104 developmental biologyCell cultureBiotechnologyJournal of Biotechnology
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Contrasting biogeographical patterns in Margarella (Gastropoda: Calliostomatidae: Margarellinae) across the Antarctic Polar Front

2021

International audience; Members of the trochoidean genus Margarella (Calliostomatidae) are broadly distributed across Antarctic and sub-Antarctic ecosystems. Here we used novel mitochondrial and nuclear gene sequences to clarify species boundaries and phylogenetic relationships among seven nominal species distributed on either side of the Antarctic Polar Front (APF). Molecular reconstructions and species-delimitation analyses recognized only four species: M. antarctica (the Antarctic Peninsula), M. achilles (endemic to South Georgia), M. steineni (South Georgia and Crozet Island) and the morphologically variable M. violacea (=M. expansa, M. porcellana and M. pruinosa), with populations in s…

0106 biological sciences0301 basic medicineTime FactorsAntarctic Polar FrontGastropodalong-distance dispersalAntarctic RegionsBiology010603 evolutionary biology01 natural sciencesDNA MitochondrialPorcellanaCalliostomatidae03 medical and health sciencesSpecies SpecificityGastropodaGeneticsAnimals14. Life underwaterGlacial periodMargarellaSouthern OceanMolecular BiologyEcology Evolution Behavior and SystematicsPhylogenyPolar frontGenetic diversityPolymorphism GeneticEcologyBayes TheoremDNA15. Life on landSouth Americabiology.organism_classificationbenthic-protected developmentraftingPhylogeographyMESH: Océan Austral front polaire antarctique dispersion à longue distance développement protégé benthique incubation rafting Margarella030104 developmental biologyBiological dispersalTaxonomy (biology)[SDE.BE]Environmental Sciences/Biodiversity and Ecology
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Trichoderma harzianum Strain T22 Modulates Direct Defense of Tomato Plants in Response to Nezara viridula Feeding Activity

2021

AbstractPlant growth-promoting fungi belonging to genus Trichoderma are known to help plants when dealing with biotic stressors by enhancing plant defenses. While beneficial effects of Trichoderma spp. against plant pathogens have long been documented, fewer studies have investigated their effect on insect pests. Here, we studied the impact of Trichoderma root colonization on the plant defense responses against stink bug feeding attack. For this purpose, a model system consisting of tomato plant, Solanum lycopersicum cv Dwarf San Marzano, Trichoderma harzianum strain T22 and the southern green stink bug, Nezara viridula, was used. We firstly determined stink bug performance in terms of rela…

0106 biological sciences0301 basic medicineTime FactorsTranscription GeneticGreen stink bugBeneficial soil microbes Jasmonic acid signaling pathway Pentatomidae Solanum lycopersicum Stink bugsCyclopentanesGenes PlantPlant Roots01 natural sciencesBiochemistryArticleHeteroptera03 medical and health scienceschemistry.chemical_compoundSolanum lycopersicumGene Expression Regulation PlantPentatomidaePlant defense against herbivoryAnimalsHerbivoryOxylipinsSymbiosisStink bugsEcology Evolution Behavior and SystematicsbiologyBeneficial soil microbesJasmonic acidfungifood and beveragesTrichoderma harzianumGeneral MedicinePentatomidaebiology.organism_classificationHorticulture030104 developmental biologychemistryNezara viridulaJasmonic acid signaling pathwayTrichodermaHypocrealesSeedsFemaleSolanumSignal Transduction010606 plant biology & botany
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Formally described species woefully underrepresent phylogenetic diversity in the common lichen photobiont genus Trebouxia (Trebouxiophyceae, Chloroph…

2020

Lichens provide valuable systems for studying symbiotic interactions. In lichens, these interactions are frequently described in terms of availability, selectivity and specificity of the mycobionts and photobionts towards one another. The lichen-forming, green algal genus Trebouxia Puymaly is among the most widespread photobiont, associating with a broad range of lichen-forming fungi. To date, 29 species have been described, but studies consistently indicate that the vast majority of species-level lineages still lack formal description, and new, previously unrecognized lineages are frequently reported. To reappraise the diversity and the evolutionary relationships of species-level lineages …

0106 biological sciences0301 basic medicineTrebouxiaAlgaeLichensLichenBiologyHolobiont010603 evolutionary biology01 natural sciences03 medical and health sciencesstomatognathic systemSpecies SpecificityPhylogeneticsChlorophytaSpecies delimitationGeneticsAlgae; Biodiversity; Fungi; Holobiont; Multigene; Species delimitation; Symbiosis; Chlorophyta; Genetic Loci; Lichens; Species Specificity; Biodiversity; PhylogenySymbiosisLichenMolecular BiologyEcology Evolution Behavior and SystematicsPhylogenyGenetic diversityintegumentary systemTrebouxiophyceaeFungiBiodiversitybiology.organism_classificationHolobiontstomatognathic diseasesPhylogenetic diversity030104 developmental biologyEvolutionary biologyGenetic LociMultigeneTaxonomy (biology)SymbiosiMolecular phylogenetics and evolution
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Symbiotic polydnavirus and venom reveal parasitoid to its hyperparasitoids

2018

Symbiotic relationships benefit organisms in utilization of new niches. In parasitoid wasps, symbiotic viruses and venom that are injected together with wasp eggs into the host caterpillar suppress immune responses of the host and enhance parasitoid survival. We found that the virus also has negative effects on offspring survival when placing these interactions in a community context. The virus and venom drive a chain of interactions that includes the herbivore and its food plant and attracts the hyperparasitoid enemies of the parasitoid. Our results shed new light on the importance of symbionts associated with their host in driving ecological interactions and highlight the intricacy of how…

0106 biological sciences0301 basic medicineWasps01 natural sciencesMultitrophic interactionParasitoidHerbivore-induced plant volatilesGene Expression Regulation PlantLaboratory of EntomologyTrophic levelPlant-mediatedLarvaMultidisciplinarybiologyPolydnavirusHerbivore-induced plant volatilePlantsBiological SciencesWaspPE&RCOrganische ChemieBiosystematiekInteraction networkinternationalLarvaSymbiosiButterfliesZoology010603 evolutionary biologyHost-Parasite Interactions03 medical and health sciencesMultitrophic interactionsSymbiosisButterflieAnimalsSymbiosisCaterpillarSalivaEcosystemHerbivoreParasitic waspVenomsHost (biology)AnimalOrganic ChemistryfungiPlantLaboratorium voor Entomologiebiology.organism_classificationVenom030104 developmental biologySettore AGR/11 - Entomologia Generale E ApplicataPolydnaviridaeHerbivoreBiosystematicsEPS
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Gut microbiota of the pine weevil degrades conifer diterpenes and increases insect fitness

2017

AbstractThe pine weevil (Hylobius abietis), a major pest of conifer forests throughout Europe, feeds on the bark and cambium, tissues rich in terpenoid resins that are toxic to many insect herbivores. Here we report the ability of the pine weevil gut microbiota to degrade the diterpene acids of Norway spruce. The diterpene acid levels present in ingested bark were substantially reduced on passage through the pine weevil gut. This reduction was significantly less upon antibiotic treatment, and supplementing the diet with gut suspensions from untreated insects restored the ability to degrade diterpenes. In addition, cultured bacteria isolated from pine weevil guts were shown to degrade a Norw…

0106 biological sciences0301 basic medicineZoologyGut floracomplex mixtures010603 evolutionary biology01 natural sciences03 medical and health scienceschemistry.chemical_compoundSymbiosisBotanyGeneticsAnimalsHylobius abietisPiceaEcology Evolution Behavior and SystematicsbiologyHost (biology)Weevilfungibiology.organism_classificationGastrointestinal MicrobiomeEurope030104 developmental biologychemistryvisual_artvisual_art.visual_art_mediumWeevilsBarkGenetic FitnessDiterpenesDiterpeneBacteriaMolecular Ecology
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Take a Trip Through the Plant and Fungal Transportome of Mycorrhiza

2016

International audience; Soil nutrient acquisition and exchanges through symbiotic plant–fungus interactions in the rhizosphere are key features for the current agricultural and environmental challenges. Improved crop yield and plant mineral nutrition through a fungal symbiont has been widely described. In return, the host plant supplies carbon substrates to its fungal partner. We review here recent progress on molecular players of membrane transport involved in nutritional exchanges between mycorrhizal plants and fungi. We cover the transportome, from the transport proteins involved in sugar fluxes from plants towards fungi, to the uptake from the soil and exchange of nitrogen, phosphate, p…

0106 biological sciences0301 basic medicine[ SDV.BV ] Life Sciences [q-bio]/Vegetal BiologySoil nutrientsmembrane transportmycorrhizal transportomePlant Science01 natural sciences03 medical and health sciencesSymbiosissymbiotic plant–fungusMycorrhizaeBotany[SDV.BV]Life Sciences [q-bio]/Vegetal BiologyMycorrhizaplant mineral nutritionSugarSymbiosis2. Zero hungerRhizospherebiologybusiness.industryCrop yieldfungimycorrhizal plants and fungiMembrane Transport Proteinsfood and beveragesBiological Transportnew agro-ecological systems15. Life on landPlantsbiology.organism_classificationKey features030104 developmental biologyAgronomyAgriculturebusinessImproved crop yield010606 plant biology & botany
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Reaction norms of host immunity, host fitness and parasite performance in a mouse - intestinal nematode interaction.

2016

8 pages; International audience; The outcome of the encounter between a host and a parasite depends on the synergistic effects of the genetics of the two partners and the environment (sensulato) where the interaction takes place. Reaction norms can depict how host and parasite traits vary across environmental ranges for different genotypes. Here, we performed a large scale experiment where three strains of laboratory mice (SJL, BALB/c and CBA) were infected with four doses of the intestinal nematode Heligmosomoides polygyrus. An increasing infective dose can be considered as a proxy for the environment-dependent risk incontracting the infection. We looked at the fitness traits of hosts and …

0106 biological sciences0301 basic medicine[ SDV.MP.PAR ] Life Sciences [q-bio]/Microbiology and Parasitology/ParasitologyResistanceHeligmosomoides polygyrusBiologyPlant disease resistance010603 evolutionary biology01 natural sciencesHost-Parasite Interactions03 medical and health sciencesImmune systemImmunityGenotypeFitness[ SDV.EE.IEO ] Life Sciences [q-bio]/Ecology environment/SymbiosisAnimalsParasite hosting[SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/ParasitologyIntestinal Diseases ParasiticDisease ResistanceStrongylida InfectionsMice Inbred BALB CNematospiroides dubiusMus musculus domesticus[ SDE.BE ] Environmental Sciences/Biodiversity and EcologyImmunitybiology.organism_classificationInterleukin 10030104 developmental biologyInfectious DiseasesParasitologySusceptibilityImmunologyMice Inbred CBACytokinesFemaleParasitologyHeligmosomoides polygyrus[SDE.BE]Environmental Sciences/Biodiversity and EcologyReaction normsTolerance[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/Symbiosis
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Updated pest categorisation of Xylella fastidiosa

2018

Abstract Following a request from the European Commission, the EFSA Plant Health Panel updated its pest categorisation of Xylella fastidiosa, previously delivered as part of the pest risk assessment published in 2015. X. fastidiosa is a Gram‐negative bacterium, responsible for various plant diseases, including Pierce's disease, phony peach disease, citrus variegated chlorosis, olive quick decline syndrome, almond leaf scorch and various other leaf scorch diseases. The pathogen is endemic in the Americas and is present in Iran. In the EU, it is reported in southern Apulia in Italy, on the island of Corsica and in the Provence‐Alpes‐Côte d'Azur region in France, as well as in the Autonomous r…

0106 biological sciences0301 basic medicine[SDV]Life Sciences [q-bio]Plant Science01 natural scienceslaw.inventionplant pestlawolive quick decline syndromePierce's diseaseolive quick.media_common2. Zero hungerpest riskquarantinefood and beverages3. Good healthHorticulturecitrus variegated chlorosis; European Union; leaf scorch; olive quick decline syndrome; pest risk; Pierce's disease; plant health; plant pest; quarantineSettore AGR/12 - PATOLOGIA VEGETALEWoody plantSciences exactes et naturellesPierce’s diseaseVeterinary (miscellaneous)Leaf scorchBiologyleaf scorchMicrobiology03 medical and health sciencesQuarantineOrnamental plantmedicinemedia_common.cataloged_instanceEuropean UnionEuropean unionEuropean Union pest risk plant health plant pest quarantine leaf scorch citrus variegated chlorosis Pierce’s disease olive quick decline syndromeHost (biology)citrus variegated chlorosisfungi15. Life on landbiology.organism_classificationmedicine.disease[SDV.BV.PEP]Life Sciences [q-bio]/Vegetal Biology/Phytopathology and phytopharmacyScientific Opinion030104 developmental biologyAnimal Health and Welfare[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologieAnimal Science and ZoologyParasitologyPEST analysisXylella fastidiosaplant health010606 plant biology & botanyFood Science
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Root architectural traits of rooted cuttings of two fig cultivars: Treatments with arbuscular mycorrhizal fungi formulation

2021

Abstract Many fruit tree species develop symbioses relationships with mycorrhizal fungi by which they improve their efficiency in water and nutrient uptake and, in turn, increase their vegetative growth and productivity, particularly under stressful environments. These benefits origin from the effects that mycorrhizal determined on the root architecture, morphology and physiology. Usually, few attentions has been devoted to the tree root structure and function, especially, in fig plants during their growth phase in the nursery. Recently, several root traits or phenes have been reported as fundamental for the root functions such as the root length ratio (plant’s potential for the exploitatio…

0106 biological sciences0301 basic medicinebiologyVegetative reproductionfungiFicusHorticulturebiology.organism_classification01 natural sciencesArbuscular mycorrhizal fungi Fig Image analysis Root architecture Root morphology Rooted cuttingSettore AGR/03 - Arboricoltura Generale E Coltivazioni Arboree03 medical and health sciencesHorticultureCutting030104 developmental biologyNutrientSymbiosisCultivarCaricaFruit tree010606 plant biology & botany
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